Max Mossner

Cancer genomics guru + chilli pepper vampire

[Trevor Graham @trevoragraham]

#postdoc positions in our interdisciplinary #cancer #evolution @CEC_ICR lab @ICR_London. Applicants from maths/physics/computer science/quantitative genetics backgrounds are particularly welcomed. Do drop me a line to discuss. https://t.co/nVpqewxno4

[Freddie Whiting @WhitingFreddie]

I am excited to advertise an opportunity for a scientific officer position to work with me and
@trevoragraham to experimentally test predictions about therapy resistance evolution in our group at the
@ICR_London, @CEC_ICR

Application here:
https://t.co/fnfIAFD7Bt

[Max Mossner @MaxMossner]

@ICR_London @CEC_ICR @gcresswell @trevoragraham Big thanks to @RachelParkerRes for video recording expertise!

[The ICR @ICR_London]

Welcome to the ICR’s GEDy Lab Twitter takeover! In celebration of this year’s Evolution Day, we invite you to a tour of our lab in @CEC_ICR highlighting our work on understanding and tackling cancer evolution. @maxmossner @gcresswell @trevoragraham

[Trevor Graham @trevoragraham]

How do the #genome, #epigenome and #transcriptome co-evolve in colorectal #cancer? In the second of two papers in @nature, we find gene expr is not strongly heritable & evaluate "driverness" of muts directly in patient tumours https://t.co/11goJRjWgT @AndreaSottoriva #EPICC2 1/7

[Andrea Sottoriva @AndreaSottoriva]

How do the #genome, #epigenome & #transcriptome co-evolve in colorectal #cancer? In the 1st of 2 studies in @Nature we measure the contribution of #chromatin accessibility in #cancer #evolution. #genetics and #epigenetics interplay! #EPICC1 @trevoragraham
https://t.co/SqjatBp4Yn

[Max Mossner @MaxMossner]

The future of UK medical research is at risk, including pioneering projects that I work on for @CRUK_Policy.

@HackneyAbbott as my MP, please sign this letter to show your support and help us continue to make progress for patients https://t.co/0JUJWtclEw

#ResearchAtRisk

[Trevor Graham @trevoragraham]

More distraction: new #preprint we posted a little while ago https://t.co/5niFLLkMK5 looks at somatic copy number #evolution in #colorectal #cancer. Suggests a #CNA bottleneck adenoma->cancer, & thereafter CNAs experience #stabilising #selection, remarkably even in mets & chemo.