Samuel Mackenzie MD PhD

Pediatric #neuromuscular doc, amateur scientist @URneuroscience, runner, chess enthusiast, dad. #Meliora

[Samuel Mackenzie MD PhD @NotoriousEMG]

New pod, who dis? Co-hosting with the incomparable @OligoclonalBand. Music by @zach_london. Drops monthly. Strap in.

Immature Brains: A Child Neurology Podcast https://t.co/A6PRMqaIkO via @rss

[Samuel Mackenzie MD PhD @NotoriousEMG]

This is wild. Smells like a class action lawsuit to me.

[Sholto David @addictedtoigno1]

Earlier this week I posted an example of a fake western blot provided by ThermoFisher to demonstrate the validity of a p53 antibody. I considered it an amusing curiosity. In fact ThermoFisher has systematically manipulated antibody validation data. Short Thread... 🧵

[Sholto David @addictedtoigno1]

Surprised to discover that Thermo Fisher appears to show a fake western blot for the validation of one of their p53 antibodies. I've added a diagram to show the very similar bands. This does not appear to be one of the "published figures", but their own internal data.

[MP Arizona☀️🏳️‍🌈💙🌵🐕🐕‍🦺🫂💦🏜🐟🌴🎙🌎🌻♍️🌊 @AzPetrich]

This is my favorite scene from The Bible.

[Samuel Mackenzie MD PhD @NotoriousEMG]

You too can donate! Support families who have lost a child. https://t.co/JxkrofxXl9

[Ali Christy, MD, PhD @OligoclonalBand]

Are you traveling to the @AANmember annual meeting today?

What a great time to listen to an incredibly goofy BONUS EPISODE of Immature Brains: A Child Neurology Podcast, where we pledge drive for @Child_Neurology with Kim Hindery!
https://t.co/sq7rdPnwhS @NotoriousEMG

[Ali Christy, MD, PhD @OligoclonalBand]

Are you traveling to the @AANmember annual meeting today?

What a great time to listen to an incredibly goofy BONUS EPISODE of Immature Brains: A Child Neurology Podcast, where we pledge drive for @Child_Neurology with Kim Hindery!
https://t.co/sq7rdPnwhS @NotoriousEMG

[Dov Kleiman @NFL_DovKleiman]

Heartwarming: When Dan Orlovsky's autistic son, Madden, joined NFL Live and made everyone on set cry while highlighting Autism Awareness Day with his drawings.

You can just see how proud Dan is of his son.

What a special moment captured 🥹❤️

[Oded Rechavi @OdedRechavi]

Every PI

[Samuel Mackenzie MD PhD @NotoriousEMG]

@OligoclonalBand @acostalmd Looks like my CME surveys.

[Denis Wirtz @deniswirtz]

Here is our updated database of grants for early careers researchers in all fields.

It goes way beyond traditional NIH and NSF funding opportunities. We list 428 types of grants.

Download it here: https://t.co/RGXGrdp2uf

[Cameron 🇺🇸 🗽🦅 @CameronCorduroy]

this is what actual national suicide looks like btw

[Dr. Catharine Young @DrCatharineY]

We were told NIH funding cuts were about eliminating DEI.

But the data now shows grants are down across nearly every field of medicine: cancer, diabetes, mental health, brain disorders.

With the greatest cuts hitting Alzheimer’s research, down more than 50%.

[Dr. Catharine Young @DrCatharineY]

A deliberate erosion of the scientific enterprise begins by eroding the workforce.

In 2025 alone, the U.S. lost more than 10,000 STEM Ph.D.s across 14 federal agencies. The brain drain is real.

[Samuel Mackenzie MD PhD @NotoriousEMG]

Our final episode of season 1 is out! Thanks to all our listeners and to @kuntal_sen_ for joining us! See you again in June. @OligoclonalBand https://t.co/zHOVTnV0J7

[Samuel Mackenzie MD PhD @NotoriousEMG]

Reposting this is probably rewarding some bot farm in Indonesia, but I don’t care.

[Interesting things @awkwardgoogle]

In a world where you can be anything, be a number 50

[Jonathan Reiner @JReinerMD]

In the fall the administration held a press conference attended by President Trump, FDA Commissioner Makary, and HHS Sec Kennedy where Lekovorin was touted as an exciting treatment for autism. But when the FDA completed their full review of the drug, they approved it only for a type of brain folate deficiency that’s only ever been identified in about 50 kids. Normally breakthrough announcements are made after data proves efficacy, not before. Doesn’t work that way in this administration.

[Denis Wirtz @deniswirtz]

NIH is not issuing awards. You may think that it's because they it is coming up with new directions of research...The apposite is true.

Here is a graph showing how many fewer new funding opportunities that NIH has posted over time.

-91%, a trend that started on Jan 2025.

[Denis Wirtz @deniswirtz]

Federal funding for US biomedical research is moribund.

Since October 1 2025, NIH is -80% in new grants and -70% in values (total dollars).

Labs are closing down and researchers are leaving science.

To what end?

[Jerome Adams @JeromeAdamsMD]

Today’s American History Lesson: Puerto Rico has been part of the U.S. since 1898, and Puerto Ricans have been U.S. citizens since 1917 🇵🇷 🇺🇸

We’ve cheered many non-Americans at the #SuperBowl. Bad Bunny isn’t one of them.
🏈 🎤

[Samuel Mackenzie MD PhD @NotoriousEMG]

Listen to Episode 9: Minneapolis, Jean Cady Solis, and febrile seizures on @rss https://t.co/O6BTJJ5ImH @OligoclonalBand @kidbraindocMD