Nutty Witty

Tomorrow never comes until is too late!!!

[꩜ @faeslily]

me

[Nutty Witty @NuttyWitty0]

#FinalBotanera

[Nutty Witty @NuttyWitty0]

@AztecaDeportes

#finalbotanera
Desde pequeños somos pumas

[Bryan Johnson @bryan_johnson]

This is it.
Everything learned spending millions on longevity.

From: Your Immortal Unc and Auntie.
To: Our Immortal nieces and nephews.

0. Sleep is the world's most powerful drug.
1. Be in your bed for 8 hours
2. Same bedtime every night, any time before midnight
3. Don’t eat right before bed
4. Calm foods for dinner
5. No screens 1 hour before bed
6. Avoid added sugar (be aware it’s in everything)
7. Avoid all things in an American convenience store
8. Avoid fried foods
9. Shoes off at the door
10. Eat whole foods, particularly veggies fruits nuts legumes berries
11. Walk a little after meals or air squats
12. Get your heart rate high routinely
13. Lift heavy things
14. Stretch daily
15. Water pik, floss, brush, tongue scrape, morning and night
16. Make an effort to drink water
17. Get sunlight when you wake up (UV is low)
18. Protect skin in midday sun
19. Stand up straight
20. See at least one friend once a week
21. Avoid plastic where you can (in all things)
22. Circulate air in rooms
23. When stressed, breathe, learn to calm your body
24. Go to the dentist
25. Avoid sitting for long times
26. Protect your hearing, the world is too loud
27. Alcohol is bad for you
28. Finish coffee before noon
29. Avoid bright lights after sunset
30. If obese, look into a GLP
31. Sleep in a cold room
32. Texting while driving is dangerous
33. Turn off all notifications
34. Limit social media use
35. Don’t smoke anything
36. If you struggle to sleep, read a physical book before bed
37. 1 hour before bed have a calm wind down routine: bath, read, light walk, listen to music
38. The body is a clock and loves routine. Have a daily morning and evening schedule.
39. Avoid long distance travel where you can
40. Baby steps first: incorporate new things slowly
41. Do less… most things don’t work.

Bonus points if you get your blood checked.

Start here, it will change your life.

[Bryan Johnson @bryan_johnson]

People mistakenly believe peptides are only good.

Peptides can be bad, too.

They can cause adverse effects. Some dangerous.

I did a peptide experiment and measured its effects in my body. The results are complicated.

I tried a peptide called CJC-1295.

It pushed my growth hormone up by ~8x. That’s good. That’s what it was supposed to do.

But, it also came with adverse effects:
> increased my morning fasted blood sugar up 20%
> increased stress hormone by 12%
> tanked my REM sleep by 23%
> made my pancreas work 53% harder and was still losing to rising blood glucose
> increased my insulin resistance by 50%

These were the most obvious side effects, and I only ran a very narrow panel for this experiment.

So I’m sure there’s more.

I stopped after two doses, without even reaching the intended target dose.

For those of you new to peptides, your body sends instructions to itself using tiny chemical messengers called peptides. There are thousands of them.

For example, GLP-1s are drugs that take an existing class of short-lived peptides and modify them to extend their activity duration, which turns them into drugs, following rigorous clinical testing.

CJC-1295 is one of those peptide-drugs. It tells your brain to release more growth hormone. Growth hormone is your body's signal to build muscle, repair tissue, and recover.

However, and like most grey market peptides, CJC-1295 did not succeed its clinical trial, and hence never became an “official” drug.

There is a version called CJC-1295 with DAC. DAC is an attachment glued onto the peptide that makes it last for days in your body instead of hours. One shot, longer effect, just like GLP-1s.

Why people use it: more growth hormone could mean better recovery, leaner body, faster healing.

The experiment I completed.

Two injections a week of CJC-1295 with DAC:
> 1.2 mg
> 1.8 mg

48 hours after the first injection I was nearly comatose. It felt like severe jet lag, the type you’d feel after traveling nine time zones. My sleep was wrecked and I felt continuously awful.

My REM sleep dropped by 23%. REM is when your brain processes memories and repairs itself. Less time for my brain to repair itself. During the experiment, I never felt rested and always fatigued.

Why we chose CJC-1295 with DAC.

