NEWS: @OxfordDPAG researchers identify a new metabolic axis which explains why the diabetic heart becomes fatty.
Pharmacologically targeting the enzymes regulating S-acylation can reverse the metabolic dysfunction and restore cardiac function in diabetes.
https://t.co/dtkwuCZXet
🚨New from our group in @CircRes
We identify a FoxO1-zDHHC4-CD36 S-acylation axis driving metabolic + contractile dysfunction in the diabetic heart.
Blocking this pathway reprograms FA metabolism and improves heart function.
Read more:
🔗 https://t.co/eDblIq3pnt
Last week, I successfully defended my DPhil thesis. I’m deeply grateful to my supervisor Prof Lisa Heather and colleagues. Thank you to my examiners Prof Sedej Simon and Prof Karl Morten for the wonderful discussion. @Heatherlab_ox@OxfordDPAG
🚨Mark your calendars🚨
‼️Registration for the 2025 SHVM- Shedding Light on Emerging Metabolic Targets in Cardiovascular Diseases will open on the 21st of January‼️
Check out our preliminary programme:
https://t.co/tQ1OGDJ5n8
Can’t wait to see you in Bordeaux 🫀👏
Last week, I had an amazing time at @Soc_HrtVasMetab with my mentor and colleagues. I’m incredibly honoured and privileged to have received the William C. Stanley Early Investigator Award for my PhD work. Grateful for the opportunity to share our work! @Heatherlab_ox
Congratulations to our DPhil student @MarcosCG_95 on receiving the William C. Stanley Early Investigator Award at the #SHVM2024@Soc_HrtVasMetab conference! His project focuses on the dual role of fumarate as an intracellular and extracellular hypoxia-induced signaling molecule
Open access! Work from @KN_Timm shows AICAR prevents loss of cardiac mass and ameliorates cardiac systolic function in a rat model of doxorubicin-induced heart failure: https://t.co/InLpqWVS9A
@k8weeks@vagnozzirj@monikagladka @ELS_Cardiology
Thank you for the opportunity to present my DPhil project at #MitOX2024 annual meeting last week. Had a great day of learning.
@Heatherlab_ox@OxfordDPAG
And last but not least for session 5; Marcos Castro-Guarda tells us how fumarate reprogrammes metabolic preferences and antioxidant profile within the cardiomyocyte
We had a wonderful two days at the 50th anniversary meeting of the @BSCResearch! So many wonderful talks among which were those by Prof. Lisa Heather and @MarcosCG_95!