MundlosLab

Bio - logy. Mutations, TADs, and gene regulation in development. All the good stuff. Tweets by @mphan_236 and lab members.

[MundlosLab @MundlosLab]

How to make a bat wing🦇? Check out the latest #evodevo preprint from the Mundlos Lab at @MPI_MolGen together with @RealFany and @Dariloops, led by our very own @M_Schindler_ and @ChrisFeregrino! https://t.co/ePMRiTFfTX
See the thread for more 👇

[Maria Stefanova @m_i_spiral]

(1) Chromatin/cancer paper alert! We've unraveled how genotoxic anticancer drug impacts the chromatin structure of human cells. Using Hi-C, ChIP-seq, and RNA-seq, we've explored the changes in chromatin architecture triggered by doxorubicin and ICRF193. https://t.co/0PpEQ6bbTb

[Juliane Glaser @GJuliane_]

Excited to share our story on how enhancers repositioning leads to disease-associated gene mis-expression during development out in @NatureComms 🧬🐁🤓 I couldn't be happier to have teamed up with @Giulia_Cova on this one! @MundlosLab
👇 https://t.co/rIKSW122XP

[Giulia Cova @Giulia_Cova]

And it’s officially out @NatureComms!!Couldn’t be happier 😃🥳!! A long way, but definitely worthy!!Thanks to my amazing partner-in-crime @GJuliane_ 🤗, all the authors, the reviewers, and to everyone that has been part of this journey 🤗 so grateful!! https://t.co/8wnmUd1kQY

[MPI for Molecular Genetics @MPI_MolGen]

🧬 Want to dissect the gene regulatory function of long non-coding RNAs using #genomicengineering #syntheticbiology? Join the lab of @StefanMundlos / @MundlosLab & our #IMPRS-BAC #gradschool! Apply today!
👉 https://t.co/ULKP0gVsYJ

[Nature Communications @NatureComms]

Researchers @MeloUira @StefanMundlos @MundlosLab @VingronLab characterize structural variations (SVs) in a cohort of individuals with complex genomic rearrangements and investigate their impact on gene expression and the 3D chromatin architecture.

https://t.co/Vdv2H5iUTV

[MundlosLab @MundlosLab]

Way to go! Congrats @Alessa_Ringel 🥳🥳🥳

[Genome Organisation Australia @GenomeOrgAus]

Last week we hosted the GOA Young TAD Award presentations. They were all amazing and the scoring was very tight! We are excited to announce the winner was @Alessa_Ringel 👏👏👏

[MPI for Molecular Genetics @MPI_MolGen]

🦔 Looking for a #PhD position & interested in investigating how the hedgehog got its spines? Join the lab of @StefanMundlos / @MundlosLab & our #IMPRS-BAC #gradschool! Apply today!
👉 https://t.co/x7KHU6RCd5

[Uirá Souto Melo @MeloUira]

We are happy to share the latest work from
@MundlosLab published on @NatureComms
We combined short- and long-read sequencing in samples with germline complex genomic rearrangements. https://t.co/zmDfharnCo

[Alessa Ringel @Alessa_Ringel]

Interested in gene regulation in disease? Stay tuned for @mrmikerobson1´s lab opening @BIMSB_MDC in April 2023.

[MundlosLab @MundlosLab]

The latest Mundlos lab evolutionary adventure in gene regulation continues.. Big congratulations to @Alessa_Ringel & @mrmikerobson1! Check out the tweetorial for the highlights ⬇️

[Stefan Mundlos @StefanMundlos]

Job alert Postdoc: you are a molecular biologist and interested in gene regulation? Study how lncRNAs work in regulating genes in development. Use cutting edge technologies including synthetic genomics and large-scale genomic engineering. Contact me. https://t.co/fGLUtvd29p

[MundlosLab @MundlosLab]

Congrats everyone, especially our very own @KraftKaterina & @Andreas_Magg 🍾🥂 A must-read for all 3D- & Polycomb-enthusiasts!

[Katerina Kraft @KraftKaterina]

Thank you @KatieEYost @HowardYChang @SedonaMurphy @Andreas_Magg @YichengLong @ABoettiger @StefanMundlos Tom Cech
Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation | Proceedings of the National Academy of Sciences https://t.co/THKp0vCpvg

[Stefan Mundlos @StefanMundlos]

Thanks so much to everybody for support in this #ERCAdG endeavor! It has been a tough competition. I see it as a special honor that my project was viewed as "ostentatiously overambitious" by a reviewer. Peer reviews are so much fun! 😂

[MPI for Molecular Genetics @MPI_MolGen]

🍾 Congratulations! 🎉 For a a research project on the genomics of evolution, or “how bats learned to fly”, our researcher @StefanMundlos / @MundlosLab has been awarded a prestigious @ERC_Research Advanced Grant #ERCAdG https://t.co/yuRhWOG9hV

[Nationale Akademie der Wissenschaften Leopoldina @Leopoldina]

Anlässlich ihrer Jahresversammlung zeichnet die Leopoldina ForscherInnen für ihre hervorragenden wissenschaftlichen Leistungen aus. Mehr: https://t.co/uspvIGSWs7
@CoBaStiftung

[Jakob Hertzberg @j_hertzberg]

I am excited to announce the publication of TADA, a tool to prioritize pathogenic CNVs @GenomeBiology! TADA annotates CNVs with respect to the affected regulatory environment and computes a pathogenicity score indicating their functional impact.
https://t.co/pjfiev8d5r

[MundlosLab @MundlosLab]

@Giulia_Cova is now a post doc in NYC @nyulangone. Feel free to reach out to her if you have any questions!

[MundlosLab @MundlosLab]

Check out our new @biorxivpreprint! A bona fide Mundlos Lab's study looking at structural variations leading to gene dysregulation @ the Lbx1/Fgf8 locus. An impressive effort lead by @Giulia_Cova & brought to the finish line by @GJuliane_ #preprint #3DGenome

[Giulia Cova @Giulia_Cova]

Extremely happy to share the preprint of my work from my time in the @MundlosLab! A novel conceptual framework where combination of gene misexpression and dosage occurs upon structural variations that involve the Lbx1/Fgf8 locus and its 3D organization.
https://t.co/syMivnCczm

[MPI for Molecular Genetics @MPI_MolGen]

🦇 Join the lab of @StefanMundlos / @MundlosLab / @der_bri to find out how bats learned to fly! To uncover the complex changes in its genome, apply as a #PhD student & join our #IMPRS-BAC research school!

👉 https://t.co/CfXXtFSOJL