Mostoslavsky Lab

The Mostoslavsky lab at Harvard & Mass General Cancer Center. We study chromatin, cancer, metabolism, DNA repair, PTMs et al. Tweets are from anyone in the lab!

[Mostoslavsky Lab @MostoslavskyLab]

Really excited to share our new study, where we identified ZNF280A, a novel regulator of homologous recombination during DNA repair, linked to the human 22q11.2 distal deletion syndrome. A special shout out to @ThomasLClarke for leading the project!
https://t.co/9aFJAOReNl

[Mostoslavsky Lab @MostoslavskyLab]

@jdelriopantoja @HarvardGSAS @MGHCancerCenter Excellent article Jose!! proud to have you in my lab!!

[José Del Río @jdelriopantoja]

Thanks @HarvardGSAS for featuring my story going beyond the dogmas of life. Cannot wait to formally share with the world all the cool science we’re doing at the @MostoslavskyLab @MGHCancerCenter.

https://t.co/by80AYnmR0

[Thomas Clarke @ThomasLClarke]

We’re happy to share our new study out today @NatureCellBio

We show that a chromatin factor, ZNF280A, is required for DNA double strand break repair, linking its absence to clinical features in 22q11.2 distal deletion syndrome.

@MostoslavskyLab

https://t.co/o4mEWhSLBT

[Ilaria G Gritti @IlariaG32]

Excited to share our new work on how DNAJB1-PRKACA drives cancer cell growth in Fibrolamellar Carcinoma.
@CD_AACR Thanks to all our collaborators and funding support. @FibroFoundation @AICF_nyc @DonaBertarelli @ForbeckForums @AlexLemonade

[Frontiers - Genetics @FrontGenetics]

New Research: Subcellular one carbon metabolism in cancer, aging and epigenetics https://t.co/eqyJX8UMtH #FrontiersIn #Epigenetics #Epigenomics

[Mostoslavsky Lab @MostoslavskyLab]

Really happy to share our new mini Review on One Carbon Metabolism and chromatin (fantastic job by @Tiz_bernasocchi. Out in @FrontGenetics https://t.co/F9arWQehcG

[Meng-Ju Wu @MJWu_TW]

New in @sciencemagazine! Our study reveals how mutant IDH1 inhibition activates tumor immunity by inducing dsDNA sensing. Read more: https://t.co/LrtJCwUOh5
#CancerResearch #Cholangiocarcinoma #IDH1 1/n

[Mostoslavsky Lab @MostoslavskyLab]

Our lab does a little bit of everything centered around chromatin biology and metabolism. No previous research experience needed, but preferred!

[Mostoslavsky Lab @MostoslavskyLab]

The Mostoslavsky Lab is looking for a highly motivated Research Technician interested in being part of our team for at least two years! Please share with your networks, and/or apply by sending an intro email with CV to: [email protected]

[Mostoslavsky Lab @MostoslavskyLab]

This will be a full-time research technician position, roles will include assisting with basic science techniques, from standard molecular biology to advanced biochemistry, genetics, and in vivo work.

[Mostoslavsky Lab @MostoslavskyLab]

@NCIYaminiDalal @NatureCellBio @NCIResearchCtr Ha ha! not sure I spoke about oncometabolites in the talk! :) We can chat about 2HG, probably the best oncometabolite example of how it affects chromatin by inhibiting all the a-KG dependent dyoxygenases.

[Mostoslavsky Lab @MostoslavskyLab]

Online now!! Really thrilled to share our latest work identifying a novel driver of metastasis, Gstt1, @NatureCellBio. A huge effort lead by Christina Ferrer and an incredible team of collaborators!!

https://t.co/hWssow2TxZ

[Mostoslavsky Lab @MostoslavskyLab]

@NCIYaminiDalal @NatureCellBio @NCIResearchCtr @WeyemiLab It was a pleasure to see you all there!!

[Mostoslavsky Lab @MostoslavskyLab]

@NCIYaminiDalal @NatureCellBio @NCIResearchCtr Thanks Yamini!!!!

[Mostoslavsky Lab @MostoslavskyLab]

@JAguirreGhiso @NatureCellBio Ehhh! Thanks Julio!! so happy it is out! You heard it long ago!

[Mostoslavsky Lab @MostoslavskyLab]

@Lloyd_Bod @NatureCellBio Thanks Lloyd!!

[Mostoslavsky Lab @MostoslavskyLab]

@sciqst @NatureCellBio Thanks Raffaele!!!

[Mostoslavsky Lab @MostoslavskyLab]

@FrezzaLab @NatureCellBio Thanks Christian!!

[Mostoslavsky Lab @MostoslavskyLab]

@FendtLab @NatureCellBio Thanks Sarah!!!

[Mostoslavsky Lab @MostoslavskyLab]

@BarakRotblat @NatureCellBio Thanks Barak!