The #OHS pyramid is cited as a reason for denying health workers optimal #PPE. We argue that for health workers, if the hazard IS the infectious patient, the OHS pyramid is not fit for purpose. We propose a new approach. #masks#N95#Ebola https://t.co/nzY9K33ps0
More suspected #H5N1 in Australia today. Our PhD student Pan Zhang was studying the risk of H5N1 to Australia before it reached us. Here is our interactive map predicting where #poultry outbreaks are likely to occur using a Maxent model. Click the arrow at top RHS to see data layers. Hover over areas to see names.
https://t.co/tEAueDqy3V
From the analysis of the cumulative quality-adjusted life-year (QALY) loss attributable to fatal and nonfatal COVID-19 outcomes in the United States,
"We estimate the cumulative QALY loss [due to COVID-19] as 9,242,000 life-years.
Following deaths, long COVID was the second most significant contributor to QALY loss, with an estimated annual QALY loss of approximately 865,000.
This burden is comparable to the total annual disability-adjusted life-years (DALYs) associated with liver cancer: 581,000 DALYs..
[In conclusion,] The quality-of-life burden of nonfatal COVID-19 outcomes, particularly long COVID, is on the same scale as that of major chronic and infectious diseases."
Our quality of life is surely declining.
'Estimating the Quality-Adjusted Life-Year Loss due to Fatal and Nonfatal COVID-19 Outcomes across US States and Counties, July 2020 to December 2022'
https://t.co/P4yX6GRyBH
Important research that supports the work of Chris Warren & others which suggested #smallpox may have used deliberately against the Port Jackson Aboriginal people who fiercely resisted the First Fleet. At the time, the Aboriginal people outnumbered the first fleet. It also debunks the Makassan trader theory. https://t.co/SE31lLE8fJ
The WHO warned that most new Ebola cases in the eastern Democratic Republic of Congo are not linked to known patients, suggesting the outbreak may be two to four times larger than official figures indicate https://t.co/81MCV19wD9
"COVID-19-attributable neurological years lived with disability reached 30 to 40 years in adults..
the prevalence of cognitive impairment remained at 19.1% among individuals with mild to severe COVID-19 infection 2 years postinfection..
These disorders are structurally associated with whole-brain or region-specific atrophy..
COVID-19 patients would have unrecovered atrophy for global brain and specific brain structures after long-term follow-up, which is a typical sign of brain aging.
In addition, RNA-seq analysis of 54 postmortem brain samples revealed that the COVID-19 brain was enriched for aging pathways..
In this study based on the genetic data [of 5,779,391 participants],..we found that advanced COVID-19 causally increased the risk of aging for the total brain."
Protect your brain, please.
'Genetic evidence that advanced COVID-19 accelerates longitudinal brain atrophy: A Mendelian randomization study'
https://t.co/K1XkrUCmhI
I know. I'll post this and no one will see it or share it.
It's just the rolling annual total of NHS England Staff dying.
The media won't mention it
The government will stay silent about it
Doctors will pretend it's not real
But it's real.
Tell me:
When did the pandemic end?
"For me, one of the book’s most memorable analogies is its comparison of COVID-19 to syphilis, known as the “great imitator” for the variability of its symptoms and adverse effects." @EstermanAdrian
"SARS-CoV-2-encoded genomes (entire or fragments) and proteins have been detected in different brain regions of infected persons..
Even in the absence of active viral replication, microglial activation, dysregulation of neural cells, infiltration of T-cells and monocytes into the brain parenchyma, induction of inflammatory response by cytokine production and blood–brain barrier (BBB) disruption have been reported..
These findings suggest that the mere presence of virus-encoded genomes or proteins in the brain might activate neuroinflammatory responses..
[This study indicated that] neuropsychiatric impairments during SARS-CoV-2 infection might be driven by IL-6 mediated effects that increase MAO (monoamine oxidase) expression and activity."
SARS-CoV-2 genomes or proteins are thought-stopping agents.
'Immunometabolism perturbations in post-COVID-19 condition: interleukin-6 and monoamine oxidase interactions drive neuropsychiatric syndromes'
https://t.co/3RPBdTSYuk
The World Can No Longer Ignore Bioterrorism As A Threat - my commentary on Trojan Horse methods that we are ill-equipped to detect and prevent. @ndtv#insiderthreat#DIYbio#Reedley https://t.co/5uGsKErwql via @ndtv
Recently there is a study of Long Covid in China.
Scientists utilized cryo-electron microscopy to examine myocardial biopsy tissue from long COVID patients and found severe damage to the mitochondria within the cells. This organelle impairment cannot be detected through routine examinations.
https://t.co/EbS5liUQC6
One of the greatest pandemic success and failure stories you’ve never heard:
Victoria, Australia funded 111,000+ hospital-grade air purifiers—enough for every public primary and secondary school classroom.
Chief Health Officer Brett Sutton kept his word.
Top-of-the-line HEPA units. Distributed. Installed. Paid for.
Then what happened?
Teachers unplugged them.
Turned them off.
Some even sold them on eBay.
No maintenance plan.
No accountability.
No training.
No reinforcement.
A public health miracle… wasted by neglect.
Let this be a case study:
Even the best tech fails when people don’t understand, don’t comply, or don’t care.
Facts c/o @alijzimmerman
It's been a pleasure collaborating with the team at Altus on their Hero #mask, which works by #UVC sterilisation - a very novel concept for masks. The first paper on comfort and heat stress out now. @jljcolorado@majumdar_suman@sameo416@masknerd https://t.co/sToCa8jkHy