Phyllis Sin

#WIC | General Cardiologist | @MBACSNetwork | @umanitoba Cardiology 2022 | @usask Internal Medicine 2019 | @UL BMBS 2016 | @WesternU BMSc HSp Physiology 2012 |

[CJC Journals @CJCJournals]

National survey of #Canadian #Cardiac Centres and physician self-reported practices and experiences with their respective centre’s #Indigenous patient support services in #CJC @shuangboliu @umanitoba @MBACSNetwork 👉 https://t.co/8dyYltPhtm

[NEJM @NEJM]

Presented at #ESCCongress:

In patients with ST-segment elevation myocardial infarction, immediate multivessel PCI was noninferior to staged multivessel PCI with respect to the risk of death and adverse cardiovascular events at 1 year.

Full results of the MULTISTARS AMI trial:

[NEJM @NEJM]

Late breaking at #ESCCongress:

In a randomized trial involving patients with advanced heart failure and atrial fibrillation, catheter ablation decreased the risk of cardiovascular events at a median of 18 months.

Read the full CASTLE HTx trial results: https://t.co/g0Hjnqoypi

[Dr. Martha Gulati ♥️🫀❤️‍🩹🇨🇦 @DrMarthaGulati]

#ESCCongress #hotline
ATTRibute Trial: acoramidis in TRC
♥️RCT ATTR-CM+ class I-III, mostly male
♥️⤵️ all cause ☠️ , HF 🏥with acoramidis tx
♥️results consistent across subgroups
♥️better QOL with tx, TTR stable, ⤴️6MWD
♥️ safe well tolerated

[Phyllis Sin @PhyllisSin]

Driving home #HFpEF 🫀obesity phenotype:
1️⃣⬆️comobidities = ⬆️inflammation
2️⃣⬆️☠️morbidity and 💨symptoms
3️⃣📋@escardio guidelines recommend SGLT2i (class1a)
4️⃣💪🏼evidence for GLP1RA to improve KCCQ, 6MWT, & ⬇️NT pro BNP
@CanHFSociety #ESC2023

[Phyllis Sin @PhyllisSin]

Excellent summary of established & upcoming trials re: timing of #AS intervention. Awaiting results for what to do with:
1️⃣Severe AS w/o guideline criteria (Early TAVR, EXPAND TAVR II)
2️⃣Moderate AS w/ #HF (TAVR Unload, PROGRESS)
@escardio #ESC2023

[Phyllis Sin @PhyllisSin]

@SiemensHealth showing #AI 🤖 assistance in #echo for efficient and consistent LV & RV #strain analysis as well as volumetric calculations helpful for serial studies in cardio-onc @CSEchoCa @escardio #ESC2023

[Phyllis Sin @PhyllisSin]

Great #ESC2023 summary 📋 #AI #machinelearning for #HF:
1️⃣Screening/diagnosis 🔍
2️⃣ID phenotypes & #LVEF 🫀
3️⃣Predict clinical events☠️
4️⃣CRT/ICD responders📈
5️⃣GDMT optimization 💊
6️⃣RCT design 📚
@hvanspall @CanHFSociety @escardio @SCC_CCS

[Dr. Martha Gulati ♥️🫀❤️‍🩹🇨🇦 @DrMarthaGulati]

STEP HFpEF #hotline #ESCCongress
#HFpEF #semaglutide RCT
♥️EF 57%, >50% 💃🏻
♥️few on SGLT2i
♥️improved QOL + body weight
♥️⬆️ 6 min walk ⬇️ CRP ⬇️ BNP ⬇️ HF
🎯 Semaglutide as a tx for HFpEF💥

[Phyllis Sin @PhyllisSin]

