Morscher Lab - #PediatricCancerMetabolism

We elucidate #pediatric #cancer & #metabolism to tackle #childhoodcancer. #translation regulation. Raphael’s tweets _RJM. Join our fight @KispiZuerich @UZH_en!

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

𝐇𝐚𝐭 𝐭𝐫𝐢𝐜𝐤 𝐟𝐨𝐫 𝐜𝐡𝐢𝐥𝐝𝐡𝐨𝐨𝐝 𝐜𝐚𝐧𝐜𝐞𝐫: 𝐍𝐚𝐭𝐮𝐫𝐞 𝐚𝐫𝐭𝐢𝐜𝐥𝐞, 𝐜𝐨𝐯𝐞𝐫, 𝐚𝐧𝐝 𝐧𝐞𝐰𝐬 𝐟𝐞𝐚𝐭𝐮𝐫𝐞!
1) https://t.co/krtqEwQkS1
2) https://t.co/StZvIlYw0m
3) https://t.co/gY57eEyevv
I couldn’t be prouder of @sarah_cherkaoui and all the co-authors!

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

https://t.co/EFd9aC4SOv

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

Exciting highlight of the work of @sarah_cherkaoui and many colleagues including Josh Rabinowitz and Mike Hogarty @MorscherLab @Princeton @LudwigCancer @Nature

[Cancer Discovery @CD_AACR]

Dietary Polyamine Depletion Translationally Rewires Neuroblastoma https://t.co/onAesAd7v5
A #ResearchWatch summary of a recent study by Sarah Cherkaoui, Joshua D. Rabinowitz, Michael D. Hogarty, Raphael J. Morscher, and colleagues

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

@Princeton @LudwigCancer @ChildrensPhila @wenyun_lu @mcbride_matthew @RutgersU @EileenWhitePhD

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

𝐇𝐚𝐭 𝐭𝐫𝐢𝐜𝐤 𝐟𝐨𝐫 𝐜𝐡𝐢𝐥𝐝𝐡𝐨𝐨𝐝 𝐜𝐚𝐧𝐜𝐞𝐫: 𝐍𝐚𝐭𝐮𝐫𝐞 𝐚𝐫𝐭𝐢𝐜𝐥𝐞, 𝐜𝐨𝐯𝐞𝐫, 𝐚𝐧𝐝 𝐧𝐞𝐰𝐬 𝐟𝐞𝐚𝐭𝐮𝐫𝐞!
1) https://t.co/krtqEwQkS1
2) https://t.co/StZvIlYw0m
3) https://t.co/gY57eEyevv
I couldn’t be prouder of @sarah_cherkaoui and all the co-authors!

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

#childhoodcancer #neuroblastoma #university_of_zurich #childrens_hosptial_zurich

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

Thank you for highlighting this collaborative work!

[Princeton University @Princeton]

A joint University of Zurich and @Ludwig_Cancer study finds that a diet and drug combo could reverse malignancy to treat neuroblastoma, a rare but extremely aggressive pediatric cancer: https://t.co/Mg1vn3ee8D

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

🎗️ Just published in Nature! Excited to share our work on metabolism and translation regulation crosstalk in childhood cancer. We introduce a pro-differentiation proteome to cure!
🔗 Reprogramming neuroblastoma by diet-enhanced polyamine depletion: https://t.co/krtqEwQkS1

[nature @Nature]

Mouse studies show that depriving neuroblastoma of certain amino acids causes a switch in protein synthesis to suppress tumour growth and promote cell differentiation

https://t.co/PQwWYn588X

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

Super cool work - so much to learn from nature . . .

[Sorek Lab @SorekLab]

We discovered a new immune signaling molecule: N7-cADPR

N7-cADPR is produced by phage-stimulated TIR proteins. It activates a bacterial caspase, which then degrades essential proteins to curb infection

Preprint: https://t.co/0dzoyNP6t5

Congrats @FrancoisRousset & @IlyaOsterman

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

Exciting science @EACRnews #Bilbao & honor to contribute with our latest work: Reprogramming Neuroblastoma by Diet-Enhanced Polyamine Depletion. 💡 https://t.co/uC5s1kMaPw💡
@sarah_cherkaoui @UZH_en @MorscherLab https://t.co/w7BW5tn9z2 #PediaticCancerMetabolism

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

Congratulations Ines, Gillian and Sarah! pleasure working with @debocklab !

[Muscle Cell News @musclecellnews]

Researchers led by Drs. Inés Soro-Arnáiz & Gillian Fitzgerald reported that GLUD1 prevents ⚔️ deleterious mitochondrial glutamate accumulation and inactivation of the malate-aspartate shuttle in proliferating muscle stem cells. @debocklab @MorscherLab

https://t.co/bUrAf3vgMj

[Ben-David Lab @BenDavidLab]

Our Review on “Aneuploidy as a driver of human cancer” is out in Nature Genetics. Check it out! 🎉

The Ben-David lab wishes everyone Shana Tova — may the new year be much better than the ending one, bringing peace and stability to all! 🙏

https://t.co/OhfhqvpaMh

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

@GlattSebastian @AniRude95 @VetmeduniVienna Congratulations! Good start!!

[Giulio Superti-Furga @giuliosf]

We are excited to kick off our series of 4 manuscripts from the RESOLUTE consortium by sharing the metabolic mapping of the Solute Carrier Superfamily (https://t.co/OAn581qvIN)!

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

Amazing to contribute to the work of such team! Congratulations 🎉 very exciting work

[Sarah Cherkaoui @sarah_cherkaoui]

Very proud of our first paper @MorscherLab. It was great working hand-in-hand with the @debocklab to understand how metabolism controls muscle stem cell fate 🤝💪

[Eileen P. White, PhD @EileenWhitePhD]

Embracing Cancer Complexity: Hallmarks of Systemic Disease, now out in Cell!

https://t.co/DCTizDbjrG

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

Big thanks to Professor Johan Auwerx @Auwerx_Lab for the insightful talk on mitochondria & aging at @KispiZuerich. We enjoyed that you highlighted the power of mouse data to enable human health trajectories. Your expertise in metabolism and genetics has left us inspired 🧬

[Morscher Lab - #PediatricCancerMetabolism @MorscherLab]

Looking forward to joining you in Lyon on Friday!

[Cancer Research Center of Lyon @crcl]

🚨CRCL LECTURE🚨

We are honoured to receive Raphael J. Morscher from @MorscherLab @KispiZuerich @UZH_en !

📅March 22nd, 11:30 am

He will talk to us about " Targeting Metabolic Dependencies of Translation in Neuroblastoma" https://t.co/7kPhP5w5t7