Martin D Muggli, PhD

Bioinformatician, computational linguist, programming language/compiler/FPGA enthusiast, teacher. he/him

[Martin D Muggli, PhD @MartinDMuggli]

CS inspired life hack: I think a second dishwasher would be superior to cabinets. One could swap the 'write' and 'read' labels ala double buffering. It would reduce the number of times a dish needs to be touched throughout its use cycle.

[Martin D Muggli, PhD @MartinDMuggli]

@NVIDIAGeForce @GearsofWar #RTXPowersPlay

[Dave W Plummer @davepl1968]

I suppose there's a whole class of programmers for whom a compiler is akin to magic, but knowing what's getting emitted and how it works is fundamental to your success over the long haul.

Write some assembly. Read the Dragon book on an airplane. AI will still be here when you get back.

In five years, anyone capable of structured thought will be able to become a prompt engineer, but only 1% of software developers will actually be able to debug the stuff that comes out the other end.

Be the 1%

[Martin D Muggli, PhD @MartinDMuggli]

New term for focus just dropped: "rotating brain waves"

[Neuroscience News @NeuroscienceNew]

Rotating Brain Waves Help the Mind Refocus After Distraction

New research reveals that the brain regains focus after distraction through rotating waves of neural activity.

These circular waves sweep across the prefrontal cortex, realigning neurons and restoring attention.

When the rotations fully complete, performance remains sharp; when they don’t, mistakes increase.

The discovery shows how the brain uses efficient analog computation to keep thought processes on track.

[Martin D Muggli, PhD @MartinDMuggli]

https://t.co/psJzWCF6Ib

[Martin D Muggli, PhD @MartinDMuggli]

@DrDanielJordan Nice talk!

[Martin D Muggli, PhD @MartinDMuggli]

Come hear about #Bionano's new #heme/low allele fraction SV focused guided assembly pipeline this afternoon at poster 3444 at #ASHG2023

[Martin D Muggli, PhD @MartinDMuggli]

I like the vision he has. I knew all the facts he states, but didn't see this angle till he said it. https://t.co/eI7yMsYbQ0

[Martin D Muggli, PhD @MartinDMuggli]

@ThisDoesNotComp Could I buy the leftovers from this project from you?

[Pema99 @pemathedev]

So I was experimenting with a kind of variable rate shading in my toy path tracer today, and doing some questionably valid stuff with unsynchronized memory accesses. Suddenly a sierpinski triangle appears in random garbled mess I've created. What even.... O.O

[Martin D Muggli, PhD @MartinDMuggli]

@shurtis123 @yazzy1967 @jonstewart At least not knowingly. Jonathan Swan clearly wasn't what Trump was expecting.

[Martin D Muggli, PhD @MartinDMuggli]

@lemire I'm still disappointed x32 ABI never caught on. Cache savings of 32 bit pointers with access to all the registers of x86-64.

[Martin D Muggli, PhD @MartinDMuggli]

@JossFong This is a huge pet peeve of mine. It's basically an advertisement and should be labeled as such.

[Martin D Muggli, PhD @MartinDMuggli]

@mooreds Somehow reminds me of the quote "write drunk, edit sober"

[Martin D Muggli, PhD @MartinDMuggli]

@CQnib @nomad421 I'm guessing all the carbon we're producing will be with us for ~100.000y too and will have far more reach and impact.

[Martin D Muggli, PhD @MartinDMuggli]

@JossFong Adding pseudoephedrine can help congestion a lot too, but make sure your antihistamine doesn't already have it (e.g., Claritin-D). You need to ask the pharmacist for it.

[Yann LeCun @ylecun]

To clarify:
LLMs that auto-regressively & reactively predict the next word are an off-ramp. They can neither plan nor reason.

But SSL-pretrained transformers are clearly a component of the solution, within a system that can reason, plan, & learn models of the underlying reality.

[Michael Locklear @MichaelLocklear]

Salt Lake City public lands officials hiked up the snowy Twin Peaks trail today to remove a mysterious device (solar panel, antenna & locked battery box). They're finding more in the foothills, with no explanation as to who's putting them there -- or why. Story on @KSL5TV at 6

[Martin D Muggli, PhD @MartinDMuggli]

@kephasp @IanArawjo I don't think pointers are hard if one's first language is assembly.

[Barış Ekim @ekimbarisc]

Just in time for the New Year: In our new preprint with @krsahlin, @pashadag, @lab_berger, and @RayanChikhi we describe mapquik, a blazing-fast HiFi-read mapper, using k-min-mer seeds (consisting of k consecutively-sampled minimizers). https://t.co/bxJsWhdyKl

[Martin D Muggli, PhD @MartinDMuggli]

@brent_p Sussman gave a talk about why they stopped teaching SICP at MIT and it mentioned this. See https://t.co/Qd5RXytIEH