Zoe Mills

[Evelína Buxbaumová @berryciu7x]

My outlook on SSRI use in the pediatric population, part 1:

1. Population-level efficacy does not establish individual benefit
Objection: "Some children with severe depression or OCD benefit substantially from SSRIs. Wouldn't prohibiting them deny those children effective treatment?"

My response:

Which children? How many? How substantial is the benefit? And how can we identify them beforehand?

We currently cannot reliably predict which child will:
- Experience substantial improvement.
- Experience little or no meaningful benefit.
- Develop serious adverse reactions.
- Experience persistent post-treatment dysfunction.

I'd also like to challenge the use of overall response rates because they include improvement that may occur through placebo effects, spontaneous recovery and other influences.

And I would also like to refer to the 2025 TADS reanalysis - https://t.co/YZYS8HCIyz -, which questioned aspects of the original efficacy reporting and identified additional suicide-related adverse events.

Importantly, I must emphasize that the severity of a psychiatric condition does not reliably establish that a particular child will benefit from a particular drug.

Severe psychiatric "illness"* increases the importance of finding effective care. It does not automatically make an SSRI necessary, safe or effective for that individual.

*The severity of a psychiatric diagnosis—or, more precisely, the severity of the psychological symptoms, distress and functional impairment on which such diagnoses are primarily based—increases the importance of providing effective, appropriate care.

However, psychiatric diagnostic categories are generally defined through clinical observations and symptom criteria, rather than through the identification of a specific, uniform biological pathology.

The same diagnosis may encompass individuals with substantially different underlying mechanisms and contributing circumstances.
- https://t.co/Flo7qkGiJZ -
- https://t.co/tqgR4eS7SW -

Consequently, the severity of a child's symptoms does not establish that a particular medication is biologically necessary, likely to be effective, or acceptably safe for that individual.

Nor does it eliminate the need to investigate psychological, social, developmental, environmental and medical factors that may contribute to their difficulties.

The possibility that some children benefit cannot, by itself, justify exposing others to serious risks when we cannot reliably distinguish those groups beforehand.

[Evelína Buxbaumová @berryciu7x]

My outlook on SSRI use in the pediatric population, part 2:

Benefits and harms must be assessed over comparable time horizons

Objection: "If SSRIs produce significant improvements in depression or OCD symptoms, doesn't that justify accepting some risk of adverse effects?"

My response:
Not necessarily. The magnitude, duration and consequences of both benefit and harm must be considered.

I urge everybody to question whether several months of symptom improvement could justify exposing a child to the possibility of decades of:

Genital anesthesia.
Sexual anhedonia.
Profound generalized anhedonia.
Emotional blunting.
Cognitive difficulties.
Impaired intimate relationships.
Other persistent or life-altering consequences related to the endocrine, heart health, metabolic, and other negative effects of these drugs.

Evidence regarding sexual dysfunction and emotional numbness in children during treatment.: - https://t.co/FA5Eaw2IuM -

Human evidence of lasting sexual effects following childhood exposure in women, (fewer men partook in this study, the effects on the men were not deemed significant):
- https://t.co/K4HyUFCtjL -

Pirani et al. (2025): Persistent Genital Hypoesthesia Among Former Antidepressant Users: - https://t.co/ZBbYxN1XNs -
- Crucial limitation: This was a selected sample of sexual and gender minority young people, encompassing both minors and adults. It cannot establish a 13.2% PSSD prevalence among all antidepressant users or isolate the risk attributable to exposure during childhood (which could sadly be much higher). -

All before they even fully develop their sexual/reproductive functioning, or understand these consequences. All before they can ever meaningfully consent.
This decision, which can be life-altering for a certain number of people, in a wide number ways -neither of which can we currently estimate or understand - is made for them.

Short-term clinical improvement must not be treated as equivalent to overall lifetime benefit, particularly when the potential harms may affect fundamental aspects of human functioning.

[Evelína Buxbaumová @berryciu7x]

Deeply concerning

https://t.co/OGkye0G08J

[Evelína Buxbaumová @berryciu7x]

Pfizer fraud findings. History repeats itself.

https://t.co/9mJofklpCU

[Evelína Buxbaumová @berryciu7x]

"Is it fair and honest to describe PSSD as permanent?"

Persistent harm must be understood in practical, patient-centered terms

Objection: "There is no proof that PSSD is biologically irreversible. Isn't describing it as permanent scientifically inaccurate?"

My response:
I am using permanent in a practical, patient-centered sense. There are currently no established treatments. We do not know how long it might take for treatments to start to emerge.

I am not claiming that researchers have established that every underlying biological abnormality is impossible to reverse.

But a condition that oftentimes naturally persists indefinitely, doesn't have clear biomarkers, and for which there are no treatments deserves to be taken seriously.

