Michael Nicholson

[Douglas Yao @DouglasYaoDY]

This vial contains a new drug called PAC-3310. It was designed by ChatGPT, and I synthesized it in a chemistry lab I built in my garage.

PAC-3310 is a new selective M4 muscarinic receptor agonist for treating schizophrenia - similar to the recent breakthrough drug Cobenfry, but improved. (1/7)

[Elon Musk @elonmusk]

https://t.co/yvJOwOS4xE

[Michael Nicholson @MrNicholson]

https://t.co/vGrzWa5V7U

[Michael Nicholson @MrNicholson]

@ZiaYusufUK That chirp

[Michael Nicholson @MrNicholson]

@PeptidePlugs Trying to place an order now - will it go out Tuesday?

[Robert Lassonde @RobLassonde]

🚨 Le mythe du racisme systémique s'effondre sous nos yeux avec la bombe nucléaire qui vient de paraître dans la revue NATURE.

David Reich, généticien de Harvard, avait lancé en 2018 une mise en garde dans le New York Times : il fallait sortir du déni car la génétique allait prouver l’existence de différences biologiques réelles entre les populations. Il affirmait que refuser de s’y préparer était une erreur qui nous disqualifierait face à la réalité scientifique à venir. Pour avoir brisé le tabou de la « page blanche », Reich a subi un désaveu massif et une condamnation publique.

Aujourd'hui, l’étude la plus massive de l’histoire (15 836 génomes anciens) vient de lui donner raison. La science confirme que l’évolution humaine ne s’est pas arrêtée : elle s’est ACCÉLÉRÉE MASSIVEMENT depuis 10 000 ans, provoquant une divergence biologique réelle dans l’intelligence et les comportements.

Nier ces faits pour maintenir l'illusion d'une intégration possible face à l'immigration de masse et continuer d'entretenir des mythes comme celui du racisme systémique est désormais un déni de science pur et simple. Une civilisation qui ignore la réalité biologique se condamne à l’effondrement. Le temps des faits est arrivé.

J’ai mis en commentaire quelques segments traduits de son avertissement de 2018 et le lien de l’étude pour ceux qui veulent comprendre l'ampleur du séisme.

[Nick shirley @nickshirleyy]

This daycare “Creative Minds Daycare” was SHUTDOWN and then reopened the next day under the name “Super Kids Daycare” they received $2,450,000 in 2025.

According to the DHS license website “Creative minds daycare” was closed on October 1, 2025 and the SAME day “Super kids” was opened. Once again NO kids to be seen and 3 BMW’s and a Range Rover parked outside. FRAUD.

Pirates Walz and Omar are silent while there is a 35% chance on @polymarket the fraudsters get deported back to Somalia.

Anyone else want to know where their taxes actually go?

[Michael Nicholson @MrNicholson]

@Bouazizalex You forgot about Samsara

[Michael Nicholson @MrNicholson]

•L-Leucine (Nutricost) – mTOR trigger for muscle protein synthesis. Works, but only matters if a meal is low in leucine (i.e., low-protein).
•HMB (Nutricost) – leucine metabolite; anti-catabolic, helpful during cuts/injury or very hard training. Redundant with leucine for most people—pick one.
•NAC 600 mg (Nutricost) – glutathione precursor; excellent for liver support and oxidative stress (on-brand for your PNPLA3/liver sensitivity).
•Taurine (Nutricost) – cell hydration, heart rhythm, calmer CNS; good pre-bed or pre-workout (1–2 g).
•Nitric Oxide “pump” – typically arginine/citrulline; fine pre-lift for blood flow, not a health pillar.
•Turmeric/Curcumin – anti-inflammatory; good for joints and liver inflammation. Absorbs better with fat/piperine.
•Quercetin + Zinc + Bromelain – immune/anti-inflammatory. Don’t double-dose zinc elsewhere.
•Berberine (looks like a quercetin/berberine/resveratrol blend) – insulin sensitivity, lipids. Potent; time with higher-carb meals.
•Boron (glycinate) – can drop SHBG a touch; 2–6 mg/day is the sweet spot.
•Digestive enzymes – use only if you have bloating/heavy meals; otherwise skip.
•Methylene Blue (USP) – mitochondrial redox toy. Edge-case performance/cognition; real interaction risks (see below).
•Pure Encapsulations (can’t read label) – looks like a core mineral (often magnesium).
•“Atomic Defense” & a generic “Multi” – proprietary/marketing-heavy immune blends; usually overlap with zinc/curcumin/quercetin.

