🎉🎉📖Our work on how intracellular calcium dynamics shape the mucociliary epithelium during Xenopus embryogenesis is now puplished @NatureComms . You can read the manuscript here: https://t.co/eiJv9mscdk . Many thanks to all the reviewers for their constructive input. 🐸🔬
We are searching candidates for two positions in the lab (@GurdonInstitute& @GeneticsCam,@Cambridge_Uni ): Research assistant (starting Sep 2026 https://t.co/Wdq1VqguIH) and Postdoc(https://t.co/CGX4s6hvGD). Please visit University's webs for details and apply. Please spread!
We are searching for an enthusiastic scientist to join our team and establish annual killifish as a model system for early developmental biology and biophysics! @embl
Apply here: https://t.co/D21O7uO1r4...
Please re-post 🙏
Explant elongation initiates in the epithelium
A Research Highlight showcasing new work from @KatiaBarrett18, @ShalabhKAnand, Virginie Thome, Laurent Kodjabachian, Matthias Merkel, Pierre-François Lenne
https://t.co/eAlwQ4i7qe
Our paper is out!
We show how the extracellular matrix guides body axis formation in mouse—and possibly human—embryos during early pregnancy.
Grateful to @ZernickaGoetz@MZG_Lab for the chance to work with mouse, human, and stem cell–derived embryo models.
https://t.co/tEAc0f72o8
🎉🎉📖Our work on how intracellular calcium dynamics shape the mucociliary epithelium during Xenopus embryogenesis is now puplished @NatureComms . You can read the manuscript here: https://t.co/eiJv9mscdk . Many thanks to all the reviewers for their constructive input. 🐸🔬
New preprint🚨! Insertion of basal progenitors into an epithelium contributes to tissue morphogenesis and homeostasis. In this work, we study the role of intracellular calcium in multiciliated cell epithelial integration during Xenopus skin development. https://t.co/2Yu4rGsfpq
Warmest congratulations & thanks to brilliant member of our team @Caltech Wenqi Hu, collaborator @Roser Vento (not on X) & HDBR for a fantastic journey in bringing this unique resource. We hope it will be valuable as a reference point to build more powerful stem cell models
Super excited that our paper is out. It describes a new mechanism for dealing with tissue crowding that does not involve cell extrusion.
https://t.co/8CJzCS2MRl
New publication by Henrike Berns, lab members and the Schmidts lab @Uniklinik_Fr out at Disease Models & Mechanisms.
https://t.co/nyTqrCBxo5
Congrats to Henrike and thanks to the Motivate program, @SFB1453_NephGen and @CIBSS for funding. 🐸 #xenopus#wnt#birthdefects#kidney
Check out our new paper in @nature https://t.co/cI3YCh7X1g. We report genetic mechanisms of neural tube defects in patients. Spina bifida is also known as meningomyelocele (MM). Prior family-based and association studies found few linked genes, so we took a different approach.
Very happy that my final PhD paper focussing on the maturation of the primitive into the visceral endoderm and its impact on embryo survival in mice is now published: https://t.co/mCq52sAXd9
Huge thanks to my PhD supervisor & my collaborators for making this project possible
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New Preprint
Reptiles comprise ~23,000 species with an incredible range of diversity. The basis is laid during embryogenesis but severely understudied. We study the brown anole & describe its early embryogenesis for the first time:
https://t.co/y8GfSmQEwF
While we're at it: We are looking for 2 postdocs. One with experience in dev. Biol (pref. With mouse experience) and one with bioinformatics / modeling / multi-omics experience. Exceptional PhD candidates will be also considered for the project via IMPRS @mpi_ie recruitment.
Another preprint from the lab and a collaboration with Miriam Schmidts and her lab from @Uniklinik_Fr pediatrics. This work was carried out mostly by fantastic MD MOTIVATE student Henrike Berns. Funded by @dfg_public@CIBSS_UniFR and @SFB1453_NephGen.
https://t.co/XAOaZnx6TJ
We all take for granted that we can just reprogram cells- iPSCs are ubiquitous. But DYK that this was first demonstrated in frogs? Talk about a #xensight! Sir John Gurdon showed that a differentiated intestinal nucleus can be reprogrammed when put into an enucleated egg- in 1962!