To put it concisely:
-A condition that persists for decades may be functionally permanent.
There is currently no established intervention that reliably reverses PSSD.
Reliable long-term recovery rates remain unknown.
Some people may live with the condition for the remainder of their lives.-

If someone develops PSSD at 40 and experiences it until death, the condition was permanent in their lived experience.

The theoretical possibility that scientists might eventually discover a treatment does not restore the years they have already lost.

Patients should not have to demonstrate molecular irreversibility before decades of treatment-associated disability are recognized as potentially lifelong harm.

[HS Author PA @author_hs31181]

Michael Jackson, Taylor Swift, Adele, Beyoncé, Rihanna, Bruno Mars, The Weeknd, all this beautiful music, & I can't feel any of it anymore. PSSD has taken away my ability to enjoy music and the emotions that used to come with it. I feel emotionally disconnected from everything.

[The Telegraph @Telegraph]

"I don’t just think antidepressants are overprescribed, I’m not convinced they’re useful at all. Antidepressants don’t rectify a chemical imbalance or any other biological process, as people were led to believe; they numb emotions"

"The question is, is this useful, and how harmful are they?" 👇
https://t.co/L4OybfIwGS

[Zoe Mills @MillsZoeHarber]

@thairkassam Utter BS

[Christian Gal✝️🇬🇧 ✡️ Catholic Zionist @AnnabethUnbound]

Friendly reminder that when Russell Brand was grooming, raping (because I don't believe 16 year olds can consent to sex with men in their 30s) and drugging the school girl Peaches Geldof, within two years or so, her younger sister Pixie would fall prey to his bestie Noel Fielding. 🤢

Pixie Geldof was 16 and studying her GCSE's.
Noel Fielding was 33.
Peaches Geldof was 16-17 Russell Brand was 29.

Fielding and Brand abused those girls.
And they got away with it.

[Matthew Baszucki @matthewbaszucki]

SSRIs are a scam. They barely do anything.

They improve symptoms 50%, compared to 40% from a placebo. And they only boost mood an average ~2 points on a 52-point evaluation (based on meta-analyses of RCTs, the best data we have). You'd get more benefit from a 15-minute walk outside.

But you can get permanent genital numbness and anhedonia from these medications. They destroy lives.

The pharmaceutical industry has been poisoning us over and over, with medication after medication, for generations.

Keto & metabolic therapies are the future of mental illness treatment.

I'm not completely anti-medication. Some can be helpful in certain cases. But these SSRIs are sick and evil.

[Jorge Hernández PSSD @redpavement]

Don't let your psychiatrist groom you

into taking psychiatric medication

...

It can permanently damage your brain

[Sky News @SkyNews]

A TV worker confided in comedian Lucy Beaumont that he was asked to take young women to David Walliams' dressing room, she tells @CathyNewman. Beaumont says she later found one of the women and offered help. Sky News has contacted Walliams' representatives about this allegation.

[Jorge Hernández PSSD @redpavement]

just a few SSRI pills can fuck you up for life.

Becareful

Better to avoid them

[Dr Joanna Moncrieff @joannamoncrieff]

In relation to my ‘Ask the Expert’ section about antidepressants in the Telegraph today, I will be answering readers’ questions live online from 11am. Just go to the Comments section. @Telegraph @flint_books. https://t.co/dl8lzJGmUc

[James Spiro @JamesSpiro]

Jonathan Ross: “The comedy awards is 15 years old… and like most 15-year-olds, it's drunk, it's unpredictable, and it's probably going home with David Walliams.”

Everyone knew. Just like they did with Russell Brand.

[Dr. Drew @drdrew]

Then, after the break, Vanderbilt senior Lauren Friedman is here to talk about Post-SSRI Sexual Dysfunction and why UK regulators now officially warn patients about it, but the FDA still does not. She says an antidepressant took away her sexual and emotional function, and even after stopping, she still struggles to feel joy, attraction, or even love for her own family. Find more on Instagram at @StolenYouthMovement.

[HS Author PA @author_hs31181]

PSSD is a man-made tragedy linked to SSRIs, a crime against humanity. It's a man-made evil happening right in front of us, yet people are silently watching it unfold. We're left on our own, desperately appealing for a cure.

[Normal Island News @NormalIslandNws]

No one will ever figure out how this lad whose dad took him to brothels when he was still in school grew up to be rapist. Where were the signs?

[Naomi Rohatyn @omibaloney]

A man cheated on Halle Berry. A man cheated on Natalie Portman. A man cheated on Beyoncé. A man cheated on Emily Ratajkowski. A man cheated on Shakira. There is literally no level of physical attractiveness (or success for that matter) that “saves” a woman from being cheated on

[Jorge Hernández PSSD @redpavement]

People need to know that psychiatric medication

can cause

permanent castration