Neal S Parikh MD

Neurology, vascular neurology, epidemiology. Alnylam employee; views and opinion are my own.

[JAMA Neurology @JAMANeuro]

Is left atrial appendage occlusion a valuable treatment option for patients with atrial fibrillation and #breakthroughstroke despite anticoagulation therapy? @davidseiffge @boersma_lucas https://t.co/k9jxdatuDM

[Neal S Parikh MD @NealSParikhMD]

Tough topic
good to have some data

[Stephan A Mayer @stephanamayer]

What to do with an ICH patient who bled while on AC for a mechanical heart valve? When and how to restart AC?

This is a cool study showing that the risk of bleeding complications far outweighs the risk of thromboembolism overall

Plus the risk of ICH is highest when IV heparin is given as a bridge to oral AC

https://t.co/8PRR7FWMks

[Neal S Parikh MD @NealSParikhMD]

There is less buzz on this than I would have expected. Any deep dive threads out there? Makes me miss attending journal club, thats for sure!!

[NEJM @NEJM]

In a trial from China involving 1412 patients with acute ischemic stroke presenting within 4.5 hours, the percentage who had an excellent functional outcome at 90 days was 79.5% with reteplase and 70.4% with alteplase. Full RAISE trial results: https://t.co/t0spgl8xPz

[Neal S Parikh MD @NealSParikhMD]

@btolchin Thanks for sharing

[Neal S Parikh MD @NealSParikhMD]

@ShadiYaghi2 @ShuLiqi @NguyenThanhMD @JimSiegler @CamStroke @StrokeAHA_ASA @SetarehOmranMD @eva_mistry @m84gruen @VancouverStroke @nbavar Hasbled =0
V4 segment dissection
Whats your approach?

[Neal S Parikh MD @NealSParikhMD]

Interesting rare genetic csvd, for ddx of microbleeds

[JAMA Neurology @JAMANeuro]

Case report: the evaluation of a 44-year-old man with a history of headache, dizziness, and imbalance and imaging that showed lacunar infarctions and bilateral white matter hyperintensities. https://t.co/QMtxfzZGpS

[Neal S Parikh MD @NealSParikhMD]

Between Enrich and Switch, exciting year for acute ICH trials! The balanced discussion section, with compare/contrast of effect sizes, eligibility criteria, and endpoints, is a treat to read. https://t.co/KYRgJo0UXw

[Neal S Parikh MD @NealSParikhMD]

At this point, just put thrombectomy in the water!

https://t.co/aJ5XsOhUTN

[Neal S Parikh MD @NealSParikhMD]

@gdawod1 @StrokeMiami @uthsc @SemmesMurphey Congrats

[Neal S Parikh MD @NealSParikhMD]

@SerenaLOrr @SSNeuroMD @AANmember @Jorge_Ortiz_G @dr_jmartindale @ZachThrelkeldMD @shivika_ch @NezerSara @RaffaellaUmeton It is rather mutual

[Sara Schaefer, MD, MHS, FAAN @SSNeuroMD]

Lifelong friends and colleagues from the @AANmember ELP Class of 2023- you all continue to inspire me! @SerenaLOrr @Jorge_Ortiz_G @dr_jmartindale @NealSParikhMD @ZachThrelkeldMD @shivika_ch Morgan Jordan (@NezerSara @RaffaellaUmeton in abstentia)

[Neal S Parikh MD @NealSParikhMD]

@seanluomdphd Unlike mrs (0-6), utility weighted mrs has range 0-1, with utility reflecting patient perspective

[Neal S Parikh MD @NealSParikhMD]

Icymi
Enrich is finally out
https://t.co/0IALHWHA0I

[Neal S Parikh MD @NealSParikhMD]

Excited to head to #aanam and experience it through a new lens

[Neal S Parikh MD @NealSParikhMD]

Nice write up of bismuth (pepto bismol) toxicity causing CJD mimic

https://t.co/JCTSQUHkUf

A mimic not to miss!

[Neal S Parikh MD @NealSParikhMD]

https://t.co/nT4sEq3Wh1

Now that is some elegant epidemiology! HR 4, wow.

[Neal S Parikh MD @NealSParikhMD]

Logging in after a while to feel out the reaction to ATRESIA. Twitter did not disappoint. Wonderful to have the data! Now, want the same for secondary prevention, including for very brief episodes of device-detected AF (30sec-6 min).

[Neal S Parikh MD @NealSParikhMD]

https://t.co/Sw90JW28hF

Interesting perspective on health care and some sort of shocking pieces of knowledge

[Ashkan Shoamanesh @Ash_Shoamanesh]

1/6 🧵
Are you involved in the management of patients with #Afib or intracranial hemorrhage? Important recently published information contained in the following thread.

#neurotwitter #cardiotwitter #stroke #medtwitter #MedEd @McmasterStroke #stroke @PHRIresearch @MacDeptMed