Persevere Therapeutics

We are a clinical-stage oncology company dedicated to advancing a novel antineoplastic therapeutic for patients with difficult-to-treat cancers.

[Persevere Therapeutics @PersevereTx]

Platinum-resistant ovarian cancer remains one of the most challenging and underserved areas in gynecologic oncology, leaving patients with limited effective options and a poor prognosis.

https://t.co/WyKnOBFC3W

#SeedFunding #OvarianCancer #PROC #WomensHealth #NeverGiveUp

[Persevere Therapeutics @PersevereTx]

Why We Exist. To making a significant improvement in clinical outcomes and the lives of cancer patients everywhere.

https://t.co/WyKnOBFC3W

#Persevere #SeedFunding #BiotechDeal #OvarianCancer #PROC #WomensHealth #NeverGiveUp

[Persevere Therapeutics @PersevereTx]

Persevere, our commitment to women living with ovarian cancer.

https://t.co/WyKnOBFC3W

#Persevere #SeedFunding #BiotechDeal #OvarianCancer #PROC #WomensHealth #NeverGiveUp

[Persevere Therapeutics @PersevereTx]

Honored to be included in Keiretsu’s 2026 Annual Life Sciences Summit in Chicago on March 12th. Looking forward to sharing and learning with other thought leaders and colleagues in the industry.

https://t.co/EUS7R4fWjb
#Persevere #SeedFunding #OvarianCancer #PROC #NeverGiveUp

[Persevere Therapeutics @PersevereTx]

Our Founder and CEO Greg Bosch, shares his mission for the company and commitment to "Never. Give. Up."

https://t.co/hycNWChoIm

#Persevere #SeedFunding #BiotechDeal #OvarianCancer #PROC #WomensHealth #NeverGiveUp

[Persevere Therapeutics @PersevereTx]

Persevere Therapeutics Launches as a Clinical-Stage Oncology Company with a Novel Phase 1b/2a Agent and Announces First Close of Seed Financing

https://t.co/hycNWChoIm
#Persevere #SeedFunding #BiotechDeal #OvarianCancer #PROC #WomensHealth #NeverGiveUp

[Persevere Therapeutics @PersevereTx]

Panavance is attending JPM Week in San Francisco from January 13–16!

Our CEO, Greg Bosch, invites investors to discover how Panavance is poised to transform the treatment landscape in oncology with its drug candidate, misetionamide (GP-2250). Meet with Greg to explore investment opportunities in advancing breakthrough therapies for unmet medical needs.

Let’s schedule a meeting!

✅ Connect with Greg via BIO @JPM Partnering

📩 Or reach out directly to Carol Gorman at [email protected]

Visit our website to learn more: https://t.co/XQ5dnUdMkS

#JPM2025 #JPM25 #BioWeekSF #Biotech #InvestorMeetings

[Persevere Therapeutics @PersevereTx]

Panavance presented #newresearch highlighting the unique mechanism of action of misetionamide and its ability to directly inhibit oncogenic transcription factor, c-MYC building upon previous confirmation of misetionamide’s direct inhibition of NFkB and supporting its potential in the fight against various #cancers.

Learn more about how misetionamide could transform treatment options for #cancerpatients in our latest press release: https://t.co/JrH5PmrB8H

#cancerresearch #preclinicaldata

[Persevere Therapeutics @PersevereTx]

Dr. Anup Kasi, Associate Professor, Medical Oncology, at The University of Kansas Cancer Center, presented an interim update on the on-going Phase 1 clinical trial of misetionamide (GP-2250) combined with gemcitabine in the challenging treatment of pancreatic adenocarcinoma at the 2024 Visceral Medicine Congress in Germany last week. Key highlights include:

• Combination of misetionamide and gemcitabine demonstrating a very good safety and tolerability profile.
• Interim results show ~40% of patients achieved either a partial response or stable disease.

The Phase 1 dose-selection study remains ongoing with final results expected in 2025. For more information, check out today’s press release here:
https://t.co/jFCKGplAHq

#visceralmedicineconference #pancreaticcancer #pancreaticadenocarcinoma #clinicaltrialresults

[Persevere Therapeutics @PersevereTx]

Dr. Anup Kasi will be presenting an interim update of the on-going clinical trial results of misetionamide (GP-2250) at the Visceral Medicine Conference in Leipzig, Germany on October 4th at 1:45 p.m. CEST.