Keep (core, evidence-heavy)
1.NAC 600 mg – 1–2×/day.
2.Taurine 1–2 g – PM or pre-workout.
3.Curcumin – 500–1,000 mg with a fatty meal (or a piperine/meriva form).
4.Magnesium glycinate (if that Pure bottle is Mg) – 200–400 mg at night.
5.Boron 3 mg/day – don’t exceed 6 mg.
6.(Add if not already): Creatine 5 g/day, Vitamin D3/K2, Omega-3 EPA/DHA. These are your highest-ROI staples.

Situational / cycle
•Berberine 500 mg with carb-heavy meals, 1–2×/day. Great if fasting insulin, A1c, or triglycerides creep up; otherwise cycle (8 weeks on, 4 off).
•Quercetin/Zinc/Bromelain – short runs for allergies, colds, or high-inflammation stretches. Watch total zinc (target 15–30 mg/day total; >40 mg long term tanks copper).
•Nitric Oxide – 30–60 min pre-training. Fun, not foundational.

Cut / consolidate (pill-fatigue + redundancy)
•Leucine or HMB – not both. If you’re eating 35–50 g protein/meal, you rarely need extra leucine; HMB is more useful during a cut or deload to preserve muscle.
•Digestive Enzymes – only if you notice a difference.
•Atomic Defense & the generic Multi – likely redundant with zinc/curcumin; drop unless you have a specific reason.

Big red flags / interactions (don’t gloss this)
•Methylene Blue: avoid if using SSRIs/SNRIs/MDMA/linezolid (serotonin syndrome risk). High doses behave like an MAOI (watch tyramine foods, certain meds). Also stains…everything. If you insist, micro-dose (e.g., 0.5–1 mg/kg) and cycle, but it’s optional fluff for your goals.
•Curcumin + Bromelain + Quercetin: all thin blood a bit—think twice before procedures or with anticoagulants.
•Berberine: don’t stack with metformin; can lower blood sugar—watch light-headedness during fasts.

Simple daily flow (no-nonsense)

AM (with food): NAC 600 mg, Boron 3 mg, Curcumin, (Fish oil), (D3/K2).
Pre-workout: Taurine 1–2 g, either HMB 1–3 g or Leucine 2–3 g, Pump product if you like.
With biggest carb meals: Berberine 500 mg (1–2×).
PM: Magnesium (Pure) 200–400 mg, Taurine 1 g if sleep/anxiety.
Immune/inflammation bursts: Short course of Quercetin/Zinc/Bromelain.

Bottom line

You’ve got a lot of winners, plus some shiny duplicates. Trim the fluff (multi/atomic, leucine or HMB, enzymes unless needed), keep the liver/testosterone stack tight (NAC, Mg, boron, D, omega-3), and use berberine/quercetin strategically. Methylene blue is optional—and spicy—so treat it like a tool, not a lifestyle.

[Michael Nicholson @MrNicholson]

•L-Leucine (Nutricost) – mTOR trigger for muscle protein synthesis. Works, but only matters if a meal is low in leucine (i.e., low-protein).
•HMB (Nutricost) – leucine metabolite; anti-catabolic, helpful during cuts/injury or very hard training. Redundant with leucine for most people—pick one.
•NAC 600 mg (Nutricost) – glutathione precursor; excellent for liver support and oxidative stress (on-brand for your PNPLA3/liver sensitivity).
•Taurine (Nutricost) – cell hydration, heart rhythm, calmer CNS; good pre-bed or pre-workout (1–2 g).
•Nitric Oxide “pump” – typically arginine/citrulline; fine pre-lift for blood flow, not a health pillar.
•Turmeric/Curcumin – anti-inflammatory; good for joints and liver inflammation. Absorbs better with fat/piperine.
•Quercetin + Zinc + Bromelain – immune/anti-inflammatory. Don’t double-dose zinc elsewhere.
•Berberine (looks like a quercetin/berberine/resveratrol blend) – insulin sensitivity, lipids. Potent; time with higher-carb meals.
•Boron (glycinate) – can drop SHBG a touch; 2–6 mg/day is the sweet spot.
•Digestive enzymes – use only if you have bloating/heavy meals; otherwise skip.
•Methylene Blue (USP) – mitochondrial redox toy. Edge-case performance/cognition; real interaction risks (see below).
•Pure Encapsulations (can’t read label) – looks like a core mineral (often magnesium).
•“Atomic Defense” & a generic “Multi” – proprietary/marketing-heavy immune blends; usually overlap with zinc/curcumin/quercetin.

