Paraish S. Misra, M.D.

Clinician Scientist and Transplant Nephrologist at the @CUSM_MUHC studying CKD, Diabetes, Pluripotent stem cells, and Transplantation (He/him/his)

[Jeffrey Millman @JeffreyRMillman]

🚨 New paper from our lab in BMC Methods!
We describe a simple, rapid, and cost-effective method to identify subcutaneously transplanted pancreatic human islet grafts using dithizone (DTZ) staining. #diabetes #stemcells #islets 🧵

https://t.co/wM7n2lAQM7

[Prof. Akiko Iwasaki @VirusesImmunity]

I wrote this piece to promote thoughtful, respectful, and rational engagement with controversial science topics. I hope it fosters constructive dialogue in the scientific community—thank you for reading and sharing 🙏🏼 @NatRevImmunol

https://t.co/iSdbikwy9p

[Diabetes Center at UCSF @AtUcsf]

Congratulations to @Tang_Lab_UCSF postdoc @RobertoCG96, recipient of a @BreakthroughT1D 2026 advanced postdoctoral fellowship for "Engineering Treg Signaling to Develop an Effective Cell Therapy for Type 1 Diabetes"

[Build Canada @build_canada]

One visit to a Montréal deli confirms this 🥪

We do a lot of things well in 🇨🇦

✅Ottawa leads North America on Quality of Life
✅We lead the OECD Better Life Index on health
✅We’re the happiest nation in the G7
✅Vancouver leads North America in EIU’s Global Liveability Index

[Leonardo V. Riella @LVRiella]

An extraordinary story of transplantation @mgh_transplant @MGBKidneys @MassGeneralNews
Olivia received a kidney from her mother over 50y ago, and today, that kidney is 103 years old.
She continues to thrive and now supports other patients on their journey.
https://t.co/ISc5ncqkvW

[Maya Inspired @Maya4Rights]

The NGN3 persistence insight is a game-changer for steering away from enterochromaffin cells. And honestly, we are finally getting closer to viable beta cell replacement therapy.

[Daniel J Drucker @DanielJDrucker]

Preclinical and clinical studies indicate that NKX6.1 mRNA expression could serve as a biomarker to predict islet graft function independently of islet mass, purity, and viability #transplantation #T1D @ScienceTM https://t.co/oOc67q0FkU

[Daniel J Drucker @DanielJDrucker]

Insights from derivation of human IPS #stemcell derived islet-like or off-target enterochromaffin (EC)-like cells in the pancreas #diabetes @UHN_Research https://t.co/LWfmj6zXLt

[Cristina Nostro @mcnostro]

I'm thrilled to share our recent work! Congratulations to @ParaishM and everyone involved @MCNostroLab @McEwenInstitute @UHN_Research @physiologyuoft @GPavlinkova

[Paraish S. Misra, M.D. @ParaishM]

Grateful for funding from @CIHR-IRSC @uhnfoundation #Howard Webster Foundation @BreakthroughT1D @KidneyCanada #KRESCENT @UofT_DOM #CSTP @cst_transplant @CIRTNetwork @BBDC_UofT @CzechAcademy #CzechScienceFoundation
This work wouldn’t be possible without their support.

[Paraish S. Misra, M.D. @ParaishM]

Excited to share our new paper in Nat Comms on how human stem cell-derived pancreatic progenitors choose between islet and enterochromaffin (EC)-like fates - and how we can steer that choice! A story in a few tweets…
Full paper 👉 https://t.co/auNYTcqIqG

[Paraish S. Misra, M.D. @ParaishM]

14/14 This project was a long, shared labour of love. Huge gratitude to the brilliant team who carried it forward @MCNostroLab, and to our friends in the Pavlinkova lab (@GPavlinkova), whose elegant in vivo ISL1‑CKO experiments were key to revealing the pancreatic EC story.