Enrico Klotzsch

T-cell activation, Super-Res Microscopy, Mechanical Forces, Immunotherapy, Traction Force Microscopy

[Carmelo Ferrai @CarmeloFerrai]

👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽

[Enrico Klotzsch @MechanoImmunLab]

@MEAM_Penn @ArratiaPaulo Thanks for hosting me throughout the last 2 days. It been very exciting to meet @MEAM_Penn faculty and students.

[Carmelo Ferrai @CarmeloFerrai]

Mechanotransduction and how regulates lymphocytes in immunotherapy is what @MechanoImmunLab is presenting right now @Nano4Mech very exciting story!

[Dimitrios L. Wagner @dlwagner13]

New #preprint from the lab: using the CD3-zeta gene as an integration locus to redirect T and NK cells with CARs 🎉

Great work by led by @jonas_kath!

Following @j_eyquem TRAC approach, we ventured for an alternative locus suitable for more cell types.

https://t.co/LnA6SrRFsJ

[Enrico Klotzsch @MechanoImmunLab]

@CarmeloFerrai @Vogel_Lab @LabOxenius @MortezaAramesh @MichaelLDustin @HFSP @snf Hey Carmelo glad you like the story - looking forward to discuss potential collaborations!

[Gita Naseri @GitaNaseri]

How is Salmonella prepared for efficient host cell invasion? Read more about the dynamic interplay between # Bacterial Flagellum and #SPI-1 during the Salmonella infection cycle in a recent work of our group @Salmo_Lab, @DoaaOsamaSaleh in #PLOSPathogens https://t.co/pSZwhoLn2D

[Dimitrios L. Wagner @dlwagner13]

Reshaping breast cancer's collagen matrix improved T cell infiltration and tumor control in mice.
Could an anti-DDR1 mAb be the next weapon in our immunotherapy arsenal against solid tumors?
@MechanoImmunLab & I discuss the exciting findings by Sun et al @Nature 2021.

[Enrico Klotzsch @MechanoImmunLab]

Finally its online ! together with @Vogel_Lab @LabOxenius @MortezaAramesh special thanks to @MichaelLDustin financial support from @HFSP @SNF Nanoconfinement of microvilli alters gene expression and boosts T cell activation https://t.co/TXF58h7H63

[Enrico Klotzsch @MechanoImmunLab]

My first coverart :) #MyACSCover
@ACS4Authors
#SingleMolecules #Superresolution #proteomics https://t.co/t5XXGXwCwD https://t.co/MGr1t8BF7a

[Francesca Bottanelli @Fran_Bottanelli]

Point 2. Unless you are German...

[Enrico Klotzsch @MechanoImmunLab]

Our collaborative work in a newspaper 💪 @schuetzlab @huppalab #immunology #mechanobiology Entscheidende Zerreißprobe: Wie T-Zellen Krankheitserreger erkennen https://t.co/iwmyvGZXtY

[Enrico Klotzsch @MechanoImmunLab]

@Fran_Bottanelli Thinking of sneaking in over the fence 😋 !

[Enrico Klotzsch @MechanoImmunLab]

@SulianaManley @tatjana_kleele @timoHrey @jutziwin @SofiaZaganelli @Dora_Mahecic @WaiLabinParis1 Wow what an amazing paper ! Foundation to research towards Mitos role in many different functional aspects. Big congrats 🎉

[Enrico Klotzsch @MechanoImmunLab]

Our collaboration on T Cell forces: #singlemolecule #FRET to quantify forces by individual TCRs during #Tcell activation: pN-forces act laterally. SLB fluidity matters! #Schuetzlab, #Huppalab #Stockingerlab ! https://t.co/YZEZXOC3ql

[FiolkaLab @FiolkaLab]

Cancer cell migration imaged with isotropic subcellular resolution. Thanks to Jackson Petroll for the great rendering of our data!

[Enrico Klotzsch @MechanoImmunLab]

@Ti_Sapph @christlet @HenriquesLab „After asking everyone in the biology department I finally found some fixed cells as an application.“

[Einstein Foundation @Einstein_Berlin]

Viola Vogel @Vogel_Lab, Bioingenieurin @ETH, erforscht als Einstein Visiting Fellow @BIH_Innovations @ChariteBerlin die mechanischen Kräfte in Zellen. Im Podcast teilt sie ihr Nano-Wissen wie ihre Sicht auf's große Ganze: #Pandemie, #Politik & #Forschung ➡️https://t.co/f2rdkhUazV

[Enrico Klotzsch @MechanoImmunLab]

Our new paper on: Nanoconfinement of Microvilli Alters Gene Expression and Boosts T cell Activation. together with @Vogel_Lab @LabOxenius funding from @HFSP . https://t.co/DCrZuivx97

[Enrico Klotzsch @MechanoImmunLab]

our latest paper together with researchers in Australia: Nuclear Leukocyte Immunoglobulin-like Receptor A3 Is Monomeric and Is Involved in Multiple Layers of Regulated Gene Expression and Translation https://t.co/khbMH6s3W2

[Enrico Klotzsch @MechanoImmunLab]

@RetoPaul @coral_garzon @Dunn_Lab @Stanford @aaandmoore @Derpology Please send me an email so we can plan a brief meeting - I got a LLSM and a keen interest in mitochondria ! [email protected]