Marcos Castro Guarda

DPhil student in Physiology, Anatomy and Genetics - Cardiac metabolism @UniofOxford

[Medical Sciences @OxfordMedSci]

NEWS: @OxfordDPAG researchers identify a new metabolic axis which explains why the diabetic heart becomes fatty.

Pharmacologically targeting the enzymes regulating S-acylation can reverse the metabolic dysfunction and restore cardiac function in diabetes.
https://t.co/dtkwuCZXet

[Circulation Research @CircRes]

4/4 @KaitDennis19 et al FoxO1-zDHHC4-CD36 S-Acylation Axis Drives Metabolic Dysfunction in Diabetes https://t.co/e4SEpOR3jq @Heatherlab_ox @JussherLab @FullerLabGlas @dunjaaks @MarcosCG_95 @ujangpurnama_

[Circulation Research @CircRes]

@KaitDennis19 et al found #FoxO1-zDHHC4-#CD36 S-acylation axis drives metabolic dysfunction in #diabetes. Learn more at https://t.co/9dqXx31whJ
@heatherlab.bsky.social @heather_ox @JussherLab @FullerLabGlas @dunjaaks @MarcosCG_95 @ujangpurnama

[Heather Group @Heatherlab_ox]

🚨New from our group in @CircRes
We identify a FoxO1-zDHHC4-CD36 S-acylation axis driving metabolic + contractile dysfunction in the diabetic heart.
Blocking this pathway reprograms FA metabolism and improves heart function.
Read more:
🔗 https://t.co/eDblIq3pnt

[Marcos Castro Guarda @MarcosCG_95]

Last week, I successfully defended my DPhil thesis. I’m deeply grateful to my supervisor Prof Lisa Heather and colleagues. Thank you to my examiners Prof Sedej Simon and Prof Karl Morten for the wonderful discussion. @Heatherlab_ox @OxfordDPAG

[Society for Heart and Vascular Metabolism @Soc_HrtVasMetab]

🚨Mark your calendars🚨

‼️Registration for the 2025 SHVM- Shedding Light on Emerging Metabolic Targets in Cardiovascular Diseases will open on the 21st of January‼️

Check out our preliminary programme:
https://t.co/tQ1OGDJ5n8

Can’t wait to see you in Bordeaux 🫀👏

[Marcos Castro Guarda @MarcosCG_95]

Last week, I had an amazing time at @Soc_HrtVasMetab with my mentor and colleagues. I’m incredibly honoured and privileged to have received the William C. Stanley Early Investigator Award for my PhD work. Grateful for the opportunity to share our work! @Heatherlab_ox

[Marcos Castro Guarda @MarcosCG_95]

@rebeccahritchie Thank you very much!

[Heather Group @Heatherlab_ox]

Congratulations to our DPhil student @MarcosCG_95 on receiving the William C. Stanley Early Investigator Award at the #SHVM2024 @Soc_HrtVasMetab conference! His project focuses on the dual role of fumarate as an intracellular and extracellular hypoxia-induced signaling molecule

[ISHR European Section @ISHR_ES]

Congratulations to Lisa Heather for receiving the ISHR Research Achievement Award for her outstanding work on metabolic alterations in heart failure and diabetes! @ISHR_ECI @ISHR_LAT @IshrMci @ISHR_AUS @ISHR_NAS @ECI_ISHR @JMCCardiology @JMCCPlus @Heatherlab_ox @escardio

[Heather Group @Heatherlab_ox]

Amazing presentations by our DPhil students @MarcosCG_95 and @devereux_riona at the #SherringtonTalks @OxfordDPAG today! Well done!

[Journal of Molecular and Cellular Cardiology @JMCCardiology]

Open access! Work from @KN_Timm shows AICAR prevents loss of cardiac mass and ameliorates cardiac systolic function in a rat model of doxorubicin-induced heart failure: https://t.co/InLpqWVS9A

@k8weeks @vagnozzirj @monikagladka @ELS_Cardiology

[Marcos Castro Guarda @MarcosCG_95]

Thank you for the opportunity to present my DPhil project at #MitOX2024 annual meeting last week. Had a great day of learning.
@Heatherlab_ox @OxfordDPAG

[British Society for Cardiovascular Research @BSCResearch]

And last but not least for session 5; Marcos Castro-Guarda tells us how fumarate reprogrammes metabolic preferences and antioxidant profile within the cardiomyocyte

[Heather Group @Heatherlab_ox]

We had a wonderful two days at the 50th anniversary meeting of the @BSCResearch! So many wonderful talks among which were those by Prof. Lisa Heather and @MarcosCG_95!

[Heather Group @Heatherlab_ox]

Congratulations @MarcosCG_95 on winning the top poster prize 🏆 at MitOX 2023 hosted at the University of Oxford last week! @DPAGPostdoc #research #mitochondria

[Atenea Uribe Ojeda @AteneaUribe]

So happy with my #cytosis game from the @Co_Biologists at the #DynamicCellV

[Heather Group @Heatherlab_ox]

🚨New review! 🚨
Excited to share this new review written by @KaitDennis19 and Lisa Heather @Heatherlab_ox just published in Frontiers in Physiology @FrontPhysiol.
Check it out on the link below.

https://t.co/IUTRszgGz5

#palmitoylation #lipidation #metabolism #WomenInSTEM

[Society for Heart and Vascular Metabolism @Soc_HrtVasMetab]

Happy international women and girls in science day to all the women serving on the SHVM executive board and all of the talented women in the SHVM family #WomenAndGirlsInScience #WomenInSTEM #WomenInScience #SHVM

[Heather Group @Heatherlab_ox]

Congratulations, @MarcosCG_95 on winning first prize at IMPRES 2022 (International symposium of Pharmacy Research)!! @DPAGPostdoc @OxfordGradStudy #cardiovascular #metabolism