Keep (core, evidence-heavy)
1.NAC 600 mg – 1–2×/day.
2.Taurine 1–2 g – PM or pre-workout.
3.Curcumin – 500–1,000 mg with a fatty meal (or a piperine/meriva form).
4.Magnesium glycinate (if that Pure bottle is Mg) – 200–400 mg at night.
5.Boron 3 mg/day – don’t exceed 6 mg.
6.(Add if not already): Creatine 5 g/day, Vitamin D3/K2, Omega-3 EPA/DHA. These are your highest-ROI staples.

Situational / cycle
•Berberine 500 mg with carb-heavy meals, 1–2×/day. Great if fasting insulin, A1c, or triglycerides creep up; otherwise cycle (8 weeks on, 4 off).
•Quercetin/Zinc/Bromelain – short runs for allergies, colds, or high-inflammation stretches. Watch total zinc (target 15–30 mg/day total; >40 mg long term tanks copper).
•Nitric Oxide – 30–60 min pre-training. Fun, not foundational.

Cut / consolidate (pill-fatigue + redundancy)
•Leucine or HMB – not both. If you’re eating 35–50 g protein/meal, you rarely need extra leucine; HMB is more useful during a cut or deload to preserve muscle.
•Digestive Enzymes – only if you notice a difference.
•Atomic Defense & the generic Multi – likely redundant with zinc/curcumin; drop unless you have a specific reason.

Big red flags / interactions (don’t gloss this)
•Methylene Blue: avoid if using SSRIs/SNRIs/MDMA/linezolid (serotonin syndrome risk). High doses behave like an MAOI (watch tyramine foods, certain meds). Also stains…everything. If you insist, micro-dose (e.g., 0.5–1 mg/kg) and cycle, but it’s optional fluff for your goals.
•Curcumin + Bromelain + Quercetin: all thin blood a bit—think twice before procedures or with anticoagulants.
•Berberine: don’t stack with metformin; can lower blood sugar—watch light-headedness during fasts.

Simple daily flow (no-nonsense)

AM (with food): NAC 600 mg, Boron 3 mg, Curcumin, (Fish oil), (D3/K2).
Pre-workout: Taurine 1–2 g, either HMB 1–3 g or Leucine 2–3 g, Pump product if you like.
With biggest carb meals: Berberine 500 mg (1–2×).
PM: Magnesium (Pure) 200–400 mg, Taurine 1 g if sleep/anxiety.
Immune/inflammation bursts: Short course of Quercetin/Zinc/Bromelain.

Bottom line

You’ve got a lot of winners, plus some shiny duplicates. Trim the fluff (multi/atomic, leucine or HMB, enzymes unless needed), keep the liver/testosterone stack tight (NAC, Mg, boron, D, omega-3), and use berberine/quercetin strategically. Methylene blue is optional—and spicy—so treat it like a tool, not a lifestyle.

[Michael Nicholson @MrNicholson]

@FaceTrades HODL

[Michael Nicholson @MrNicholson]

@SawyerMerritt Biden put the order in last December. Dumb.

[Michael Nicholson @MrNicholson]

@solanasteve_ @stoolpresidente Boo

[Michael Nicholson @MrNicholson]

@Cancelcloco Can confirm

[Elon Musk @elonmusk]

You are the media now

[Michael Nicholson @MrNicholson]

@StockSavvyShay Join!

[Michael Nicholson @MrNicholson]

No eggs, double beef

[Ben Smith @bensmithlive]

If you drink too much coffee, the effect is inverse.

It makes you tired, less focused, and burnt out due to excess cortisol, high brain stimulation, and agitation.

This stops today.

Here’s what coffee does to your brain (and how to drink it correctly): 🧵

[Elon Musk @elonmusk]

For every person you refer who is a swing state voter, you get $47! Easy money.

[George @BehizyTweets]

BREAKING: Peter Thiel says if the 2024 election is close, Kamala Harris will cheat to STEAL it. He's also joining people like Elon Musk and calling for strict Voter ID, in-person election-day voting, & heavy restrictions on mail-in voting

"They will cheat. They will fortify it. They will steal the ballots."

"At a minimum, you'd try to run elections the same way you do it in every other Western democracy. You have one day voting. You have practically no absentee ballots... It's not this two-month elongated process."

Video: @theallinpod

Everything Thiel said is FACTUAL. Democrats bend the rules to cheat, as we saw in broad daylight in the 2020 election. The good news is that we now know exactly how it all works.