PagèsLab

DNA damage and genome instability group at @crcm_marseille. #DNAdamage, #TranslesionSynthesis, #HomologousRecombination, in bacteria & yeast

[PagèsLab @Pages_Lab]

Exciting opportunity: we are hiring a postdoctoral fellow for a fully funded 2-year position!

[PagèsLab @Pages_Lab]

Amazing view from the 24th floor of the Sorbonne tower at the 7th German-French DNA Repair Meeting! Excited to give my talk tomorrow!

[PagèsLab @Pages_Lab]

open access version here: https://t.co/jyDp3Sp8an

[PagèsLab @Pages_Lab]

New paper out! We show that RecBC remodels single-stranded DNA gaps to protect them from ExoI (sbcB) 3′-5′ exonuclease degradation during replication of damaged DNA.

https://t.co/84YUdHnxXx

[CNRS Biologie @CNRSbiologie]

#ResultatScientifique 🔎| Découvrez la dernière publication de Vincent Pagès et ses collaborateurs ⤵️

🤝 @CNRS @CNRS_dr12 @crcm_marseille @Pages_lab
📕 @NAR_Open | https://t.co/ygykXHJhyF

[PagèsLab @Pages_Lab]

Our key findings:
-DNA polymerase η swiftly bypasses UV-induced lesions at the replication fork.
-Post-replicative gaps allow Translesion Synthesis (TLS) to compete with Damage Avoidance (DA), reducing mutagenicity.
-Gap extension by Exo1 nuclease favors DA and reduces TLS

[PagèsLab @Pages_Lab]

Our latest article, in collaboration with Helle Ulrich, explores how the timing of lesion bypass and gap processing impacts genome stability.
https://t.co/auz3KycWWW

[PagèsLab @Pages_Lab]

How does Pol IV overcome strong replication blocks in E. coli? Our latest study with @JoeLoparo uncovers a bipartite clamp interaction that helps Pol IV compete with Pol III, enabling efficient TLS at stalled forks and reducing mutagenesis.
https://t.co/Ut1NnHJvAo

[CRCM - Cancer Research Centre of Marseille @crcm_marseille]

🎉 The CRCM wishes you a Happy New Year! 
✨ May this new year be rich in discoveries, collaborations and successes 🦠

[Sharon B. Cantor @CantorLab]

Join the conversation and get your abstract in soon!

[Institut Curie @institut_curie]

📣 Register now until March 2nd, 2025, for the next Genome Instability and Human Disease international course at @institut_curie! Gain knowledge of mechanisms ensuring genome stability, from fundamental molecular pathways up to large scale approaches.

▶️https://t.co/WhxrvzMkSQ

[McVeylab @mcveylab]

The versatile REV7 protein plays important roles in cancer development and chemotherapy resistance. Our lab's own Lara Maggs just published a comprehensive review of REV7 biology in a Frontiers issue collated by @lab_chatterjee. Check it out here: https://t.co/tBOCADKFXF.

[PagèsLab @Pages_Lab]

Recruiting a postdoc to work on our yeast project

[Cyril Ribeyre @Cyril__R]

We are organizing a FREE small symposium on DNA replication and replication stress on December 2nd and 3rd in Montpellier, France. Slots are still available for posters and talks. More info here: https://t.co/X4AAGd0Nq1

[ConstantinouLab @ConstantinouL]

We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: https://t.co/ysMXHk7ApK

[FEBS Letters @FEBS_Letters]

🧬#DNAreplication: the mystery unravels🧬
Looking forward to the EMBO/EMBL Symposium #EESreplication, which starts today!

@EMBLEvents

[CRCM - Cancer Research Centre of Marseille @crcm_marseille]

🧬 Join us tomorrow for an exciting seminar by @Terence_Strick, Full Professor at @ENS_ULM! He will present on “A DNA scaffold to study the repair of double-strand breaks.”
🗓️ Tuesday, Sept 24th, 2024
🕚 11:00 AM
📍 IPC2 Amphitheater
💻 Zoom: https://t.co/6GwLceYUDk
#DNArepair

[Yasu Daigaku @DaigakuYasu]

New review article, written by Lewis Bainbridge @LewisBainb53268 and me. This article
focuses on the diverse roles of replicative DNA polymerases during genome replication and their molecular basis.
https://t.co/K9OsF4x1uT

[PagèsLab @Pages_Lab]

My 1st @nanopore sequencing. Love the summer when I can spend some time at the bench...

[Felix Prado @Felix_Cabimer]

I am glad to share our last work uncovering MCM/RNR interactions and their role in genome integrity

https://t.co/lGBaIemouW