Marcus Bage

Bioinformatician @PDBEurope. Standardising and enriching protein modification data in structure models.

[Protein Data Bank @PDBeurope]

The PCM and PTM remediation has started and we are so hyped!
⬇️ Read more ⬇️
https://t.co/IGjQrTjaas

[Dr Javier Sánchez Utgés @javierutges.bsky.social @JavierUtges]

Really glad to see our work published in @Nature @CommsBio: https://t.co/46XqPNW5yi.
This analysis of 39 fragment screening experiments sets the scene for our future work on function prediction for ligand sites across the @PDBeurope. @gjbarton @bartongrp @stuartmac44 @CallumMIves

[IBDC (Indian Biological Data Centre) @ibdctweets]

Maxim Tsenkov: curating the biological functions of proteins using the AlphaFold Protein Structure Database

[Protein Data Bank @PDBeurope]

Are you a front-end developer interested in biological data? We have a post available for development of user-facing web pages for displaying molecular structures & annotations.
📅Deadline: 19 March 2024.

For more information and to apply:
🔗https://t.co/DeeE6eiZzp

[EMBL-EBI Training @EBItraining]

In our newest practical guide, developed with @GoogleDeepMind and @emblebi, delve into the fundamentals of #AlphaFold, explore its strengths and limitations, and gain practical skills through hands-on exercises.

Start the free, self-paced tutorial today: https://t.co/t8UIlUtQzz

[Protein Data Bank @PDBeurope]

Excited to join @aibc2024! Visit our poster today, chat with @deeptigupta19 and @PDBeurope team. Grab some awesome #PDBe stickers and #PDBart calendars to take home. Don't miss out! See you there! 🧬🔬@gobalbiodata #AIBC #BiocurationConference @unescorb #Datascience

[Protein Data Bank @PDBeurope]

Celebrating Sunday's #WorldWildlifeDay, we’re highlighting a key player in stress response: the glucocorticoid hormone ➡️ managing stress & inspiring art... #PDBart

More:
🔗 article:
https://t.co/0Re6QAzu8r
🔗 protein structure:
https://t.co/oHcZdsCgUv

[Marcus Bage @Marcus_Bage]

A great start to #AIBC2024, with a workshop exploring #glycosylation, #biocuration and the dissemination of biological data, held by @gly_gen, @CfdeNih and @aibc2024. I'm looking forward to all the discussions that come out of the next few days.

[Deepti Gupta @deeptigupta19]

Thrilled to join #AIBC @aibc2024 with @Marcus_Bage and @mitsenkov representing @PDBe and #AlphaFold DB, diving into the world of #biocuration. Anticipating inspiring opportunities at this global biocuration meet @PDBe @wwpdb #AlphaFold @globalbiodata @unescorcb #DataScience 🌍✨

[Maxim Tsenkov @mitsenkov]

Thrilled to be at #AIBC2024, for a fantastic gathering of @biocurator experts. Here with @PDBeurope to showcase use cases with #AlphaFold DB and highlight its utility in the #biocuration field. Eager to learn from you, so let’s connect and discuss! @unescorcb @globalbiodata

[Protein Data Bank @PDBeurope]

In October 2023, wwPDB will roll out updated CCD data files with additional annotation and standardized atom naming of peptide residues. Find out more about these changes and how they will affect you: https://t.co/cm8TgPmmyO

[Protein Data Bank @PDBeurope]

When hexokinase phosphorylates six-carbon sugars, it toggles between conformational states. The #PDBeKB’s new #Alphafold superposition tool suggests the predicted model adopts the sugar-bound conformation. See how the new tool can help your research!
🔗https://t.co/h4N3Y6ttnh

[Callum Ives @CallumMIves]

Our work from @UZDundee group on PorB is now available in @BBAjournals! This interdisciplinary collaboration utilises X-ray crystallography, electrophysiology & MD simulations to study porin-based drug-resistance in Gram-negative bacteria @UoDLifeSciences https://t.co/BQblwlalQj

[GRE Dundee @GREDundee]

Latest collaborative research from @AndreiPisliakov & @Vichaico has identified novel interaction sites on the mRNA Capping Enzyme that are essential for its activity. Work published in @NAR_Open with @Marcus_Bage first author 👏
https://t.co/1WIys7eqjo

[UoD Life Sciences @UoDLifeSciences]

Latest collaborative research from @AndreiPisliakov & @Vichaico has identified novel interaction sites on the mRNA Capping Enzyme that are essential for its activity. Work published in @NAR_Open with @Marcus_Bage first author 👏
https://t.co/4WOw219lUj

[Open Research, University of Dundee @UoDOpenResearch]

🔓 #OpenAccess

A novel RNA Pol II CTD interaction site on the mRNA Capping Enzyme is essential for its allosteric activation

➡️https://t.co/rUtvKP0nkX

@UoDSciEng @UoDLifeSciences @GREDundee @Marcus_Bage Dr Almohammed @Vichaico @AndreiPisliakov
#RNA #Polymerase II

[Andrei Pisliakov @AndreiPisliakov]

Our new paper on regulation of RNA Capping Enzyme by CTD of #RNA #Polymerase II is out in Nucleic Acids Research! Excellent work by PhD student @Marcus_Bage and great collaboration with Vicky Cowling’s lab @Vichaico.

biomolecular simulations; allostery

https://t.co/7YeqrQpFKr

[Marcus Bage @Marcus_Bage]

@MagdaSovakova Thanks Magdalena! I hope you're enjoying your next rotation! 😀

[Marcus Bage @Marcus_Bage]

Delighted to see my first first author paper online today! We use simulations to find RNA PolII CTD binding sites on the mRNA Capping Enzyme and uncover their vital role in allosteric activation. Of interest to anyone using MD to study PPIs and allostery! https://t.co/At9tijIsXq

[Marcus Bage @Marcus_Bage]

A huge thank you to everyone involved in the work @AndreiPisliakov @Vichaico and Rajaei.