Ordureau_Lab

[Trends in Biochemical Sciences @TrendsBiochem]

Two other Reviews in the October issue highlight #E3ligases in 1) #ProteinQualityControl degradation and 2) how mutations of them and other ubiquitin machinery impact #neurodevelopment and #neurodegeneration (@ColinZenge @Ordureau_Lab).

[jobRxiv @jobRxiv]

Postdoctoral Fellow in Cell Biology, Biochemistry or Proteomics (New York).

Come join us as a Postdoctoral Fellow to study #Ubiquitin, #Autophagy, #Biochemistry, and #Proteomics at the Sloan Kettering Institute in New York.

https://t.co/sPAQzEU96O

#...
https://t.co/sPAQzEU96O

[Molecular Cell @MolecularCell]

The picky mTORC1 in metabolic enzyme degradation https://t.co/nrMNFSh1SH

[Green Lab @GreenLabJHMI]

We’re excited to share our study in @CellCellPress on the role of the MAP3 kinase ZAK in UV-induced apoptosis led by @2primehydroxyl! We studied cell signaling kinetics following UV-damage and found that ZAK drives apoptosis via ribosome collisions. https://t.co/A3RjOkq62k

[Ordureau_Lab @Ordureau_Lab]

Very happy to see this study conducted with @GreenLabJHMI, @RegotLab @CantleyLab labs, published. Massive opus from Niladri (@2primehydroxyl), revealing the ribotoxic stress response drives UV-induced apoptosis. Congrats to Niladri and everyone involved!
https://t.co/dkoQbmRwmJ

[Sara Šepić @sepic_sara]

Check out the study on the first identified human protein whose stability is regulated via Pro/N-degron and CTLH E3 ligase

[Ordureau_Lab @Ordureau_Lab]

Fun collaboration with the @AnLab_MSKCC - #Ubiquitin #mTOR #Metabolism

[Molecular Cell @MolecularCell]

Online Now: mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway https://t.co/a9lxS3uqtO