Mdh Aziz

Pediatrician at heart. Pediatric Nephrologist in the learning..

[IPNA Ped Nephrology @IPNA_PedNeph]

💡IPNA Journal Club – Read the Article Summary to Prepare 👉 https://t.co/tqstkfC1JB

📅 July 30 | 🕒 3 pm CEST
📌Zoom
📝Free registration: https://t.co/LnSqyswozK

#pedneph #learning

[Mdh Aziz @MdhAz09]

Crescentic GN in children. A Systematic Review!

[Srinivasavaradan @kiddo_kidney]

3/
This IPNAJC we will be discussing a recent systematic review- Etiology, Clinical Profile, and Outcomes of Crescentic Glomerulonephritis in Children: A Systematic Review.

Doi: 10.1007/s00467-024-06521-3

[Nephrology Journal Club @NephJC]

T3a 📌So what was the conclusion?#NephJc
🔑Felzartamab demonstrated an acceptable safety and side-effect profile with potential therapeutic benefit in AMR occurring 180 days of transplantation

[Mdh Aziz @MdhAz09]

@NephJC #NephJC Maybe Felzartamab may continue to have its effect even at the lower levels once the rejection is controlled...

[Nephrology Journal Club @NephJC]

T1c 🔬The molecular score for AMR using the Molecular Microscope Diagnostic System (MMDx) was used here. The MMDx project measures gene transcription on a graft biopsy, using algorithms to generate a report. #NephJc
🔗https://t.co/AoGGpP4Q4D

[Mdh Aziz @MdhAz09]

@NephJC @KajareeG #NephJC
Hello everyone, Madiha from Pakistan here

[Mdh Aziz @MdhAz09]

@NephJC #NephJC Could this be the AI of AMR? 🤔🤔

[Nephrology Journal Club @NephJC]

Antibody-mediated rejection in kidney transplant or a puzzle nephrologists trying to find the missing pieces

Could CD38 and felzartamab be the 🗝️? Too early to say! (get it? ph2📷)

Read #NephJC comprehensive summary by @KajareeG and @MdhAz09

https://t.co/v9mVxuIand

[Mdh Aziz @MdhAz09]

@nephromythri Many many congrats! Here's to more feathers in your cap 🥳🥳🥳

[Mdh Aziz @MdhAz09]

@NephJC #NEPHJC better physician education and awareness first

[Mdh Aziz @MdhAz09]

@NephJC #nephjc compliance always questionable with increased pill count

[Mdh Aziz @MdhAz09]

@NephJC #nephjc absence of proteinuria in inclusion criteria seems a substantial miss, what do you all think? with CKD still being in

[Mdh Aziz @MdhAz09]

@NephroSeeker #nephjc yessss!

[Mdh Aziz @MdhAz09]

#NephJC Hello everyone, Madiha from Karachi, Pakistan here

[Mdh Aziz @MdhAz09]

@NephJC @KajareeG Hello @NephJC and @KajareeG

[Nephrology Journal Club @NephJC]

🌟In med school and in practice as well, we are overwhelmed by the number of patients with hypertension and the various anti-hypertensive drugs!
🏅Before diving into tonight’s #NephJC, take a look at the article itself
https://t.co/8pp36PdkOJ

[Mdh Aziz @MdhAz09]

@IPNA_Congress February 19-23, 2025

[Jonny Wilkinson @Wilkinsonjonny]

There are 5 classes of diuretics we can consider.

You don’t have to just use furosemide! Everyone’s favourite loop…

Let’s use our physiology and pharmacology knowledge to combine some of them, to achieve good natriuresis as well as diuresis👍👏🤷‍♂️

[Sanjeev Sethi @SethiRenalPath]

Teaching subepithelial deposits (humps).

1) Infection-related GN (top panel)
2) C3 glomerulopathy
3) Proliferative GN due monoclonal Ig (bottom panel)
4) Lupus (Autoimmune) GN

Humps likely reflect complement.

Subepithelial location prevents removal & humps persist a long time.