What comes to mind when our #PerutzAlumni think of their time at the Perutz? 💭
For @MerritRomeike, who completed her PhD in the lab of @chribue in 2022, it's all about the supportive community 🎓✨ Watch her share her thoughts and discover what she’s up to now! #AlumniStory
Excited to share our manuscript about IGNITE (Inference of Gene Networks using Inverse kinetic Theory and Experiments) – a machine learning framework that infers Gene Regulatory Networks (GRNs) from unperturbed single-cell RNA sequencing data and predicts gene perturbations!
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🚨Interested in human development, organoids and pluripotent stem cells? Our lab - @VallierLab - is looking for a PhD student through the IMPRS graduate program to work with us at the fantastic @MPI_MolGen in Berlin! Apply by Jan 5th, 2024! Amazing science & supervision!👇
How do stem cells fight against viral infections? In @emboreports the @chribue lab with @MerritRomeike show that the gene network regulating the pluripotent cell state directly controls Irf1, a key gene of the innate immune response. Read more: https://t.co/UnEIGn8aj4 @univienna
@Sc_Ninjas Any tips on how to quantify cell to cell variability within one cluster? Similar to what Kolodziejczyk et al (2015) did with CV^2 and a running median, but I wonder if there are more specialised approaches. Thanks!
I am very excited to share part of my PhD work with Christa Buecker @chribue at the @MaxPerutzLabs: Stem cell specific interferon stimulated gene expression is regulated by the formative pluripotency network through IRF1 https://t.co/3wOIh7xjvL 1/8
The same transcription factors that are establishing formative pluripotency also control expression of antiviral genes through Irf1 and thereby keep the cell state intact and safe. 7/8