Maureen Obure

....just the ordinary girl next door..mummy | daughter | lover | doctor | friend | sister | Forensic Pathology enthusiast | Human ❤💞

[Maureen Obure @MoObure]

@fnoluga As a consultant physician, this is the last thing you should support knowing the risks you are exposing our HCWs and citizens for. This is so sad. So disappointed.

[Vera Ghali, MD @veraghali]

Wishing you my friends a happy day ✨️
"Time is a River Without Banks"
Marc Chagall

[Seneca the Younger @SenecaQuote]

- Cicero

[Words of Wise | Mindset Coach @Wordofwise_]

“We can easily forgive a child who is afraid of the dark; the real tragedy of life is when men are afraid of the light.”

— Plato

[Dr Motasem Al-Gradey @Mota55em]

🌸Lymphocytes “Flower Cell”🌸

✅ A lymphocyte with a nucleus resembling flower petals.
✅ Most commonly observed in Adult T-cell Leukemia/Lymphoma (ATLL), which is associated with HTLV-1 (Human T-lymphotropic virus type 1) infection.
✅ Considered a hallmark feature supporting the diagnosis of ATLL.

👉 Therefore, “Lymphocyte Flower Cell” = a Lymphocyte with a flower-like nucleus (most often seen in ATLL caused by HTLV-1 infection).

🌸Morphology
✅ Cell size: Medium to large, larger than small mature lymphocytes.
✅ Nucleus: Polylobated/petaloid, with 3–6 lobes and deep indentations resembling petals (not shallow grooves like cerebriform nuclei).
✅ Chromatin: Coarse, hyperchromatic; nucleoli usually inconspicuous.
✅ Cytoplasm: Scant to moderate, sometimes mildly basophilic, with smooth borders.
✅ Other findings: Anisocytosis; increased numbers of flower cells in cases with lymphocytosis.

🌸Pitfalls & Differential Diagnosis (DDx)
🍀Sézary cell (CTCL/Sezary syndrome): Cerebriform nucleus with fine, shallow grooves; not lobulated.
🌺 Reactive/atypical lymphocyte (e.g., EBV/CMV): Large cells with abundant cytoplasm that often “embraces” RBCs; nucleus oval/irregular but not lobulated.
🌹Monocytes/Polymorphonuclear leukocytes: Presence of granules and granulocytic chromatin pattern distinguish them from lymphocytes.
💐Others: Occasionally, reactive multilobated lymphocytes may be seen, but when present in large numbers with clear petaloid shapes, ATLL should be strongly considered.

🌸Common Clinical/Laboratory Associations in ATLL
✅ Hematology: Lymphocytosis
✅ Clinical features: Skin rashes/lesions, lymphadenopathy, hepatosplenomegaly
✅ Biochemical findings: Hypercalcemia, elevated LDH
✅ Systemic involvement: May affect bone, skin, and other organs

[Dr. Arkadip MD @pathognosis22]

#Grossing essentials! Organ normal dimensions and weights #pathresident #pathology #grays #anatomy

[Robert Griffin III @RGIII]

UPDATE:

If you love Michael Jackson, you will LOVE this Movie.

The Music.
The Wardrobe.
The Design.
The Acting.

Jaafar Jackson was born to play this role.
Nia Long was POWERFUL.
Coleman Domingo was terrifyingly incredible.

#MichaelMovie is a celebration of the King of Pop.

[MV Chandrakanth @ChandrakanthMv]

MMR IHC Interpretation – Super Simple Quick Algorithm 🔥

Test the 4 proteins → All present? → pMMR (good)

One or more missing? → dMMR (needs attention)

Then follow the exact pattern of loss:

MLH1 & PMS2 lost (most common) → Check BRAF & MLH1 methylation

MSH2 & MSH6 lost → Likely Lynch
Only MSH6 or only PMS2 lost → Possible Lynch

Weird single losses (MSH2 alone or MLH1 alone) → Not possible, recheck!

Key rule: Always read MMR as pairs, not single markers!

(MLH1 protects PMS2 • MSH2 protects MSH6)

Saves time in daily practice. Save & share!

#MVOnco #Oncology #Pathology #MedEd

[WebPathology @WebPathology]

Update in #HemePath - Progressively transformed germinal centers. 20 images. Check it out on the website under Lymphadenopathies - II.

[Vikram Deshpande @Vik_deshpandeMD]

when not to use the term)New paper alert! Our work on colonic intramucosal adenocarcinoma (when not to use the term) is now online in @JClinPath ahead of print. Quick video walkthrough of the key points.

#PathTwitter #GIPath #IMCA #Pathology

[Cytopathology @CytopathologyJ]

🙋‍♂️What is the most likely #cytopath diagnosis of an enlarged #lymphnode in a boy showing:
- reactive lymphoid cells
-eosinophils forming microabscesses
-Warthin-Finkeldey giant cells
-scattered eosinophils in the background?
#CytoJ ⬇️

[Maureen Obure @MoObure]

@Ugochukwu96_ Coming to America

[George T. Diano @georgediano]

While other MPs were running to the Parliament basement for safety, Edwin Sifuna was outside stopping rogue officers from shooting unarmed Gen Z protesters. Dear Young Blood, his Name is EDWIN SIFUNA. Never forget that!!!

[Pauline Njoroge @paulinenjoroge]

Winnie Odinga is who she thinks she is 🔥🔥🔥

Brilliant, firm, articulate and very clear on what she stands for!

[WebPathology @WebPathology]

Additional images: Lymphoepithelioma-like Urothelial Carcinoma. Sheets, clusters of undiff. cells with syncytial appearance surrounded by lymphoplasmacytic infiltrate. Resembles nasopharyngeal lymphoepithelioma but lacks association with EBV or HPV. Pos for cytokeratins, GATA3.

[Lawrence Kitema @lawrencekitema]

A man died of hunger, but food was served at his funeral. When you're less busy, think about it.

[WebPathology @WebPathology]

Update in #ENTPath #Mediastinum - #Thymoma has been updated; 263 images, mostly new.

[Maureen Obure @MoObure]

@amooh001 Breaking Bad

[Dr Kamlesh Darji @DrKamleshDarji1]

Adenoid cystic carcinoma: Summary points for histopathologists. #SalivaryGlandpathology #PathX #Pathologists

[Maureen Obure @MoObure]

@DrKamleshDarji1 Whorling pattern. Meningioma