🤩👀 #HEARTROID sim for #CAD #TAVI #MV #ASD #PFO #LAA #EPS 🇯🇵@osaka_univ_e #JMC @escardio #ESC2023 @SCAI @SCC_CCS_Trainee @SCC_CCS #MedEd @ajlavoie4hearts @BElbarouni @AHRavandi @AshishHShah3 @shuangboliu @dehghani_payam @Cardio_Girl @ChangeAtHeart @RobinACHD @ShelleyZieroth

[Phyllis Sin @PhyllisSin]

Successful #escaperoom ambulance 🚑for #TTR Amyloidosis with colleagues from Argentina 🇦🇷 @PfizerNL 🇳🇱 @escardio #ESCCongress #ESC2023

[Phyllis Sin @PhyllisSin]

@ivanaisgum dropping #AI 🤖based multimodality imaging power 💪🏼in predicting challenges like #CRT response using #echo 🔉and #cmri 🧲before device implant🔪 @escardio @CanHFSociety #ESCCongress ❤️

[Phyllis Sin @PhyllisSin]

Kicking off #ESCCongress ❤️with #AI #ECG 🤖accurately identifying age, ethnicity as well as diagnosing and predicting #HFrEF & #HFpEF. #AI #ECG is as good as #echo for #diastology in a fraction of the time @MayoClinic @escardio

[Phyllis Sin @PhyllisSin]

My heart is full after connecting with some of my amazingly supportive mentors and colleagues #CCC2022 @SCC_CCS @SCC_CCS_Trainee @shuangboliu @ajlavoie4hearts @MBACSNetwork #CardioTwitter

[Phyllis Sin @PhyllisSin]

#cardiorenal #HF ❤️ #CKD 🥃#DM 🍬guidelines 1️⃣drop in egfr w/in 30% ok after #SGLT2i 2️⃣refer pts with KFRE 5yr risk> 5% to nephro 3️⃣ #GLP1RA to ⬇️stroke risk in pts with DM&ASCVD 4️⃣ SGLT2i & GLP1RA don’t cause hypoglyc on their own @CanHFSociety @SCC_CCS @ShelleyZieroth

[Phyllis Sin @PhyllisSin]

#heartteamapproach for complex #IHD & #VHD: #TAVI is 🔝for all #AVR & ✅for all STS risk levels but need 🕵🏻focused approach especially for young patients as LT data only known for ~8yrs out @Cardio_Girl @OuzounianMD @Jse2230 @BaineyKevin @SCC_CCS #CCC2022 #heartteam ❤️

[Phyllis Sin @PhyllisSin]

@thaiscoutinhoCV @paquin_amelie #danielesau @stelladaska & #bethabramson 1️⃣lowest estrogen MHT for #menopause but not 1’/2’ prev of CVD 2️⃣higher ❤️FRS in premature menopause 3️⃣take a menstrual/obs hx #herheartmatters #Women #CCC2022 #womenshearthealth @cwhhs @SOGCorg @SCC_CCS

[Phyllis Sin @PhyllisSin]

@ajlavoie4hearts @SCC_CCS @lizswiggum @JessicaLuc1 @ShelleyZieroth these are definitely in oprah's sitting shoes category!! 😂gorgeous!!

[Phyllis Sin @PhyllisSin]

6/Overview of #CCCongress @CanHFSociety SPOTLIGHT: HF PHENOTYPES & PERSONALIZING HF CARE ❤️🖤Use this summary to guide HFrEF management w/in provincial funding restrictions ofc🇨🇦 @ShelleyZieroth @AniqueDucharme @JustinEzekowitz @DktrV+ more! @SCC_CCS @SCC_CCS_Trainee

[Phyllis Sin @PhyllisSin]

5/ Overview of #CCCongress @CanHFSociety SPOTLIGHT: HF PHENOTYPES & PERSONALIZING HF CARE😫➡️😁 ARNI💊start low & go slow📈well before discharge 🏥➡️🏠& don't sweat😅in robust ambulatory HF @ShelleyZieroth @AniqueDucharme @JustinEzekowitz @DktrV+ more! @SCC_CCS @SCC_CCS_Trainee