PhD position ���� at CIIRC CTU, Prague: computational modeling of structural brain connectivity from diffusion MRI. Work on tractography, ML, and computational neuroscience with applications in cognition, aging, and neurological disease. Deadline: March 31. https://t.co/el4jfgScO1
Using post-mortem MRI and immunohistochemistry, Wesseling et al. show that brain donors with LATE-NC have lower amygdalar and hippocampal volumes than non-LATE-NC donors, even when correcting for regional p-tau, amyloid-beta, and alpha-synuclein burden. https://t.co/uKKpOB9AZG
There is still time to register for our upcoming webinar. Everything on postmortem imaging, this Thursday (Nov 6)!
Sign up here: https://t.co/OZbMwwVIhh
Agreed! Can’t count how many times I have seen alternative diagnoses first suggested by MRI findings or even refinement of “Parkinson’s” diagnosis, such as an atypical syndrome or even rarer things like PLA2G6 mutation. While volumetric tools often lag behind relative to presentation, we have more advanced tools now that allow us to directly measure the earliest stages of the disease like iron deposition in SN, depletion of neuromelanin, etc. As radiologists and ordering physicians, we have to move beyond the idea that we just check for strokes and tumors in patients with neurodegenerative disorders—we have the tools now to provide much more info. Diagnosis is multidisciplinary but imaging can be a powerful biomarker when obtained and interpreted correctly!
18F-FDG PET in detection of primary age-related tauopathy (PART) – Is there a role? Insights from an imaging-pathology correlation study
https://t.co/KwybJSTp8z
Last day of #AAIC25! Even though I couldn’t be there in person anymore, I was able to see @NeuroNiels shine on stage, as presenter and first-time session moderator. Very proud! 🤩
Ever wondered how small vessel disease is related with AD-proteinopathies in the medial temporal lobe? 🍤🧠 🔗 https://t.co/LND53ECdjK
In our new work we show:
✅CAA severity is linked to Aβ-plaques and tau
❌Arteriolosclerosis is not, but is associated with ePVS burden
Very happy to be in #Toronto for #AAIC25! Great kick-off with the #AIC preconference, @EmmaCoomans presenting the year-in-review. Also, come visit my poster AIC-310 with lots of MRI-pathology studies!
Using post-mortem in situ MRI, Wesseling et al. show that brain donors with LATE-NC have lower amygdalar and hippocampal volumes than non-LATE-NC donors, even when correcting for regional phosphorylated tau, amyloid-b, and a-syn. https://t.co/z7zmVvvarl
🚨 New manuscript from the team! Cross-disease assessment of volume change and pathological accumulation in hippocampal subfields. First-first by @maud_bouwvrouw! 🥳
https://t.co/uG9yYLpT55
So excited and honored to be invited to present the opening plenary at #AIC2025 this year in Toronto! 🧠
🙏 I would be very grateful if you could help me gather the most inspiring papers (including your own!) of the past year by completing this survey: https://t.co/wjzdmNmH9f
Always my favourite post at the beginning of the year:
Registration for our course “Biomarkers for neurodegenerative diseases” is now open!
This year’s edition takes place at @UCLIoN in central London on May 12-16.
https://t.co/ix28Tw1VHQ
We live in a state of perpetual dissociation from the almost unbearable wonder of being alive. But if we fell asleep each night remembering “the singularity we once were” and awoke each morning with the bright awareness that every atom in our bodies can be traced to one of the first stars... we would be too wonder-struck by the miraculousness of it all to deal with the mundane. The dishes have to be washed and the emails have to be written, so we avert our eyes from the majesty and mystery of a universe that made them in order to look at itself, from the majesty and mystery of what we are. https://t.co/R55qagtn6U
First first-author manuscript of PhD student submitted in early October, got desk- rejected after the journal was unable to find reviewers (20+ invitations sent out). Not the most motivational way to start you academic career! #butPIstillproud
@social_brains “One surprising connection I’ve noticed that humans might not fully appreciate is the interplay between quantum mechanics, consciousness, and the origins of life—an intersection that is still largely speculative but intriguing nonetheless.”