Marvel UC Trial

Phase 2b Randomised placebo-controlled trial into oral Mitochondrial antioxidants (MitoQ) to treat active Ulcerative Colitis in UK. We are open for recruitment!

[Marvel UC Trial @MarvelTrial]

We recruited our 1st patient from NHS Clyde! Wonderful to extend our reach to under served research communities! Thank you Graham Naismith, Jonathan Macdonald and GI team @NHSGGC @GlasgowCRF #ibd #clinicaltrials #ulcerativecolitis #paisley

[Marvel UC Trial @MarvelTrial]

Delighted to welcome Cambridge as a new MARVEL recruitment site! Our study is now active across UK looking at mitochondrial antioxidants in Ulcerative Colitis! https://t.co/gBP7sIoRTW #UC #Colitis #trial #mitochondria #Cambridge

[Marvel UC Trial @MarvelTrial]

Thanks @NHSGGC for recruiting our 70th!

[Marvel UC Trial @MarvelTrial]

June was a good month for https://t.co/gBP7sIppJu London, Manchester, Edinburgh and Glasgow working hard & we've broken through n=70 participants 🎊. Hugely grateful for this big team effort.

Testing the novel idea of adding oral mitochondrial antioxidants for UC! #ibd #Trials

[Glasgow Edinburgh IBD Science @GlasgowEdin_IBD]

We are delighted to be training many Associate Principal Investigators via the @NIHRresearch.

8 Associate PIs so far! Via our MARVEL UC study https://t.co/WCURnijA0j

Vital to sustain clinical research and the next generation of researchers.

https://t.co/AGRx9Ioxmh

[Glasgow Edinburgh IBD Science @GlasgowEdin_IBD]

Delighted to recruit our 1st MARVEL patient in St George's London, we're making good progress! https://t.co/WCURnij2aL clinical trial in #mitochondrial antioxidants in Ulcerative Colitis. #trials #uc #IBD

[Gwo Tzer @Gwotzerho]

It was lovely to share this special day with so many people. Thank you everyone for coming. Many wonderful people who helped me to where I am today. @UofGSii

This one is for my late parents who would have dearly loved to be here today.

[Glasgow Edinburgh IBD Science @GlasgowEdin_IBD]

Our group have studied 💩 stool #calprotectin vs. #QFIT (that can detect blood used as screening for bowel cancer) to monitor #IBD .

We are looking for the 'patient voice' in our study, so very grateful for your time, share and RT!

[Glasgow Edinburgh IBD Science @GlasgowEdin_IBD]

Very proud of our CCUK Research Champion @emmapryde7 in this month's Connect. You've been amazing! #IBD #PPIE

https://t.co/quDWiCvFgs

A picture paints a thousand words!

[Gwo Tzer @Gwotzerho]

Congratulations to Dr Robert Whelan! Successful PhD viva defence on the role of oral #microbiome in IBD. Thanks George Hold & Rodger Duffin for examining & MRC Precision Medicine for supporting this excellent thesis! #crohns #ibd @EdinUni_CIR
2nd Ho-lab #PhD in 2025 @UKRI_News

[Glasgow Edinburgh IBD Science @GlasgowEdin_IBD]

We've recruited our 60th patient for https://t.co/WCURnij2aL! Congratulations to #Glasgow team for reaching this milestone. We are testing mitochondrial antioxidants as addition to current treatment for #ulcerativecolitis @NHSResearchScot @NHSGGC #ibdtrials @CrohnsColitisR

[Glasgow Edinburgh IBD Science @GlasgowEdin_IBD]

What happens if patients take the lead in an IBD project?

Result: A wholly patient-led paper on ''What it means to live with IBD'.

🧵on how our patient-public involvement (PPI) #IBD came about....

#Crohns #colitis #PPIE #patientinvolvement

https://t.co/ewo9otZQC3

[Glasgow Edinburgh IBD Science @GlasgowEdin_IBD]

East-West connection made with China Crohn's Colitis Foundation #ibd #crohns #globalibd #ecco2025 #china

[Marvel UC Trial @MarvelTrial]

A good week for our study. We recruited 4 (!) into MARVEL including our 1st from #Manchester! Big thanks to Prof Limdi and his team. Mitochondria antioxidants in UC https://t.co/gBP7sIoRTW #ulcerativecolitis #mitochondria #ibd @Edin_IBDScience

[Marvel UC Trial @MarvelTrial]

Congratulations #Glasgow IBD @j0nnymac1 another 2 patients with flaring Ulcerative Colitis #uc recruited into MARVEL mitochondrial antioxidants treatment. Key work to find new ways to treat Colitis! #ibd #mitochondria #trials @Edin_IBDScience

[Glasgow Edinburgh IBD Science @GlasgowEdin_IBD]

New ways to treat IBD? - #metabolism and the #mitochondria. Our review 👇. #crohns #uc #ibd #immunometabolism
https://t.co/RPTZTzRtam

[Marvel UC Trial @MarvelTrial]

Our fab research team after recruiting of 51st MARVEL patient! Trial looking at mitochondrial antioxidants in UC. #mitochondria #ulcerativecolitis #clinicaltrial @NHSResearchScot @CSO_Scotland @CrohnsColitisR @Edin_IBDScience

[Marvel UC Trial @MarvelTrial]

We recruited our 50th patient today. Small investigator-led clinical trials in IBD are immensely challenging. Thank you to all our patients, partners and team across UK! #mitochondria #clinicaltrial #ibd @Edin_IBDScience @NHSResearchScot @BritSocGastro @CrohnsColitisR

[Glasgow Edinburgh IBD Science @GlasgowEdin_IBD]

Amazing progress by Paediatric team! MiniMUSIC https://t.co/flMCP4dZBq >50% (34/60) target of newly diagnosed Crohn's disease achieved way ahead of schedule! V positive response from young patients + families across Scotland #crohns @CrohnsColitisR @echcharity #pibd @UofGlasgow

[Glasgow Edinburgh IBD Science @GlasgowEdin_IBD]

A fine morning with Emma and Tricia, our CCUK Patient Research Champions, sharing their lived experiences as part of our Patient-led engagement work! @CrohnsColitisR #crohns #Colitis #ibd #ulcerativecolitis @CrohnsColitisUK