SijbrenOttoLab

Systems Chemistry Group at the University of Groningen. Transition of chemistry to biology (incl. origins of life, synthetic life), complex systems.

[Nature Catalysis @NatureCatalysis]

Selection for photocatalytic function through Darwinian evolution of synthetic self-replicators https://t.co/2P5ugAr5zh

[Omer Markovitch @OmerMarkovitch]

How to select primitive / synthetic replicators based their photocatalysis? Check out our manuscript just published in @NatureCatalysis :
https://t.co/N9BJYoKkJj

@KaiLiu125348 @Ottolab
#OoL #Origins #Prebiotic #Evolution

[J. Am. Chem. Soc. @J_A_C_S]

Light-Mediated Interconversion between a Foldamer and a Self-Replicator | Journal of the American Chemical Society @LMU_Muenchen
@StratinghInst
@univgroningen
#Foldamer #SelfReplicator #LightMediated #Interconversion https://t.co/D5ujbvgr4n

[J. Am. Chem. Soc. @J_A_C_S]

Simultaneous Formation of a Foldamer and a Self-Replicator by Out-of-Equilibrium Dynamic Covalent Chemistry | JACS @LMU_Muenchen @StratinghInst @univgroningen #Foldamer #SelfReplicator #OutofEquilibrium #Dynamic #Covalent #Chemistry https://t.co/1LSDO2dYkQ

[Kai Liu @KaiLiu125348]

What can dissipative chemistry bring us? In our recently published paper, we demonstrate the emergence of mechanical function from disspative droplet systems. @NatureChemistry https://t.co/kV5mVCTjOz

[Communications Chemistry @CommsChem]

Probe the non-enzymatic macrocyclization reaction of benzene-1,3-dithiol in the presence of peptide condensates by reactive Martini simulations, reported by @CG_Martini @OttoLab @csbrasnett
https://t.co/Xtkyb3MXJO

[Yannick Geiger | @yannickgeiger.bsky.social @YannickGeiger1]

A little peak into last year's work with @Juntian74804617 and @Armin__Kiani in @OttoLab . You think our replicators are already complex enough? Then brace yourselves, Marcel has put 2-3 of them in competition and we had to make sense of their behaviour...

https://t.co/alj4wARR41

[Top Science @isciverse]

This study introduces a new mechanism that decreases error rates and corrects errors in synthetic self-replicating systems driven by self-assembly. @angew_chem #chemistry #Science #chemed #Technology #news @OttoLab @OmerMarkovitch

https://t.co/qPPaJ7ntDn

[ChemEurJ: Chemistry - A European Journal @ChemEurJ]

Generalist versus Specialist Self-Replicators (Sijbren Otto and co-workers) @seilenfranzli @Nitrogeno_N @GuilleMonrealS @OttoLab @StratinghInst https://t.co/b5cHy412Pm

[Angewandte Chemie @angew_chem]

Binding of Precursors to Replicator Assemblies Can Improve Replication Fidelity and Mediate Error Correction (Sijbren Otto and co-workers) #openaccess @OttoLab @OmerMarkovitch https://t.co/lb0UMA7b6x

[SijbrenOttoLab @OttoLab]

Our newest paper is out!!!
Here we show how a replicator system can correct errors during replication. Congrats @OmerMarkovitch and @Juntian74804617 🥳
Check it out: https://t.co/hk4nm6XcmZ

[The Goldup Lab @GoldupLab]

Fancy doing some shiny new chemistry in a shiny new building? If so, come and join us @UoBChemistry 😀 We have fully funded PhD positions available working on…

[SijbrenOttoLab @OttoLab]

Sijbren and Kayleigh were interviewed by @NEMOkennislink at the occasion of the 70th birthday of the famous Miller-Urey experiment. Check it out if you speak Dutch - or know how to use Google translate!

[Babis Pappas @pappas_babis]

We have a PhD position on phosphate-driven non-equilibrium assemblies @ERC_Research funded at @FitFreiburg @UniFreiburg. Deadline for application is 15/01/24.

More information can be found here: https://t.co/0nwizkD0mW

RT appreciated!

[Omer Markovitch @OmerMarkovitch]

Can a purely chemical system reduces its #errors during #replication? And even "correct" them?. In this latest @ChemRxiv we are claiming YES to both questions!
https://t.co/PA7qqcJdhx @OttoLab @Juntian74804617

[SijbrenOttoLab @OttoLab]

@AlexBlokhuis @StratinghInst Thank you Alex!

[SijbrenOttoLab @OttoLab]

@FeringaLab Thank you so much! Looks like there is some cyclic behaviour, one ERC every six years... Now it's clear why we didn't get it last year😏

[SijbrenOttoLab @OttoLab]

More details about the proposal on the university website👇
https://t.co/MYvmEUShT3

[SijbrenOttoLab @OttoLab]

BREAKING💥Ottogroup was awarded an ERC synergy grant, together with @AshkenasyLab and the groups of Eörs Szathmáry and Andrew Griffiths. Greatest thanks to all collaborators, it was a long and winding journey but it paid off!

[SijbrenOttoLab @OttoLab]

More PhD and also post-doc positions will open - especially prospective post-docs are encouraged to get in touch with Sijbren soon. We offer high-quality research in a multidisciplinary field and (soon) in a brand-new building in Groningen!