Postdoc @ColumbiaUniversity at the Center for Translational & Computational Neuroimmunology | systems biology, cell signaling, plasticity 🏳️🌈🇲🇴 (she/her)
🚀Our latest work uncovering the cell-cell signals driving an #astrocyte state linked to cognitive decline in #Alzheimer’s🧠Shoutout to my amazing collab. - Aiqun Li,Bin Zhang,Roland Friedel,@YoungPearseLab,David Bennett
https://t.co/DkngFA0dMc
#SingleCell#SpatialTranscriptomics
Check out our latest work: SHERLOCK🕵️ combines #RepresentationLearning of single-cell #perturbations with #CausalInference of their downstream transcriptional effects, supported by theoretical identifiability results 👇 https://t.co/O5sotQvXYm
New TYP lab paper out today in @PNASNews from former PhD student Zach Augur and postdoc @FogoGarrett all about how astrocytic BAG3 coordinates Alzheimer's proteostasis proteins! Read all about it here: https://t.co/BWh6nkkyc4
Happy to share our lab's paper published in @CellReports: led by talented PhD student, Yonatan Degefu at @UVABME, showing how cell state #plasticity (in #melanoma) is shaped by co-regulated, competitive, configurable interactions within the AP-1 network: https://t.co/zkJvdIockw
Excited to share our new work from Rosalind Xu, where we used MERFISH to build a single-cell spatial transcriptomic atlas of the mouse gut—and to explore host-microbiome interactions in situ! https://t.co/PFcrFPx8ih 1/
Excited to share our lab's latest work by @CaraAbecunas in collaboration with Audrey Kidd, Ying Jiang and @hui_zong: A systems approach to identify synthetically lethal associations between tumor metabolic state, driver mutations, and actionable targets. @UVABME@UVACancerCenter
Thrilled to share I’ve been awarded an @alzassociation AARF for my research into the drivers of glial cellular communities in aging brains. Grateful to Phil De Jager, Vilas Menon,@YoungPearseLab, Andrew Sproul, @MFallahiSichani for their support and mentorship!#ENDALZ#ALZFunded
New TYP lab preprint alert! Our previous PhD student Hyo Lee (& amazing collaborators) profile iPSC-derived astrocytes from 44 ROSMAP individuals and compare to brain data from the same people! You can find all the cool findings here:
https://t.co/HK4XMrdjQW
Excited to share our new
@biorxivpreprint in which we demonstrate the formation and maintenance of cellular memories in melanoma during acquisition of therapy resistance - dependent on the transcription factor AP-1 https://t.co/YBa6Gtbq5i (1/9)