Outer Biosciences

Building the future of human skin health

[Outer Biosciences @OuterBio]

Read the bioRxiv preprint here: https://t.co/Inchbw2pe7

[Outer Biosciences @OuterBio]

Today we're introducing Yuna, our platform for discovering skin bioactives.

Yuna keeps living, full-thickness human skin viable and observable for four weeks, with native tissue architecture preserved.

That duration matters a lot more than it sounds. Key biological processes such as collagen remodeling, barrier restoration and tissue repair, sustained inflammation, and cumulative damage can take longer than a week to fully play out, meaning shorter studies may capture only part of these processes or how interventions behave in human skin over time.

Yuna widens the window, and pairs it with machine learning trained on our own tissue data rather than public datasets. Every experiment sharpens the next prediction.

Our preprint is now on bioRxiv. It shows Yuna sustaining three distinct skin biologies across four weeks (psoriasis-like inflammation, senescence in aged donor tissue, and UVB stress response) and returning the known answer in each case when challenged with an established intervention.

We partner with select biotech, pharma, beauty and personal care companies who need human-relevant skin data. If that's you, we'd like to hear from you.

Read more about Yuna here: https://t.co/hMzOGl62Kf