Marius Regin

MD/PhD

[Marius Regin @MariusRegin]

Our revised version on the consequences of aneuploidy in human embryos is now online @eLife

https://t.co/eYFPumPly3

[Zuzana Storchova @ZStorchova]

Gene dosage compensation of somatic aneuploidy is frequent in cancer. Using machine learning, we find factors that predict dosage compensation, and show its adaptive features, its role in drug sensitivity and gene dependency.
https://t.co/lGVzPE68WH

[Anchel de Jaime-Soguero @Anchel_91]

Happy to share my first prelight. If you are intested in how human embryos deal with changes in the environment, please have a look!

[VUB @VUBrussel]

Stem cell treatment offers new therapeutic perspectives, but major health risks still pose some challenges. @VUBrussel research team led by prof. @ClaudiaSpits developed new safety mechanisms to limit these risks: https://t.co/bEvkv4IFhA

[Martin Pera @martinperaJAX]

Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos https://t.co/ZFuhIBgyP2

[Stefano Santaguida @SteSantaguida]

Excited to see our latest paper on micronuclear collapse featured on the cover of @ScienceMagazine 🧬🔬

[Sergio Perez Acebron @Acebron]

How does genomic mosaicism arise during development? We identified that embryo patterning signals not only readour genetic blueprints to build organisms, but they also play a critical role in their maintenance. A quick dive into our new paper https://t.co/KCFxEFaERI 1/10

[Martin Pera @martinperaJAX]

Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating re… https://t.co/FlqvqB0MWg

[Martin Pera @martinperaJAX]

De novo cancer mutations frequently associate with recurrent chromosomal abnormalities during long-term human pluripotent stem cell culture https://t.co/HwZh2pSEXF

[Magdalena Zernicka-Goetz @ZernickaGoetz]

What is the origin of our body? Our paper @CellCellPress shows that when a human embryo is one day old and comprises just two cells, only one cell will create most of the fetus in addition to placenta, while the other cell will create placenta.
https://t.co/88l48YezzA

[VUB @VUBrussel]

@VUBrussel and @UZBrussel researcher Claudia Spits discovered the genetic cause of low birth weight after in vitro fertilization. A complex link between increasing number of obtained eggs through hormone therapy and higher risk in mutagenic mitochondria https://t.co/128bzNvkmB

[Nicolas Rivron @NRivron]

Our laboratory for blastoid development and implantation is seeking a postdoctoral fellow to work with us on human embryogenesis. Our core-funded laboratory is located at the IMBA Institute of the Austrian Academy of Sciences in amazing Vienna. Please reTweet and get in touch!

[Nature Methods @naturemethods]

It's that time of year!! 🎉We are so excited to announce our 2023 pick for Nature Methods' Method of the Year: methods for modeling development. Read the Editorial to find out why we chose this as our pick. #moty2023

https://t.co/RNLeOZLE52

[Dr. Karen Sermon @SermonKaren]

If you are still wondering how badly chromosomal abnormalities in human pluripotent stem cells can mess up your differentiation experiments, check out the latest work from our team and especially @KrivecNusa and @ClaudiaSpits : https://t.co/2RgUqjvSMW

[Marius Regin @MariusRegin]

Our reviewed preprint is now online
@eLife ! We investigated the cellular consequences of aneuploidy in human embryos. Our study may contribute to understanding how aneuploid cells are selectively eliminated in mosaic embryos. Enjoy 😎.

https://t.co/Lk9WkpvKqp

[Jason Sheltzer @JSheltzer]

Check out our new study in @ScienceMagazine, where we take on a 100-year-old debate: what’s the role of aneuploidy in cancer?

We discovered that genetically removing extra chromosomes blocks cancer growth - a phenomenon we call “aneuploidy addiction”. https://t.co/K5ny7Ureph

[Development @Dev_journal]

What do cows, mice, rats and humans have in common? Let's ask the Hippo

A Research Highlight showcasing new work from @ClaudiaGerri @NiakanLab and colleagues @TheCrick

https://t.co/VjYSCJUFKY

[Human Molecular Genetics @hmg_journal]

Mitochondrial DNA variants segregate during human preimplantation development into genetically different cell lineages that are maintained postnatally https://t.co/pF5HgvxpIb

[Claudia Spits @ClaudiaSpits]

We are looking for a lab manager to join our team!
We have a great lab with new and beautiful facilities, were do do research on stem cell biology and early human development... (check us out https://t.co/y4zI3ojXJM)

[bxv_dev @bxv_dev]

Lineage segregation in human pre-implantation embryos is specified by YAP1 and TEAD1 https://t.co/EeCC2uZWZB