Multicomponent reactions as a molecular prism: simple inputs are refracted into rich molecular diversity across the chemical space! Nice idea for the cover of the thematic issue on MCRs https://t.co/GqKHd01ZRk @BeilsteinInst@NeochoritisLab#MCRs
Can we learn a molecule how to hold still? Atropos and time are always interconnected, even from Greek mythology. A very nice MCR summit, with interesting chemistry here in olomouc, Czech republic
🚨New paper out in Nature Communications!
Scaffold hopping + MCR chemistry to design non-covalent molecular glues for the 14-3-3/ERα complex. A step forward in PPI-targeting drug discovery @University of SanFrancisco! @NeochoritisLab@NatureComms@UOC_gr
https://t.co/rezsSt5KQP
#EurJOC Diving into the Shielding Surfaces: Construction of Atropisomeric Axes via Multicomponent Reactions (Constantinos G. Neochoritis and co-workers) @UOC_gr@kneochor@NeochoritisLab#openaccess 🔓 https://t.co/C8EbENpiV7
Interrupting the route of known reactions can lead to novel chemotypes. By installing the oxo and acid functionalities on the same carbon, interrupted Ugi and Passerini reactions were discovered! https://t.co/10nNx1sR6b @NeochoritisLab@ELIDEK_HFRI@ACSPublications@JOC_OL#MCRs
C1 annulations are never outdated!
Thanks everybody for this smart way of utilizing formamide in a sustainable way!
10.3762/bjoc.21.13 @NeochoritisLab@UOC_gr @EmpireikionIdryma #MCRs#Neolab
We were very happy to be part of the 23rd Panhellenic Chemistry Conference, 2024. Our group thrived with 3 oral presentations, 2 flash poster presentations and 2 poster attendances. Looking forward to many more opportunities like this!
We are obligated to inform you about the achievements of @UOC_gr in the 3rd day of PCC 2024! Congratulations to Prof. M. Orfanopoulos for being awarded for his lifelong achievements in organic chemistry. Also congratulations to Prof. G. Vassilikogiannakis for his amazing lecture!
📣 Session 26 – The last speaker of the session is Ms Paraskevi Kleio ANASTASIOU who will talk about “MCR-Based Lipidoids”. Keep following us! 🔬💡
#EFMCISMC24#MedChem