Myopathy_Clínic

Unidad de patología muscular del Hospital Clínic de Barcelona

[Iago Pinal-Fernandez @DrIagoPinal]

Excited to share our latest @ARD_BMJ study! We reveal the mechanism by which autoantibodies enter cells, disrupt their target autoantigens, and drive tissue injury and inflammation in myositis and other autoimmune diseases. 🧬

https://t.co/nbX62hRSb6

[Iago Pinal-Fernandez @DrIagoPinal]

🧬🚨New in @medrxivpreprint: Spatial transcriptomics reveals mechanism of autoimmunity driven by internalized autoantibodies: antibody secreting cells induce antibody internalization, disrupt autoantigen function, and drive muscle damage and inflammation

https://t.co/3ewfZxgd7k

[José C. Milisenda @MilisendaC]

https://t.co/AwuMqKKbFK

[IDIBAPS @idibaps]

@hospitalclinic @CIBERER @mitometlab @NIH @SaludISCIII @GortLaura 🆕 El #CLÍNIC-#IDIBAPS participa en un estudi on s’ha descobert un nou tipus de Síndrome de Depleció-Deleció d’ADN Mitocondrial

L’estudi descriu com les mutacions en el gen GUK1 causen aquesta nova forma de MDDS

👉https://t.co/9JpdrhwQvA

[MitoMetLab @mitometlab]

🧬We've recently participated in this work in which GUK1 is identified as the cause of syndromes related to mitochondrial DNA maintainance.

Guanylate Kinase 1 Deficiency: A Novel and Potentially Treatable Mitochondrial DNA Depletion/Deletions Disease
https://t.co/ZDdxH3Igt3

[José C. Milisenda @MilisendaC]

Hamstrings on focus: Are 72 hours sufficient for recovery after a football (soccer) match? A multidisciplinary approach based on hamstring injury risk factors and histology

https://t.co/6xz5ARV8c5

[José C. Milisenda @MilisendaC]

Systemic sclerosis and inflammatory myopathy after treatment with durvalumab in a patient with rectal neoplasm

https://t.co/uBq203Q1w8

[Hospital Clínic @hospitalclinic]

Investigadors del #CLÍNIC-@idibaps han participat en un estudi sobre els mecanismes implicats en la miopatia inflamatòria idiopàtica.

🔬 Revela com els anticossos poden entrar a les cèl·lules musculars i interferir amb les seves funcions normals.

 👉 https://t.co/zT6yKmzgdg

[IDIBAPS @idibaps]

@Myopathy10 @MilisendaC @mitometlab @hospitalclinic @CIBERER 🆕Descubren un mecanismo clave en las Miopatías Inflamatorias Idiopáticas

Investigadores del #CLÍNIC-#IDIBAPS han participado en un estudio que revela cómo los anticuerpos pueden entrar en las células musculares e interferir con las funciones normales

👉https://t.co/7TrqomZ739

[Iago Pinal-Fernandez @DrIagoPinal]

Pathological autoantibody internalisation in myositis https://t.co/4cxe2wUNm9

[José C. Milisenda @MilisendaC]

https://t.co/0QcvuM6Sgb

[Sociedad Española de Medicina Interna @Sociedad_SEMI]

🩺🏥Desde @Sociedad_SEMI lamentamos profundamente la pérdida del profesor y Dr. J. M. Grau, un referente en nuestra especialidad y destacado internista que ejerció en el @hospitalclinic. DEP.
https://t.co/B4F3BRbtwT #MedicinaInterna #condolencias #DEP

[José C. Milisenda @MilisendaC]

https://t.co/L0F9vSnUUI

[Iago Pinal-Fernandez @DrIagoPinal]

In myositis, autoantibodies are internalized into muscle fibers, disrupt the biological function of their autoantigen, and mediate the pathophysiology of the disease.

https://t.co/JtTExOvuME

[Myopathy_Clínic @Myopathy10]

Neurological adverse events related to immune-checkpoint inhibitors in Spain: a retrospective cohort study

https://t.co/eLdDCV0WgV

[José C. Milisenda @MilisendaC]

The international team!!! Important things coming. Just a little sample at this ACR 2023.

[Alfredo Guillén-del-Castillo @_AlfredoGuillen]

Enhorabuena a Andrea @UMAS_Mutua y el resto del grupo @MilisendaC @MAS_Clinic por el excelente trabajo ! 👏🥳

[Myopathy_Clínic @Myopathy10]

Treatment of Myositis Associated With Immune Checkpoint Inhibitors

https://t.co/HSFwp6nL5L

[Myopathy_Clínic @Myopathy10]

Homenaje al Dr. Grau
1983-2022

[José C. Milisenda @MilisendaC]

Amyloid polyneuropathy in a patient with Waldenströn macroglobulinemia

https://t.co/FuBt8RRrHS