Massimo Saini

Cancer researcher at ETH Zurich

[Massimo Saini @Max_sa999]

Out now!

[Cell @CellCellPress]

Now online! StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models https://t.co/C1w6T7CxRb

[Cell @CellCellPress]

Now online! StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models https://t.co/C1w6T7CxRb

[Massimo Saini @Max_sa999]

@AdrianoAguzzi Perhaps they dilute antiseptics in water, which is fine since they are "energized" shortly beforehand

[Massimo Saini @Max_sa999]

@AdrianoAguzzi @SelinaWray Then it should be nobody. Otherwise it's not going to change.

[Massimo Saini @Max_sa999]

@AdrianoAguzzi PMT voltages seem to be different in the 4sg with respect to individual sgs

[EACR @EACRnews]

Nicola Aceto is this year’s @pezcoller-EACR Translational Cancer Researcher Award winner! #EACR2023

[D-BIOL @ ETH Zurich @ETH_DBIOL]

Resistance to EMT promotes breast cancer spread; unexpected results from a collaboration between @ETH_en, the Helmholtz Centre Munich and DKFZ. The analysis of patient-derived biopsies sheds new light on metastasis-forming events in breast cancer. More: https://t.co/xEb4nFSnq9

[Mammary Cell News @MammaryCell]

Cheers to @hi_stem_lab members on their recent publication! 🥂

They show that susceptibility to irreversible EMT restrains clonal propagation, whereas resistance to #mesenchymal reprogramming sustains disease spread in #BreastCancer models.

👉 https://t.co/bG1UkIITzz

[Ying Cao @NeuralGrndState]

>40000 EMT papers so far, many of which published in journals requiring the highest level of rigor and the best physiological relevance.

But no one knows (roughly) what a mesenchymal state is, and the unknown stuff controls everything of cancer cells.

https://t.co/At0MHdKFhe

[Massimo Saini @Max_sa999]

What's the impact of EMT on breast cancer cells, if we look at real-life metastatic patients? Quite not what we expected. Check it out here 👇

[Cell Reports @CellReports]

Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer https://t.co/5c1lzYpjpD

[Cell Reports @CellReports]

Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer https://t.co/5c1lzYpjpD

[Enrique Grande @drenriquegrande]

⚡️Cancer immunotherapy: T cells & neutrophils working together to attack cancers

#immunotherapy

https://t.co/hP3fFLRWm1

[Fyodor Urnov @UrnovFyodor]

I wonder if ChatGPT could be used to ask this question during peer review:
"Has one key finding of this work been published before?"
In this case the answer would be "yes" (in 2007).
Clearly we need AI since "human I" appears to have underperformed here.
#smh

[Luca Cassetta @CassettaLuca]

On Monday I lost my mentor, my friend, my business partner, my scientific father, Jeffrey Pollard.
Jeff inspired every second of my life with his passion, scientific integrity and emotional intelligence.
He left an incredible legacy which made him immortal. I love you Jeff ❤️

[Massimo Saini @Max_sa999]

@paolomossetti Attendiamo le fonti bibliografiche. Solitamente invano, quando si tratta di Crisanti.

[Massimo Saini @Max_sa999]

@massimosandal That for sure. I mean: are you curious about tumor suppressor genes and COVID for specific reasons?

[Massimo Saini @Max_sa999]

@massimosandal What do you mean, specifically?

[Alberto Angela @albertoangela]

Buon viaggio papà.

[Massimo Saini @Max_sa999]

@giorgiogilestro Sì non c'è un nesso solido. Il problema é che non é così clear-cut la differenza tra un adenovirus respiratorio e uno gastrointestinale, e descriverli come fossero sempre e solo dei virus da raffreddore non aiuta.

[Massimo Saini @Max_sa999]

@giorgiogilestro Non è del tutto esatto, questo. Gli adenovirus gastroenterici sotto accusa (Ad40 e Ad41) hanno un tropismo gastroenterico, e quando causano sintomi si tratta di sintomi tipo diarrea e altri disturbi del tratto digestivo, non il naso che cola.