Keen interest in current happenings in pharma world. A clinical researcher by profession. All views expressed are my own. Links and RT are not endorsements
25-40% of clinical trial costs come from an excessive quality-check process that the FDA itself has recommended against for over a decade.
Great piece from a former FDA official on why the whole system is stuck in a "too big to fail" loop.
https://t.co/yX4gNVy04k
Pushpa 2 is not actually a movie. A movie is supposed to have a story, screenplay, a plot, an arc and in most cases, a closure.
Pushpa 2 has none of that.
It is a patchwork of incoherent and illogical videos, written by a group of people who have Allu Arjun tattoos on their chests and worship and pour milk over his photo every day.
Which means the entire movie is basically Allu Arjun roaming about doing Hero Stuff, speaking hero dialogues, to people whose only job is to line up in a single file and have the privilege to get hit, bit, stabbed and killed by him. Yes, he does all of that.
The movie starts off pretty badly, with our hero going to Japan for no reason, beats the shit of some 300 Japanese gangsters while speaking Punch dialogues in Japanese, leaving you completely dazed as to what the hell is happening.
And then it goes downhill faster than a fully loaded freight train with failed brakes
Because what follows is a 3 hour and 20-minute barrage of garish, mind-numbing scenes, which have zero connection between each other.
All you get is a series mindless fight sequences interspersed with random dream sequences, pointless songs and a raunchy item number which serves no purpose other than titillation.
There is no edge of the seat action. There is no thrill. There is no adventure. There is absolutely nothing.
In fact, midway thru the movie, even the director realizes this.
So, in a brave attempt to save the movie, he conjures a random sentimental story arc out of absolutely nowhere, completely dissociated with the main story arc, all for the express purpose of giving Allu Arjun the chance to kill more people on screen in very badly choreographed ways.
However, by the time this scene comes on screen, you are already looking at your watch or phone and are trying to determine how much longer this torture is going to last. And somewhere deep in your heart, you are also wondering what sins you committed in your past life that you are stuck in this movie hall, watching this movie.
As for the actors, Fahadh Fasil overacts and overhams, Rashmika does the bare minimum that is needed for her paycheck, the minister guy is ok and it looks like Jagapathi Babu accidentally walked into the set of the movie and got a role.
As for Allu Arjun, well, what he does is irrelevant, because he has stopped acting a long time ago.
As I said before, Pushpa 2 cannot be called a movie. At best it can be called a shoddily assembled collection of moving images consisting mostly of badly made reels and shorts with no common thread.
Pushpa 2 is just 3 hours & 20 mins of Allu Arjun killing people and mouthing badly written punch lines.
I don't know at the end of the movie you will get happiness or satisfaction, but you surely will get a headache or migraine.
But then this movie will also mint 1000 crores and join the list of Jawaan, Pathaan, Kalki and other such masterpieces, which reinforces the belief that you no longer need story or quality, to make huge money at the box office.
Any nonsense will do.
A very sad side effect of this, is that our future generations, will never ever, get to watch a good movie.
Eli Lilly’s obesity drug Zepbound cut the risk of complications and improved symptoms in patients with a common type of heart failure, the second GLP-1 drug with positive results in… https://t.co/HMFIFrieQa
“As I look back on my life, I realize that every time I thought I was being rejected from something good, I was actually being re-directed to something better.”
Rafa Nadal after playing his final match in Madrid:
“This is one or those times where when it arrives, it's very difficult… but life and my body have been sending signals to me for a long time. My dream was to finish here on court. I have been fortunate in my life to turn my passion into my job. I am privileged.” 🥹
KOBE BRYANT’S 10 RULES
1. Get better every single day
2. Prove them wrong
3. Work on your weaknesses
4. Execute what you practiced
5. Learn from greatness
6. Learn from wins and losses
7. Practice mindfulness
8. Be ambitious
9. Believe in your team
10. Learn storytelling
Beautiful words to remind us of the year gone by and the year ahead. Thank you @AnupamPKher for starting my 2024 with such thoughtfulness! Happy New Year to you and @KirronKherBJP ji.
Paul Assaiante is described as the “winningest” coach in college sports.
He embraces a philosophy called “run to the roar,” which explains that your biggest success often lies behind your greatest fears.
Here are some insights from the episode:
1. The competition isn’t where you win. You win on the practice field. You win by putting in the reps on a random Tuesday when no one is watching, not gearing up for a match with Harvard on Saturday. Success is found in the preparation.
2. Practice your weaknesses, but compete to your strengths. What does this mean? If you can’t hit a backhand, you should be practicing a backhand rigorously. But on game day, play to a front-hand. Inevitably, when a back hand is required, you’ll be ready. The more you can reduce your weaknesses, the more you’ll win.
3. Consistent, daily effort is key to success. You don’t become a superb tennis player by pulling all-nighters before a tournament. Similarly, you won’t get the best grade possible by waiting until the last minute to study for an exam. When you put in a little every day, you put yourself in the best possible position to succeed when the “test” comes.
4. Lack of consistency may not be a lack of discipline, but a lack of excitement.
5. Nobody makes a bad decision intentionally. A bad decision is often a result of not taking a pause between your thoughts and your actions.
6. In-game adjustments are the key to life. You can prepare and visualize and get ready for whatever might happen during the “game,” but inevitably, something will happen that you didn’t expect. The most successful people recognize that and react accordingly.