Natthasith Trakarnsrisunun

Nephrology Fellow

[CKJ @CKJsocial]

Disparity in the regulation and prevention of water versus sodium imbalance in heat-stress nephropathy: a phylogenetic perspective

https://t.co/havCsE6Zsb

[Duke Kidney @DukeKidney]

New Editorial from #NephFaculty Dr Sinclair and Dr Edmonston in KI Reports

It’s About Time: Potassium Risk With Combination Guideline-Directed Medical Therapy

https://t.co/SWDVTUSs0U

[Boonyarit Cheunsuchon, MD @roboonya]

Kappa light chain crystalline podocytopathy and proximal tubulopathy from 43 yo woman with 3 y history of microscopic hematuria and mild proteinuria. All pictures from https://t.co/ZzxsH4sfy0

[Arkana Laboratories @arkanalabs]

The photomicrograph shows a distended tubule with an intratubular crystalline cast with agryophilia. While crystalline casts can be seen from calcium phosphate, calcium oxalate and others, the presence of agryophilia on sliver stain is characteristic for 2,8-Dihydroxyadenuria (DHA) crystals. 2,8-DHA is a rare, autosomal recessive trait caused by a genetic deficiency in adenine phosphoribosyltransferase (APRT). Accurate diagnosis is critical (especially in those with limited chronicity) as treatment exists that can ameliorate renal damage in some patients. And, in patients with undiagnosed disease who undergo transplant, the disease will reoccur unless pharmacologic intervention is initiated. Of note, agryophilic, birefringent crystals can also be seen in patients exposed to triamterene which should always be excluded before a diagnosis of 2,8-DHA is rendered.

#renalpath #kidneypath #pathology #renal #pathtwitter

[CKJ @CKJsocial]

Pre-transplant and persistent post-transplant hyperparathyroidism and kidney transplant outcomes: a systematic review and meta-analysis

https://t.co/HeDBvj4gKw

[ASN Publications @asnpublications]

Pregnancy associated AKI continues to challenge physicians with diagnostic uncertainty; could cell-cycle arrest biomarkers help? Read the full article in #ASNKidneyNews: https://t.co/W5IptSWyiJ

[NEJM @NEJM]

Original Article: Sodium Bicarbonate for Critically Ill Adults with Metabolic Acidosis and Shock (SODa-BIC trial) https://t.co/uTtuin6rig

#CCR26 | @CritCareReviews

[Hans-Joachim Anders @hjanders_hans]

Now online in @NDTsocial

Peptide Epitope Mapping of Anti-nephrin antibodies in FSGS

🧐Patient plasma binding was restricted to a small subset of nephrin peptides

▶️ https://t.co/piXORfppoU

[CKJ @CKJsocial]

Association between nephrolithiasis and kidney disease progression in patients with autosomal dominant polycystic kidney disease: a prospective cohort study

https://t.co/UMHrF5ndU8

[AJKD @AJKDonline]

Podocyte-Targeted Therapy in Focal Segmental Glomerulosclerosis: Insights from a Phase 2 Trial of TRPC6 Inhibition

https://t.co/h9N2etEQkl

@lfsanchez0104 @GeorgeVasquezR2 @kirkcampbell

[ASN Publications @asnpublications]

Is the use of nondialyzable vs dialyzable beta-blockers associated with different cardiovascular outcomes among patients initiating hemodialysis? Find out in #ASNJASN https://t.co/WMlBvtZVTi

[Abdelhamed Hamdy @Abdelhamed6261]

Anti Nephrin may be not for practice

[ASN Publications @asnpublications]

A small phase 2 trial suggests rilparencel may slow CKD progression in diabetes by ~78%. Early but promising step toward regenerative kidney treatments; phase 3 underway. https://t.co/7RhufRKdXW

[AJKD @AJKDonline]

Risks of Hypocalcemia and Other Bone Mineral Disorders for Denosumab Versus Zoledronate Across the Spectrum of Kidney Function: A Target Trial Emulation

https://t.co/0giZT4Hklj

[CKJ @CKJsocial]

Cholecalciferol and muscle strength in hemodialysis patients: results from the randomized VITADIAL trial

https://t.co/gY9tqqYc7a

[Abdelhamed Hamdy @Abdelhamed6261]

PGNMID

[Abdelhamed Hamdy @Abdelhamed6261]

Genetics 🧬 in kidney disease

[Abdelhamed Hamdy @Abdelhamed6261]

CKRT with Alkalosis

[Gopambuj Singh Rathod @IamGopambuj]

Membranous nephropathy is no longer just “primary vs secondary” disease — it is now an ANTIGEN-SPECIFIC podocytopathy.

🔬 Newer antigens are redefining diagnosis & prognosis:
▪️ NELL1 → malignancy/drug-associated MN
▪️ EXT1/EXT2 & NCAM1 → lupus/autoimmune MN
▪️ SEMA3B → pediatric MN
▪️ FAT1 → post-HSCT MN
▪️ CNTN1 → neuropathy-associated MN
▪️ PCDH7 → indolent MN phenotype

⚡ Emerging concept: Dual-antigen MN
(NELL1+PLA2R, NCAM1+EXT1/2 etc.) suggesting complex autoimmune evolution.

🧪 Mass spectrometry-based antigen mapping is becoming the future gold standard for PLA2R-negative MN.
#GSR #BuddingNephros #MembranousNephropathy #RenalPathology #NephTwitter #MedTwitter

[Grace Choung, MD 박영이 @grace_choung]

#ULTRAPATH26
Dr. Brealey @JohnBrealey - Karyomegalic Tubulointerstitial Nephropathy
#EM #ultrastructuralpathology