Jan Leipert

PhD student @kieluni, MS-based proteomics and microfluidics for sample preparation

[Pastel BioScience @PastelBio]

Acetic acid is a superior ion pairing modifier for sub-nanogram and single cell proteomics https://t.co/jOKfaIqQCB

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#proteomics #prot-preprint

[Jan Leipert @PingvinEl]

@JefimVogel @jasonhickel Congrats! 👏

[Jan Leipert @PingvinEl]

Thanks to #projectDEAL, our new top-down nanoproteomics paper published in @angew_chem will remain Open Access :-)

[Angewandte Chemie @angew_chem]

Digital Microfluidics and Magnetic Bead-Based Intact Proteoform Elution for Quantitative Top-down Nanoproteomics of Single C. elegans Nematodes (Andreas Tholey and co-workers) @PingvinEl #openaccess thanks to #projektDEAL https://t.co/1tg7VGc3wz

[Jan Leipert @PingvinEl]

@ucdmrt and FAIMS!

[Jan Leipert @PingvinEl]

Very happy to share our new paper published in @angew_chem, where we investigated single C. elegans nematodes by top-down proteomics! #nanoproteomics #microfluidics
https://t.co/TQFp1xrbEt

[Journal of Proteome Research @JProteomeRes]

Searching for a universal, bottom-up proteomics method? @MaxPerutzLabs performed a comparative survey of the 16 most common methods to provide a basis for selection preparation strategies in MS proteomics. https://t.co/TsSDpX7Pnu

[Jan Leipert @PingvinEl]

@ProteomicsNews Was this with the TimsTOF-SCP and evosep whisper LC?

[Nobu Takemori @nobu_takemori]

We have an outstanding lineup of speakers for the JPrOS Webinar "Top-Down Proteomics", gathering online from 🇯🇵, 🇩🇪, 🇫🇷 @dtabb73, and 🇺🇸 @MoweiZ, @JoeLoo85614818! Starts at 14:30 in continental Europe and bright and early at 5:30 on the West Coast!　https://t.co/R1v8ZGCdk4

[Vadim Demichev @DemichevLab]

Our FragPipe + DIA-NN 1.8.1 paper, making dia-PASEF truly sensitive, is finally out! 5.3k proteins @ 200 samples/day, 7.4k proteins lib-free from 10ng, 9k proteins - from 200ng. https://t.co/3Cb8vDdE5n

[YingZhu @NanoPOTS_SCP]

As single cell proteomics person, we always try to compare protein measurements to transcript, what if we can do both on the same cells? Great job by @cajun_science and collaboration between @EMSLscience and @Cellenion https://t.co/ewYEQUVhV0

[Angewandte Chemie @angew_chem]

Cold Denaturation of Proteins in the Absence of Solvent: Implications for Protein Storage (Barran) @PerditaB @EmmaNorgate #openaccess https://t.co/Z59fq4rg1l

[Oded Rechavi @OdedRechavi]

Shotgun sequencing

[Vadim Demichev @DemichevLab]

What if the mass spec detector suddenly became 10x more sensitive? Proteomics of sub-microgram sample amounts now possible even on a high-flow LC @ 800 μl / min. Speed & sensitivity are now combined: Zeno SWATH @SCIEXnews, DIA-NN. https://t.co/FUb139cinF.

[Oded Rechavi @OdedRechavi]

Giving a lab meeting when you don't have any data
https://t.co/Q1FwZLnHDW

[Journal of Proteome Research @JProteomeRes]

The @MacCossLab collaborated with @Smith_Chem_Wisc & others to reevaluate the current method of protein quantification in bottom-up proteomics. https://t.co/JeOQVYF5BN

[Jan Leipert @PingvinEl]

Free, virtual top down proteomics meeting, with very interesting talks!

[Journal of Proteome Research @JProteomeRes]

Researchers characterize the differences between single-cell spectra and bulk spectra by examining fundamental spectral features that are likely to affect peptide identification performance at low levels of input sample material. https://t.co/8jSnyb6E2A

[Sandra Ciesek @CiesekSandra]

unsere ersten Daten zur
Neutralisation von Omicron versus Delta sind fertig: 2x Biontech, 2x Moderna, 1xAZ/1x Biontech nach 6 Monaten 0% Neutralisation bei Omicron, auch 3x Biontech 3 Monate nach Booster nur 25% NT versus 95% bei Delta. Bis zu 37fache Reduktion Delta vs. Omicron

[Joel Steele 🧪💉⚡💥📹 @JoelisSteele]

We are looking for another member to join our proteomics team!

We are doing single cell and you can get your hands on all of the different techniques with all of the coolest toys !
#proteomics #postdocjobs #postdocs #academia #MassSpec
https://t.co/OnHS3X2XbL

[Pastel BioScience @PastelBio]

Use of Linear Ion Traps in Data-Independent Acquisition Methods Benefits Low-Input Proteomics | https://t.co/gngmfx9PL1 #proteomics