Marc Soco, MD

Nephrologist 🇵🇭 • Internist • Flozinator • GN & Transplant • @uppghnephrology Alumni • @nephjc intern 2025-2026 @GlomCon Fellow 2023-2024 • @Neph_Sim 2021

[Marc Soco, MD @msocoMD]

Kidney injury occuring in liver failure is a historical scenario imbued w/in the parlance of medicine for centuries. In this article, I try to discuss HRS— its current concepts & challenges.

Thank you @Nephro_Sparks @DearbhlaKelly4 for helping me write this article!

[Renal Fellow Network @RenalFellowNtwk]

Hepatorenal Syndrome: Current Concepts and Challenges by @msocoMD https://t.co/7lAAebqPSP

[Nephrology Journal Club @NephJC]

#NephJC Consensus
From GEMRITUX, MENTOR, STARMEN, RI-CYCLO & now MAJESTY- the signal remains consistent:
✅ Anti-CD20 therapy works
✅ Remissions are durable
✅ Relapses are lower than CNIs
Check out anti-CD20 trials in pMN @CristinaDeReins👇
#NephJC #TenPostNephJC #NephTwitter

[Nephrology Journal Club @NephJC]

🚨New 🩳 by @CristinaDeReins
eGFRcr, eGFRcys, eGFRcr-cys, mGFR...
What does mGFR teach us about estimates?
#NephTwitter #MedTwitter #NephJC
https://t.co/NP2p9d11ga

[Nephrology Journal Club @NephJC]

#TenPostNephJC
#NephTwitter #NephJC
1/10
How often do we miss non-diabetic kidney disease (NDKD)?
🚩NDKD are 1) active urine sediment, 2) sudden worsening RFT, 3) absence of retinopathy 4) systemic symptoms like rash
@Tiff_Caza
https://t.co/0H9Rydx60J

[Marc Soco, MD @msocoMD]

@NephJC @DrBarbaTeba @AncaSt13 @dany_rcal @kiddo_kidney @AndrewDelaat @farahwehbe92 @rn_flex @assad_sm @ManoleaA @Nihal_Hamary @brian_rifkin @CristinaDeReins @dra_miliflores @DrAkshayaJ @kidney_boy @DrPallaviPrasad @drpriyajohn @DivyaveerSSNeph @Melgreux Congratulations, everyone! Excited to see all the great work you’ll accomplish

[Nephrology Journal Club @NephJC]

✨Exciting news #Nephtwitter

The new #NephJC editorial interns are here!

📢 Give them a follow and make them feel at home https://t.co/iqe5dTLD4A

@DrBarbaTeba @AncaSt13 @dany_rcal @kiddo_kidney @AndrewDelaat @farahwehbe92 @rn_flex @assad_sm
@ManoleaA @Nihal_Hamary

[Nephrology Journal Club @NephJC]

Hypertension control remains stubbornly low in underserved communities. IMPACTS‑BP asks whether a team‑based, multi‑component approach can meaningfully improve blood pressure control and adherence in low‑income patients

🎨#VisualAbstract by @DrAkshayaJ

https://t.co/liZjXaThwl

[Nephrology Journal Club @NephJC]

Tigris: 15k screened, 157 enrolled, and a result that depends on how much you trust the prior #NephJC
💡Signal? Yes
🤔Confidence? Not really

✍️#NephJCshort by @CristinaDeReins
🪓Reviwed by @hswapnil and @brian_rifkin

https://t.co/BNNnUiXdqD

[Nephrology Journal Club @NephJC]

1/10
#NephJC #TenPostNephJC.
#NephTwitter
In 2026 💊 FDA approved sparsentan for FSGS, an endothelin A/angiotensin II receptor inhibitor.
Next up in the pipeline…transient receptor potential cation channel 6 (TRPC6) inhibitor (BI 764198) 🚰
Article 👇
https://t.co/DxVeKVlF0x

[UP-PGH Nephrology @uppghnephrology]

Blessings abound! The Division received various awards during the recent convention:

1. One of the Most Outstanding Fellowship Training Institution in Adult Nephrology
2. 100% passing recent Board exams
3. One of the Best performing institution in test construction

#TatakPGH

[Nephrology Journal Club @NephJC]

Hydralazine, a 1950s drug still used at the edges of modern care
Cheap. Available.

Signal of benefit… shadowed by decades of immune toxicity signals

58 min to #TenPostNephJC #NephJC

https://t.co/IShXIbNyle

[GlomCon @GlomCon]

Managing glomerular disease in tropical regions require a specialized lens. Join #GlomConPH on April 22, 2026, for a high-impact workshop designed for physicians to master the nuances of tropical nephrology—from biopsy interpretation to navigating the latest KDIGO updates.

[Edgar V. Lerma 🇵🇭 @edgarvlermamd]

B Cell Modulation in IgA Nephropathy 🏆
#IgAN #Nephpearls #Nephmadness

Check out our review "IgA Nephropathy: An Overview of the Clinical Trials" by @ZohrehGh7 @haresh11 @NWiegley @Alexgr23 @rahaai @SaynaNorouzi @JEGAYTAN90 and the #Nephmadness write up by @LauraMarianiMD and @AleTomasiMD

👉 https://t.co/qYVbssRzLT
👉 @NephMadness https://t.co/fX7k5v0lbZ

[Nephrology Journal Club @NephJC]

0/10
Hey NephJC faithful, we are shaking it up.
Given the 📉 attendance at live chats we’re changing to a summary 🧵& ❓ to answer, at your convenience.
Still tag us #NephJC to get the discussion going!
PS If we hear enough comments, we might bring chats back!😉

[Nephrology Journal Club @NephJC]

Hey #NephTwitter #MedTwitter
📣If you were planning on coming to the #NephJC chat on hyponatremia 4/7/26 at 9 pm...relax, we're trying something new (and it will be here on Twitter too, not just BlueSky)!
https://t.co/TAbRWdgr7k

[Int Society of Nephrology @ISNkidneycare]

The IgAN Nephropathy curriculum provides a comprehensive review of the pathogenesis, treatment, and prediction of disease progression to help clinicians in their work.

Access the new curriculum, supported by Otsuka: https://t.co/KPQtAz86g0

[Cristina Popa 🦋 @NephroSeeker]

#ISNWCN second HIT1 trial

Semaglutide Improves Kidney Outcomes Regardless Of SGLT2i Use In People With Chronic Kidney Disease And Type 2 Diabetes: Post-hoc Analysis The Remodel Trial, by David Cherney

[Cristina Popa 🦋 @NephroSeeker]

#ISNWCN

First simultaneous publication comes from Hiddo Heerspink and ASSIST trial ✨

Phase II randomized crossover in IgAN on RASi+SGLT2i. Atrasentan 0.75 mg reduced 24-h UPCR vs placebo. ETA blockade adds antiproteinuric effect on top of optimized therapy

[Hamza Rage @hmzrage]

What’s new in AKI/AKD KDIGO updates compared to KDIGO 2012.
#ISNWCN

[Nephrology Journal Club @NephJC]

2/ @brian_rifkin 's recap highlighted our progress and future plans, but what stays with me is this: #nephjc never stops adapting. We keep learning, improving, and reaching for a better version of ourselves 🌟

[Nephrology Journal Club @NephJC]

1/ Today’s #nephjc graduation was pure joy. Seeing mentors and interns from around the world come together reminded me why this community matters.

✨Thank you for making it extraordinary

@hswapnil @Nephro_Sparks @salinesalut @FravelShellie @meyyappannephro @roxnonna23