Nazish Sayed MD, MS, PhD

Associate Professor @StanfordCVI @stanfordvasc @StanfordSurgery interested in #Endothelial & #Vascular Biology, #CardioOncology, and Reg Med. #Cancer survivor

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

Excited 2 share our new paper @ScienceTM. V show how a cancer drug disrupts blood-vessel #mechanosensing via #PIEZO1, driving #hypertension & #cardiac dysfunction & how restoring #endothelial function protects🫀 @Joseph_C_Wu @maryhawn @StanfordSurgery
https://t.co/u50jq7dgET

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

@NickLeeper78 @StanfordVasc Thank you Nick for all the support.

[Science Translational Medicine @ScienceTM]

The ion channel protein #PIEZO1 protects against cardiac injury during #cancer treatment with tyrosine kinase inhibitor #TKI #sunitinib, according to a new study in mice and patient-derived #endothelial cells. @StanfordMed https://t.co/m2J9qxBW5V

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

Excited 2 start 2026 with a review in @VMJ_SVM on #iPSC based #NAMs (#Vascular #Organoids, #multiomics) for rare vascular disease. Thx 2 Lu Liu David Wu PhilTsao @NickLeeper78 for Collab & @Joseph_C_Wu @maryhawn @StanfordSurgery 4 support. #RareDisease

https://t.co/AlKQUUh1Hd.

[Stem Cell Podcast @stemcellpodcast]

#Sunitinib is an effective cancer treatment, but exposure can result in #hypertension & #HeartFailure. Dr. @Nazish_Sayed's lab at @StanfordCVI restored #PIEZO1 expression to reverse sunitinib-induced #endothelial dysfunction.

🔖 https://t.co/0NgxJhSuDc
🗨️ https://t.co/iR7uO7d0B5

[Endothelial Cell News @endothelialnews]

In this new @ScienceTM study from the lab of Dr. @Nazish_Sayed at @StanfordCVI, researchers identify a role for PIEZO1, a mechanically activated ion channel, in tyrosine kinase inhibitor-induced #cardiotoxicity and present a potential avenue for prevention.

🔗 https://t.co/aSsB8cLKDd

[Stanford CVI @StanfordCVI]

When life-saving cancer drugs put the heart at risk
New research from @stanfordcvi reveals how TKI sunitinib disrupts blood vessels’ ability to sense blood flow, driving hypertension & heart damage.
Read more: https://t.co/EgxxkBfegM
@Nazish_Sayed, @StanfordSurgery, @ScienceTM

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

Thx to collaborators @amitmanhas07, Yu Liu, Noishiki, David Wu, Tripathi, Sarah Mirza, @iDilipThomas, Lu Liu, @avirupguha , Nguyen, Chen, Chitalia, Cheng, @dannysayed, @melindatelli, Karim Sallam, @Joseph_C_Wu
Thx @Amanda_J_Chase for this amazing write up.
https://t.co/gYrwC1knof

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

Excited 2 share our new paper @ScienceTM. V show how a cancer drug disrupts blood-vessel #mechanosensing via #PIEZO1, driving #hypertension & #cardiac dysfunction & how restoring #endothelial function protects🫀 @Joseph_C_Wu @maryhawn @StanfordSurgery
https://t.co/u50jq7dgET

[Stanford Vascular @StanfordVasc]

Baszucki Research Day 2025 ✨

We welcomed Dr. Ulf Hedin from Karolinska Institute as our Baszucki Visiting Professor. From dinner with faculty & residents to a keynote on precision medicine, Biobank tour, & Grand Rounds on biobanking—what a week of innovation & collaboration! 🔬

[Stanford Vascular @StanfordVasc]

Stanford researchers led by Drs. @NickLeeper78, @Nazish_Sayed, & @EriFukayaMD have developed an induced pluripotent stem cell (iPSC) line from a patient with varicose veins — paving the way for in vitro modeling of venous disease.

🔗: https://t.co/z150Boxrpl

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

Sharing our recent review @JMCCardiology
We discuss how #LongCOVID drives cardiovascular complications & highlight the promise of #NAMs, #iPSC, #organoids & #AI in advancing diagnostics & therapies. @iDilipThomas @Joseph_C_Wu @StanfordCVI @StanfordSurgery
https://t.co/6bD0HAKgjd

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

Came home to this beautiful surprise — truly touched by the kindness and support 🌸

Grateful to @StanfordVasc @StanfordSurgery @StanfordCVI @maryhawn @Joseph_C_Wu @RLDalmanMD for supporting this promotion!

Thx #Sayed Lab and friends @iDilipThomas @amitmanhas07 @chun_liu_86

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

@StanfordDeptMed @StanfordMed Congratulations Karim. So well deserved.

[Stanford Vascular @StanfordVasc]

🧬 iPSCs shed light on vascular Ehlers-Danlos syndrome—Dr. Lu Liu brings new insights from endothelial cell modeling. @Nazish_Sayed #Holman25

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

Thank you @CircAHA for highlighting our recent paper on LMNA-related Dilated Cardiomyopathy. Need more studies that repurpose already FDA approved drugs for existing cardiac diseases @StanfordCVI @StanfordSurgery @SeanM_Wu @Joseph_C_Wu @josephahill @heshamasadek @American_Heart

[Circulation @CircAHA]

Olmesartan may provide targeted, mutation-specific therapy for HF patients with an LMNA mutation @SeanM_Wu @Nazish_Sayed @SJovinge https://t.co/ipGtZSecMb

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

"Teaching old drugs new tricks!
Folks, our paper in @CircAHA explores repurposing olmesartan for LMNA-DCM using #iPSC-derived CMs and leveraging NIH funded @LINCSProgram data. @Joseph_C_Wu @SeanM_Wu @chun_liu_86 @maryhawn
https://t.co/lMwNzzON4Z

[Stanford CVI @StanfordCVI]

Congrats 🥂 to @StanfordCVI researcher @Nazish_Sayed on a @CircAHA paper identify a #DrugRepurposing candidate for treating heart disease, found by analyzing gene expression in diseased hearts
https://t.co/PQX0lUQ7bw
@StanfordMed @StanfordSurgery @StanfordVasc @StanfordDeptMed

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

@ArunSharmaPhD @CSRegenMedicine Awesome. Congrats Arun.

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

Great lab and great mentor.

[Liya Yin, MD, PhD @UAZ Medicine-Phoenix @yly99129]

Yin lab is recruiting for positions at the University of Arizona, College of Medicine, Phoenix. If you’re interested in coronary microcirculation in diabetes and Heart Failure, please join us!
Researcher/Scientist - https://t.co/pewUZmX1BK
Postdoc - https://t.co/hNvQZMGAFf

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

@HaoYin20 @NatureCVR @iDilipThomas @StanfordCVI @StanfordSurgery @maryhawn @StanfordVasc Here is the link for the paper. Please forward as needed. https://t.co/2bRqtUq5iY

[Nazish Sayed MD, MS, PhD @Nazish_Sayed]

Our paper on endothelial - cardiomyocyte crosstalk in #LongCovid is now online @NatureCVR. It highlighting the importance of early vascular health monitoring in patients with #LongCovid. @iDilipThomas @StanfordCVI @StanfordSurgery @maryhawn @StanfordVasc
https://t.co/qMgobp46hA

[American College of Surgeons @AmCollSurgeons]

🏆 Congratulations to Dr. Mary Hawn (@maryhawn) of @StanfordSurgery, who will receive the 2024 Wangensteen Scientific Forum Award at #ACSCC24 this weekend!

Learn more about Dr. Hawn's academic leadership and prolific scientific research. https://t.co/FwBa15ZDkz