Microbiological, molecular biological, cell biological and immunological laboratories; interface for Research and Development; cell bank and phage analytics
Remember that you can have access to all the lessons (also in pdf) of the course Trends in Microbiology by Twitter in the Wakelet-SEM page #EUROmicroMOOC@FEMSTweets
https://t.co/DRiFLqc5Y8
The world first prospective multicentric, randomised, single blinded and controlled clinical trial of #phage therapy ever performed according to GMP and GCP ended in 2017. Phage community is looking forward to see the results.
#MicroMol#EUROmicroMOOC https://t.co/oNLzLDKgKN
The #phage phiX174 was the first "organism" to have its entire nucleotide sequence determined, a feat that was accomplished by Frederick Sanger and colleagues in 1977.
#MicroMol#Tentamus#Laboratory#EUROmicroMOOC https://t.co/XF9EknDlRw
In 1943 Luria and Delbrück in their famous experiment using #phage T1 and E. coli cultures proved that genetic mutations arise in the absence of selection, rather than being a response to selection.
#MicroMol#Tentamus#Laboratory#EUROmicroMOOC https://t.co/iHYABuwlQe
The genetic material is so densely packed in viron heads that a preassure of tens of atmospheres is exerted on the inner capsid walls.
#MicroMol#Tentamus#Laboratory#EUROmicroMOOC https://t.co/gmYn7g30qf
#Phages are so specific to their hosts that they can be used for strain differentiation within one species using a method called phage typing.
#MicroMol#Tentamus#Laboratory#EUROmicroMOOC https://t.co/MxlfMDAcxU
"Virus burst size” is a term describing the number of released virions from single bacterial cell after lysis. Usually about 100 - 1000 phages are produced in a single cell.
#MicroMol#Tentamus#Laboratory#EUROmicroMOOC
https://t.co/8ajEJg2ag8
To avoid overkilling of their host #Phages communicate via small proteins that are discharged during lysis of the #bacteria . With increasing concentrations phages become lysogen instead of lytic, what helps stabilizing the bacterial culture.
#MicroMol#Laboratory#EUROmicroMOOC"
Researchers have found that some #Phages can communicate. They produce and sense chemical signals and thus can decide whether to kill or keep their hosts alive.
#MicroMol#Tentamus#Laboratory#EUROmicroMOOC https://t.co/Z7cWqP8vJO