Melander Lab

Antibiotic adjuvants, biofilms and all things bacterial resistance | student run

[OBC @OrgBiomolChem]

Alexander Horswill @Horswill_Lab, Christian Melander @MelanderLab & co @CUAMCImmu_micro @NDscience report a structure activity relationship study of 3,4′-dimethoxyflavone for Staphylococcus aureus ArlRS inhibition in our latest issue

Read the paper here🔽
https://t.co/MNmSGYnmdM

[Melander Lab @MelanderLab]

Congratulations to Annie and Ansley! Overcoming intrinsic resistance in gram-negative bacteria using small ... https://t.co/tgp0D0hjMC

[Melander Lab @MelanderLab]

Congrats Haoting and everyone who contributed! 6-Bromoindirubin-3′-oxime derivatives are highly active colistin adjuvants against Klebsiella pneumoniae - now published in RSC Medicinal Chemistry https://t.co/bRfpjynqeI

[Melander Lab @MelanderLab]

Great job Ansley! Highlighting the 2020–2021 ACS Division of Medicinal Chemistry Award Winners https://t.co/BuWJCElm5Y

[Melander Lab @MelanderLab]

Development of small molecules that work cooperatively with ciprofloxa... https://t.co/zX4t1Lamf5
Congratulations Katie and everyone who contributed!!

[Melander Lab @MelanderLab]

Synthesis, Stereochemical Confirmation, and Derivatization of a Clerodane Diterpene That Sensitizes Methicillin‐Resistant Staphylococcus aureus to β‐Lactam Antibiotics https://t.co/ATxHkshjPz
Congratulations Michael and everyone who contributed!! @QuaveEthnobot

[Melander Lab @MelanderLab]

We are so happy to have our rising fourth year, @ansleynemeth, back from her 5 week internship in Boston! She was working with Dr. Eddie Geisinger at Northeastern University. She was primarily working on Tn-seq with some of the compounds she synthesized.

[ACS Division of Medicinal Chemistry @AcsMedi]

Congratulations @ansleynemeth! Looking forward to recognizing the great work of our fellowship awardees!

[Melander Lab @MelanderLab]

Congratulations to our student @ansleynemeth for receiving the @AcsMedi predoctoral fellowship! Thanks to ACS MEDI Division and @genentech for sponsoring this award. We are excited for Ansley for this opportunity!

[Melander Lab @MelanderLab]

Melander Lab 2021 coming at you live! #NewProfilePic

[Melander Lab @MelanderLab]

Congratulations to Dr. Karlie Cox for successfully defending her thesis!

[Melander Lab @MelanderLab]

A beautiful column being run by one of our second years!

We hope she gets a pure product!

[Bill Wuest @wmwuest]

Congrats to @AnaCheng06 of the @Wuestlab for making the most of the quarantine & writing a book! Thanks to @ACSPublications for inviting us to write the inFocus book Antibiotics intended to be a 5-hr course for senior UGs/1st yr grads. @laneygradschool https://t.co/RSRJ1OhfY4

[Daniel V. Zurawski @DaZtrain]

COVID patients and A. baumannii.
Wish I could say I am surprised.
But I am not.

Increase in Hospital-Acquired Carbapenem-Resistant ... https://t.co/T5JpgSTpis via @CDCgov

[Melander Lab @MelanderLab]

Latest paper from the lab. Congrats Alex, Sam, Pat and Orry! Thanks to @ErnstLabUMB
A scaffold hopping strategy to generate new aryl-2-amino pyrimidine MRSA biofilm inhibitors - now published in RSC Medicinal Chemistry https://t.co/k7MkOq85Tl

[CAIN @cain_amr]

"Antibiotic Resistance: A Matter of Time." Kick off World Antimicrobial Awareness Week 2020 with this powerful video from @FT. https://t.co/SkNifkvnxp

[Melander Lab @MelanderLab]

Two papers from the lab included in this collection!

[ChemMedChem @ChemMedChem]

To recognize the WHO's World Antimicrobials Awareness Week (18-24.Nov #WAAW2020), our Hot Topic this month is #Antimicrobials, free to read for the rest of the year: https://t.co/L0YYaLl6az #drugdiscovery #medchem

[Dr. Cassandra Quave🌿⚕️ @QuaveEthnobot]

To all of my #antibiotic discovery peeps interested in #naturalproducts -- I'd love to brainstorm ways to leverage this work to fill the #antibiotic pipeline with more #plantbased scaffolds! #chemicalbiology @MelanderLab @whiteleylab @DaZtrain @gerryiidr @eric_brown_bbs + more🌺

[Dr. Cassandra Quave🌿⚕️ @QuaveEthnobot]

New paper from #QuaveLab!! I'm so proud of this one! Our team worked tirelessly on this for >1 year to undertake the 1st major assessment of antibiotic compounds from plants!

Ethnobotany and the Role of Plant Natural Products in Antibiotic Drug Discovery https://t.co/GvjgGRqbWw

[Wiley Chemistry @Wiley_Chemistry]

Call for papers on Antibacterial Drug Discovery.

Click here for more information: https://t.co/z2ARp9G0HR