Michael Orlov, MD, PhD

[Michael Orlov, MD, PhD @MvorlovOrlov]

@jettymd @Hisdoc1 @ThatGuyRyu we forgot to mention that this was Abbott lead. Would have been impossible w/o stylet

[v jetty @jettymd]

Microdislodgement of LBAP with sheath splitting? We lost pacing from the ring and were able to reposition using a few turns of the lead without a sheath to regain capture from the ring and selective LB capture. @MvorlovOrlov @Hisdoc1 #EPeeps #CardioTwitter

[Michael Orlov, MD, PhD @MvorlovOrlov]

@narrowQRS Excellent!

[Peng-Sheng Chen, MD @DrPengShengChen]

Michael V. Orlov et al had the following paper accepted for publication by Heart Rhythm: "Is Competitive Atrial Pacing a Possible Trigger for Atrial Fibrillation? Observations from the RATE Registry"

[Michael Orlov, MD, PhD @MvorlovOrlov]

Some recent thoughts on QT prolongation with hydroxychloroquine

[Ahad Jahangir @jahangir_ahad]

https://t.co/AL87rdw8vJ @MvorlovOrlov

[Eagle Point Medical @eaglepointmed]

Our novel concept for pacing:

A single conduit, multi pronged electrode allowing sequential pacing of atrium and His bundle from one location!

https://t.co/JEqGx7jnbC

Thankyou @MvorlovOrlov and
@Hisdoc1 for the hard work!

@HRSonline #HRS2020Science #Dontdisthehis

[Adam Brufsky @breastoncdoc]

Mike Lotze (a dendritic cell maven) and I published a followup on this in J Med Virol yesterday. We were waiting for the paywall to lift (why was it paywalled, not sure) to get this out there. Not sure if the paywall lifted, but it should soon.

https://t.co/ptrHZEzlLI

[Adam Brufsky @breastoncdoc]

The bottom line is that it looks like SARS-CoV-2 infects the dendritic cell using both ACE2 and DC-SIGN. It infects the type II pneumocyte and the endothelial cell using ACE2 and L-SIGN/CD209.

Glycosylation of the S protein spike affect binding and internalization by DC/L-SIGN.

[Adam Brufsky @breastoncdoc]

More glycosylation, more binding and internalization. Less glycosylation, less binding and internalization.

Just like SARS-CoV.

Should affect virulence, both pathogenesis and transmission.

[Michael Orlov, MD, PhD @MvorlovOrlov]

@drpmoskal @Hisdoc1 @ZacharyWhinnett @narrowQRS @jahangir_ahad @KennethEllenbo1 @nycrhythmdoc Nice paper

[Michael Orlov, MD, PhD @MvorlovOrlov]

Very interesting to observe how the 3830 lead deploys differently in the muscular septum vs. AV septum in porcine heart. Helpful for implanters. Comments? @Hisdoc1 #EPeeps #dontdisthehis @ZacharyWhinnett @narrowQRS @jahangir_ahad @KennethEllenbo1 @nycrhythmdoc

[Michael Orlov, MD, PhD @MvorlovOrlov]

@narrowQRS In the best traditions of moguls of Cardiology!

[Michael Orlov, MD, PhD @MvorlovOrlov]

@drjohnm Price of healthcare has skyrocketed due to expense of compliance and auditing. The complexity of medical care provided by trained physicians has to be sacrificed for less expensive services. Studies will be put forward justifying the means and outcomes data that is inconclusive

[Michael Orlov, MD, PhD @MvorlovOrlov]

@DCR_Dr @PrashSanders @Canberra_Rhythm @drrpathak @EPeeps_Bot @hisbundlepacing @Hisdoc1 @UlhasDr @BIOTRONIK @BIOTRONIK_News What was the capture threshold? R wave? How did the system handle?

[Michael Orlov, MD, PhD @MvorlovOrlov]

This may be a great tool in clinic

[JMC @narrowQRS]

👍A.fib free patient education videos x2 are proving to be a hit!
They streamline office visits because the patient starts out more informed.
Feel free to send these 2 links to your AF pts before a visit!
Let me know if they help!

https://t.co/WqB8aqLWlo
https://t.co/R3UrdsL7cQ

[Michael Orlov, MD, PhD @MvorlovOrlov]

@DrRoderickTung But combined w CRT per Dr. Herweg - can

[Michael Orlov, MD, PhD @MvorlovOrlov]

New exciting concept for pacing! Single conduit, multi pronged electrode allowing sequential pacing of atrium and His bundle from one location. Thankyou Dr Vijayaraman for participating in animal experiments. @hisdoc1 #pps2019 #dontdisthehis https://t.co/PTZXUomQaR

[Michael Orlov, MD, PhD @MvorlovOrlov]

@jeffrey_vinocur @Hisdoc1 @gopi_gdanda1 @MdHuang Was this a His bundle pacer? Looks like RBBB and LAFB were corrected w pacing

[Michael Orlov, MD, PhD @MvorlovOrlov]

@KanwarAulakh You r probably correct, that may explain deep S in V5,6 - LAFB appearance. Famous LB picture that we should have in mind when placing those leads

[Michael Orlov, MD, PhD @MvorlovOrlov]

My first successful LB pacing case. Patient w CHB and EF 47%. Deployed LB lead significantly lower than than I thought when compared to His capture spot. Capture LB at [email protected] ms. QRS 95 ms

[Michael Orlov, MD, PhD @MvorlovOrlov]

@J_CostelloDO Standard C315