MooreLabSIO

Student-run twitter of the Brad Moore Lab @Scripps_Ocean & @UCSanDiego
Marine Natural Products Chemistry | Chemical Ecology | Biocatalysis

[Bradley Moore @BradMoore_SIO]

Vanadium-dependent haloperoxidase enzymes have always fascinated us @moorelabsio for their biosynthetic dexterity. We're delighted to finally share some beautiful structures in @BiochemistryACS https://t.co/Y9KoJMDgm4

[Bradley Moore @BradMoore_SIO]

Congrats Dr. Kate Bauman @kdbauman_ on your masterful dissertation seminar today at @Scripps_Ocean. It has been my pleasure joining you on your scientific journey! #proudPI

[MooreLabSIO @moorelabsio]

We’re so proud of our labmate!

[Scripps Institution of Oceanography @Scripps_Ocean]

Kate Bauman researched marine microbial natural products at Scripps w/ @moorelabsio, earning a PhD in #MarineBiology. She was awarded the Frieman Prize for her work detailing how a marine bacterium makes an anti-cancer molecule. 🌟 Now, Kate is headed to @Stanford as a postdoc!

[Nature Chemical Biology @nchembio]

Our June issue (https://t.co/OcCuuSeaIm) features a stunning array of octocorals, which the @EricSchmidtLab and @moorelabsio found were capable of producing their own terpenoids (https://t.co/vdJnmu4Qzx & https://t.co/StSizam00i).

[Bradley Moore @BradMoore_SIO]

Thrilled to share our latest @nchembio publication by @BurkhardtImmo @Tristan_enzymes @thePYTC that #octocorals biosynthesize powerful terpenoids and have been doing it longer than in plants. These primitive animals are remarkable medicinal chemists! https://t.co/FQ7xuZ7SGh

[Scripps Institution of Oceanography @Scripps_Ocean]

Scientists at Scripps, @usponline & @ucsantacruz have collaborated to discover & validate the enzymes responsible for production of guanitoxin—one of the most toxic & fast-acting neurotoxins associated with freshwater harmful algal blooms in lakes & ponds. https://t.co/ZF7GztgeCG

[Scripps Institution of Oceanography @Scripps_Ocean]

Learn more in this segment from @10NewsAarons on how Scripps scientist @BradMoore_SIO and team discovered how a deep-sea bacteria creates an anti-cancer molecule, which is currently in clinical trials to treat brain cancer. Via @10News https://t.co/g725K3q8Zf

[Bradley Moore @BradMoore_SIO]

Ten years in the making to demystify how the #glioblastoma drug candidate marizomib is made by marine bacteria. Congrats to @kdbauman_ @VikShende @techbiodd @RomoGrp_Baylor @TrivellaDBB @Scripps_Ocean https://t.co/HJwlmifM7B

[ACS Pressroom @ACSpressroom]

San Diego, the location for the in-person portion of the hybrid #ACSSpring2022 meeting, is also home to scientifically relevant wildlife. @VikShende and @ScienceSiren_ discuss their work at the @MooreLabSIO @Scripps_Ocean on local sea sponges: https://t.co/xns0YXcJdy

[Bradley Moore @BradMoore_SIO]

Great hanging with @moorelabsio at #ACSSpring2022. What a great looking group! The PI needs to step up his game however...

[MooreLabSIO @moorelabsio]

We’re excited to have several members at #ACSSpring2022 in San Diego this week! Come check out our talks and posters from @BradMoore_SIO @AprilLukowski @kdbauman_ @VikShende @ScienceSiren_ @BurkhardtImmo

[Bradley Moore @BradMoore_SIO]

Thanks #SeaSecrets and @UMiamiRSMAS for the invitation to share our work with you on Reading and Writing the Genetic Code of Marine Life to Cure Human Disease https://t.co/CMGxkRck7d

[Bradley Moore @BradMoore_SIO]

Moore lab reunion @GordonConf #MarineNaturalProducts Just missing @gt_vinny who ditched us to go whale watching. Replaced with the legend Bill Fenical. @Scripps_Ocean @moorelabsio

[Brittany @brittybirdie]

So many talented and inspiring women in science at Scripps! Check out this thread in honor of the #InternationalDayOfWomenAndGirlsInScience. 🌊👩🏻‍🔬💪🎉

[Bradley Moore @BradMoore_SIO]

Wonderful collaborating with you @RyutaTerada to tell the story of this fascinating #seaweed that was used historically as an anthelmintic in Japan, with the name “domoic acid” deriving from the word “domoi,” the Japanese name for Chondria armata

[Bradley Moore @BradMoore_SIO]

Happy to share how the #cyanotoxin aetokthonotoxin is made by toxic freshwater Cyanobacteria. Amazing enzyme work by @sanjoyadak90 @AprilLukowski Rebecca Schafer in @J_A_C_S https://t.co/yfGZo7fO9W

[Scripps Institution of Oceanography @Scripps_Ocean]

Low tides = great tidepooling opportunities! 🐙🐚 During a negative low tide this week, PhD students Anaí Novoa, @seaweedsista, @ScienceSiren_ & @oliviaspereira explored the #TidePools near Scripps, where they encountered nudibranchs, octopuses, crabs, and much more. 📷@erikjep

[Bradley Moore @BradMoore_SIO]

Many #naturalproduct compounds like #cannabinoids are made from ortho-quinine methides. @TrevorPurdy @AprilLukowski review the ways enzymes construct this versatile and reactive biosynthetic intermediate https://t.co/oOP5AFEnNJ

[Taylor Steele @taysteele_]

Very pleased to share my first, first-author paper! Domoic acid biosynthesis in the red #seaweed Chondria armata, out in PNAS today. Immensely grateful for all of our collaborators, especially @ChekanLab, @moorelabsio, and my amazing PI @BradMoore_SIO.
https://t.co/9CFpjuYVpc

[Chekan Lab @ChekanLab]

Very excited to have published our first paper in collaboration with @BradMoore_SIO and @kdbauman_ in @NatProdReports!

https://t.co/1i5RKrxowp