Oxidant and Inflammation Biology group

Respiratory Diseases 🤧🫁❤️🤰| RMIT University @RMIT_CRSH | Lab Head Prof Stavros Selemidis @noxbiology

[Stella Liong @StellaLiong_]

Our new paper in @ScienceAdvances shows that TLR7, a viral RNA sensor, amplifies influenza-mediated vascular inflammation and dysfunction in pregnancy, leading to adverse maternal and foetal outcomes. https://t.co/g6zG2bDjxy

@Gemmagoesviral @noxbiology @OXIBgroup @RMIT_CRSH

[Oxidant and Inflammation Biology group @OXIBgroup]

Dr Mark Miles (@DrMark91) represented OXIB at @ASImmunology, where he presented his latest research on the dual role of TLR7 in regulating inflammation and lung function during viral respiratory infection.

#ASI2025 #ASImmunology

[Centre for Respiratory Science and Health @RMIT_CRSH]

Xinyue from @OXIBgroup is determining the role of CD4+ T cells in mediating vascular inflammation and dysfunction during gestational influenza infection

[Centre for Respiratory Science and Health @RMIT_CRSH]

Ameanah from @OXIBgroup is exploring the lipdifferential temporal immune responses to influenza A virus and pattern recognition receptors stimulation in lung epithelial cells and macrophages

[Centre for Respiratory Science and Health @RMIT_CRSH]

Paneet from @OXIBgroup is investigating how prenatal and early life viral infections disrupt the blood brain barrier integrity and increase the risk of long-term neurodevelopment abnormalities

[VIIN @The_VIIN]

🫁 Excellent work on Influenza A virus driving TLR-dependent inflammatory responses in non-small cell lung cancer. This exciting research was brought to us by Isabella Rosano from @RMIT
#YoungVIIN2025 #VIINYIS

[Oxidant and Inflammation Biology group @OXIBgroup]

@The_VIIN @RMIT Great work, Isabella!

[Oxidant and Inflammation Biology group @OXIBgroup]

Last Friday, Isabella had the opportunity to showcase her Honours project on how influenza A virus drives TLR7-dependent responses in non-small cell lung cancer at the #YoungVIIN2025 symposium. It was a great moment for Isabella and our lab!

@The_VIIN #viinyis #IAV #flu #cancer

[Oxidant and Inflammation Biology group @OXIBgroup]

Great work Isabella on presenting your exciting data on the effects of influenza A virus infection in non-small cell lung cancer.

#Honours #RMIT #IAV #lungcancer

[Centre for Respiratory Science and Health @RMIT_CRSH]

Congratulations to Dr Stella Liong and Dr Hao Wang for receiving the Outstanding Contribution to Research & Innovation (Early Career) and Certificate of Commendation, respectively. Their hard work was recognised today at @RMIT SHBS Staff Forum.

[Centre for Respiratory Science and Health @RMIT_CRSH]

Removing TLR7 reduced these sex-based differences, suggesting TLR7 may shape how males and females fight RSV.

#RSV #TLR7 #Immunology #SexDifferences

https://t.co/2yG32o4muQ

[Centre for Respiratory Science and Health @RMIT_CRSH]

#ResearchSpotlight: New research led by @DrMark91 and @noxbiology from @OXIBgroup reveals TLR7 helps drive stronger immune responses to RSV infection in females, including higher cytokine and antibody levels.

https://t.co/2yG32o4muQ

[Oxidant and Inflammation Biology group @OXIBgroup]

Today was a beautiful day to be pushing the boundaries of science!

#OXIB #Research #Science

[Oxidant and Inflammation Biology group @OXIBgroup]

Today was a beautiful day to be pushing the boundaries of science!

#Honours #PhD #Research

[Centre for Respiratory Science and Health @RMIT_CRSH]

It drives harmful lung inflammation and dysfunction early on but helps to control Th2-mediated chronic airway hyperreactivity. #Influenza #Immunology #TLR7

https://t.co/FjarO0EsHb

[Centre for Respiratory Science and Health @RMIT_CRSH]

#ResearchSpotlight: Research led by @DrMark91 and @noxbiology in collaboration with @UniversitySA and @TrinityCollege uncovers a double-edged role of TLR7 in influenza infections. 🦠

[Oxidant and Inflammation Biology group @OXIBgroup]

Congratulations to @DrMark91 on being awarded the Maxwell Eagle Endowment Award for Cancer Research. A great note to end the year on!

[Natalia Sampaio @DrNatSampaio]

Still a lot to learn about RNA-sensing in virus infection! Ameanah El-Hennawi from @RMIT presented some unexpected RIG-I and TLR7 responses to #flu infection in macrophages vs epithelial cells @The_VIIN #VIINYIS #YoungVIIN2024

[Natalia Sampaio @DrNatSampaio]

More great Science Bites at @The_VIIN #VIINYIS #YoungVIIN2024. Thomas Huttmann from @RMIT_CRSH TLR7-linked sex-diffs in response to #RSV, a critically rising airborne pathogen; and Andrew Verich from @KirbyInstitute employing #machinelearning to improve diagnosis of #gonorrhoeae

[Dr Gabriela Khoury @GabrielaKhoury]

More work on TLR7 from @RmitSciences @ResearchRMIT Great talk from Honours student Ameanah El-Hennawi who's looking at the role of TLR7 in macrophages during Influenza infection #VIINYIS #YoungVIIN2024 @The_VIIN