Some will say we picked the wrong peptide. They will say I should have used a different version, CJC-1295 without DAC, mixed with another peptide called Ipamorelin. We went with CJC-1295 with DAC instead as it has the most controlled studies.

CJC-1295 with DAC has 2 controlled trials in healthy adults. Ipamorelin alone has 1 controlled trial in healthy adults, plus 1 study that failed when they tried it on bowel surgery patients. The mix of the two has zero controlled trials.

On Ipamorelin, it copies a chemical called ghrelin, the one that makes you hungry. On its own it gives you a quick burst of growth hormone that fades fast. It does not keep your longer acting growth signal (called IGF-1) up. Clinics mix Ipamorelin with CJC-1295 no-DAC because the two together are supposed to work better. But we don’t know if that’s accurate because we don’t have trial data.

This is a problem with peptides. Almost none of them have been tested properly. We are flying blind. Most of what people use is based on what someone said online, what a clinic claims, or what a friend reports from their subjective feelings.

Peptides have the potential to be great when well-studied.

[Bryan Johnson @bryan_johnson]

Society was built to make money.

Indifferent to your health and sanity.

For example, we did not evolve to:
+ sit 10 hours a day
+ have our attention fractured 300 times daily
+ compare ourselves to millions of others
+ travel 9 time zones in 13 hours
+ tolerate sounds above 85 dB causing hearing loss
+ outsmart algorithms hijacking our reward system
+ breathe fine particulate air pollution
+ live under 16+ hrs of artificial light a day
+ have 3 courses of antibiotics before age 2
+ eat ultra-processed foods for 60% of daily calories
+ consume 17 teaspoons of added sugar a day

So if you're feeling down in the dumps, maybe fatigued, a little or a lot depressed, anxious, that's why.

[Nutty Witty @NuttyWitty0]

@asparagoid Midnight library 👌

[Valerie Anne Smith @ValerieAnne1970]

So, the Measles vaccine caused 30X the deaths than Measles itself… got it.

[Bryan Johnson @bryan_johnson]

This is her vaginal microbiome report. 100/100 score.

Top 1% of all vaginas.

Her sample is dominated by the single most protective bacterial species a vagina can host (Lactobacillus crispatus).

Only about 25-30% of reproductive age women globally are L. crispatus-dominant, and “dominant” usually means above 50%. Kate is at 98.7%.

The lab found nothing bad to report. (no gardnerella, Candida, STIs, opportunistic pathogens, aerobic vaginitis markers, etc.)

This is linked to lower risk of BV, UTIs, yeast infections, HPV persistence, HSV-2 and HIV acquisition, preterm birth, and improved IVF outcomes.

A vaginal microbiome is downstream of everything: sleep, glucose control, stress, gut health, sexual health, immune function, what you eat, and what you put in it.

[Mario Nawfal @MarioNawfal]

🇺🇸 Women in the U.S are having fewer children than ever before.

The fertility rate has fallen to just 53.1 births per 1,000 women aged 15–44, the lowest in history.

The replacement rate, to keep the population stable, is roughly 2,100 births per 1,000 women over their lifetimes.

Thanks feminism, great job extinguishing humanity

Source: CDC

[Nutty Witty @NuttyWitty0]

@undervaluedstxs @JamesWynnReal 😂 😂

[Ted @TedPillows]

People think the stock market still has plenty of upside.

I don’t buy it.

This feels like the final stage, everyone piling in before the rush for the exits.

Give it some weeks and bookmark this.

[Nutty Witty @NuttyWitty0]

@TedPillows bookmarked buddy!! :)

[Nutty Witty @NuttyWitty0]

@ZeroHedge_ I will keep grinding, cheers

[Bryan Johnson @bryan_johnson]

Pregnancy is severely underappreciated in our society. Most women don't get the guidance they need from doctors. Self experimentation gives the power back.

[Nutty Witty @NuttyWitty0]

@DorisDi3 @ZeroHedge_ @Tradingalpha_ My bad, already saw it thanks ✌️

[Nutty Witty @NuttyWitty0]

@DorisDi3 @ZeroHedge_ @Tradingalpha_ But which manual are you talking about, do you mind namening it please so I can look it up ☺️ cheers

[Clash Report @clashreport]

Pete Hegseth quoted a fake Bible verse from Pulp Fiction during a Pentagon sermon.