Disparity in the regulation and prevention of water versus sodium imbalance in heat-stress nephropathy: a phylogenetic perspective
https://t.co/havCsE6Zsb
New Editorial from #NephFaculty Dr Sinclair and Dr Edmonston in KI Reports
It’s About Time: Potassium Risk With Combination Guideline-Directed Medical Therapy
https://t.co/SWDVTUSs0U
Kappa light chain crystalline podocytopathy and proximal tubulopathy from 43 yo woman with 3 y history of microscopic hematuria and mild proteinuria. All pictures from https://t.co/ZzxsH4sfy0
The photomicrograph shows a distended tubule with an intratubular crystalline cast with agryophilia. While crystalline casts can be seen from calcium phosphate, calcium oxalate and others, the presence of agryophilia on sliver stain is characteristic for 2,8-Dihydroxyadenuria (DHA) crystals. 2,8-DHA is a rare, autosomal recessive trait caused by a genetic deficiency in adenine phosphoribosyltransferase (APRT). Accurate diagnosis is critical (especially in those with limited chronicity) as treatment exists that can ameliorate renal damage in some patients. And, in patients with undiagnosed disease who undergo transplant, the disease will reoccur unless pharmacologic intervention is initiated. Of note, agryophilic, birefringent crystals can also be seen in patients exposed to triamterene which should always be excluded before a diagnosis of 2,8-DHA is rendered.
#renalpath #kidneypath #pathology #renal #pathtwitter
Pre-transplant and persistent post-transplant hyperparathyroidism and kidney transplant outcomes: a systematic review and meta-analysis
https://t.co/HeDBvj4gKw
Pregnancy associated AKI continues to challenge physicians with diagnostic uncertainty; could cell-cycle arrest biomarkers help? Read the full article in #ASNKidneyNews: https://t.co/W5IptSWyiJ
Original Article: Sodium Bicarbonate for Critically Ill Adults with Metabolic Acidosis and Shock (SODa-BIC trial) https://t.co/uTtuin6rig
#CCR26 | @CritCareReviews
Now online in @NDTsocial
Peptide Epitope Mapping of Anti-nephrin antibodies in FSGS
🧐Patient plasma binding was restricted to a small subset of nephrin peptides
▶️ https://t.co/piXORfppoU
Association between nephrolithiasis and kidney disease progression in patients with autosomal dominant polycystic kidney disease: a prospective cohort study
https://t.co/UMHrF5ndU8
Podocyte-Targeted Therapy in Focal Segmental Glomerulosclerosis: Insights from a Phase 2 Trial of TRPC6 Inhibition
https://t.co/h9N2etEQkl
@lfsanchez0104@GeorgeVasquezR2@kirkcampbell
Is the use of nondialyzable vs dialyzable beta-blockers associated with different cardiovascular outcomes among patients initiating hemodialysis? Find out in #ASNJASN https://t.co/WMlBvtZVTi
A small phase 2 trial suggests rilparencel may slow CKD progression in diabetes by ~78%. Early but promising step toward regenerative kidney treatments; phase 3 underway. https://t.co/7RhufRKdXW
Risks of Hypocalcemia and Other Bone Mineral Disorders for Denosumab Versus Zoledronate Across the Spectrum of Kidney Function: A Target Trial Emulation
https://t.co/0giZT4Hklj