This presentation will provide an update on Panavance’s Phase 1 trial exploring the safety, tolerability and early potential of misetionamide (GP-2250) in advanced pancreatic adenocarcinoma.

For more details: https://t.co/ZaVpfAGINs

#visceralmedicineconference #pancreaticcancer #pancreaticadenocarcinoma #clinicaltrialresults

[Persevere Therapeutics @PersevereTx]

Dr. Anup Kasi will be presenting at the Visceral Medicine Conference in Leipzig, Germany on Oct. 4. This will be the first presentation of misetionamide (GP-2250) clinical results diving deeper into its Phase 1 trial to evaluate the safety, tolerability, and preliminary efficacy of misetionamide in advanced pancreatic adenocarcinoma.

Learn more here: https://t.co/ZaVpfAGaXU

#visceralmedicineconference #pancreaticcancer #pancreaticadenocarcinoma

[Persevere Therapeutics @PersevereTx]

September is Ovarian Cancer Awareness Month, a time to educate and heighten awareness about #ovariancancer.

Ovarian cancer is the 8th most common cancer and the 5th leading cause of cancer death in women.

Panavance is developing misetionamide (GP-2250) for ovarian cancer.

We recently announced foundational preclinical results of misetionamide in ovarian cancer which demonstrated profound effects on tumor metabolism, anti-angiogenic activity, protein synthesis, and DNA transcription.

Learn more about our work here:
https://t.co/vGlK4Qgpof

#ovariancancerawarenessmonth #oncology

[Persevere Therapeutics @PersevereTx]

At Panavance, we focus on what matters most—improving therapeutic outcomes for cancer patients.

Misetionamide (GP-2250), a tumor-cell selective agent, is bringing new hope to the fight against #cancer through novel science. Misetionamide exhibits powerful synergistic activity with existing #oncologytherapies in preclinical studies and demonstrates remarkable safety and tolerability in the ongoing clinical trial.

Like the mechanism of misetionamide, our mission is to disrupt cancer’s energy. Learn more about our clinical-stage drug here. https://t.co/vbvAdI3mYP

#clinicaltrial #oncology #pancsm

[Persevere Therapeutics @PersevereTx]

Misetionamide (GP-2250) has shown broad utility in various #cancer indications through preclinical studies.

Panavance is focusing on the treatment of #pancreatic and #ovarian cancer, two diseases with significant unmet needs.

Take a look at our pipeline: https://t.co/A2GqagdiSc

#CancerResearch #ClinicalTrials #PancreaticCancer #GP2250

[Persevere Therapeutics @PersevereTx]

Panavance is pleased to announce the publication of preclinical data on misetionamide (GP-2250) in #ovariancancer in the journal, Cancer Medicine titled, “Mechanism and Rational Combinations with GP-2250, a Novel Oxathiazine Derivative, in Ovarian Cancer.” The publication by Kim, et al. (2024) at MD Anderson Cancer Center reports the research on misetionamide which demonstrates significant single agent activity and synergy with either PARP inhibitors or bevacizumab and profound effects on tumor metabolism, anti-angiogenic activity, protein synthesis, and DNA transcription.

Read the press release here: https://t.co/vGlK4Qgpof and check out the scientific paper here: https://t.co/WDrfft7ViR.

#oncology #cancerresearch

[Persevere Therapeutics @PersevereTx]

Panavance is deeply rooted in science which has led the development of our clinical program for #pancreaticcancer.

With over 15 publications in the world’s peer-reviewed cancer journals, Panavance continues to pioneer groundbreaking research in #oncology including #ovariancancer and #pancreaticcancer.

Check out the publications here: https://t.co/HSb6SQwLns

#cancerresearch #clinicaltrials #oncology #breakthroughscience

[Persevere Therapeutics @PersevereTx]

Our on-going Phase 1 #clinicaltrial of misetionamide (GP-2250) in #pancreaticcancer has shown encouraging data and continues to demonstrate a very good tolerability profile.

For more information on our clinical trials, visit: https://t.co/6U0frHVVcp

#oncology #cancerresearch #pancsm

[Persevere Therapeutics @PersevereTx]

Take a look into the novel science that powers misetionamide’s (GP-2250) mechanism of action in our brochure here: https://t.co/4P4bONUaw7

#disruptingcancersenergy #pancreaticcancer #ovariancancer