Another beautiful collaboration with the Lamb lab with mito imaging by @osman_lab .Work done by three brilliant PhD students -smFRET in intact mitos established by @RupaBanerjee17 and Vanessa Trauschke and biochemistry done by @NBertram90671 🥳🥳
How do cells assess mtDNA quality?
Local ATP and membrane-potential gradients reflect mtDNA integrity and drive intracellular purifying selection.
We introduce FAST, a scalable mtDNA QC assay in S. cerevisiae.
https://t.co/8M35ogdFWq
Congratulations to Nils for winning the poster prize at the EMBO|FEBS Lecture Course on Susan Lindquist School on Proteostasis in Espoo, Finland 🎊🎉😊🤗!!! @FEBS_Letters
Walter Neupert Symposium 2025! Congratulations to Prof. Dr. Nikolaus Pfanner and Prof. Dr. William Wickner on receiving this year's medal and to Soraya and Nils for giving the student talks!✨️❤️
Had the most fun time attending the 22nd @HorizonsMolBio conference in the beautiful city of Göttingen! Connecting with scientists and learning new things!✨️ Thank you @lifescimunich for the financial support!❤️
🚨 Preprint alert! 🚨
My first first-author manuscript is out on bioRxiv!
We developed a new method to monitor mtDNA quality control in yeast, and found that a functional respiratory chain is crucial for the process.
@osman_lab@SchmollerLab@hoerldavid
https://t.co/p1IQjrJy6n
🚀 Excited to share our latest work on Mrx6 and mtDNA copy number regulation, now available on @biorxivpreprint ! We uncover how Mrx6 and Mam33 interact with the Lon protease Pim1 to control substrate degradation. 🔬 Check it out here: https://t.co/jMAYrLoqUW #mitochondria#mtDNA
Always a fun time to celebrate a publication!🎊 If you haven't yet, check out our latest paper in which we characterise Dbi1, an open reading that helps mitochondrial inner membrane proteins such as Tim17 gain its disulfide bond!
https://t.co/Ezc6l9uAM4
#Dbi1#Tim17
New year and a new publication!🥳 Our latest research on Dbi1, an uncharacterised, open reading frame that acts as a novel oxidoreductase and assembly chaperone in the mitochondria is out now!! Thank you to @emboreports for publishing our hardwork!🥳
https://t.co/Ezc6l9uAM4
The family that makes and eats sushi together, stays together! The Annual Mokranjac Sushi Feast '24 was a wonderful time with past and present colleagues! Hearty conversations over food were very wholesome🥰🍣🥢
#sushi#AGMokranjac#teamwork