Former PhD student @Basler_Lab working on intracellular pathogens - I like tea.
Now PostDoc @EPFL in the Persat lab working with cool bacs- I still like tea.
The lab's latest NINJ1 story is out on @biorxivpreprint 🥳 Ninjurin-1 mediated plasma membrane rupture is a two-step process requiring cell swelling https://t.co/4ILGEpjAVi
(1/6) Really jazzed to have this out - my first @wellcometrust fellowship paper! https://t.co/uhA1c5Qv0M
Can bacteria evolve resistance to competitors' T6SS weaponry? We find that the answer depends on **how many toxins** competitors are using. A thread:
🚨🔬Excited to share our new paper now out in @NatureMicrobiol!
Using Tn-seq + live imaging in engineered airway organoids, we explored the fitness tradeoffs P. aeruginosa faces while growing and surviving antibiotic treatment on the mucosal surface.
🔗 https://t.co/DCPVogORDv
Researchers @Biozentrum@UniBasel_en have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. The bacteria use a kind of nano-sized harpoon. @Basler_Lab
https://t.co/wV2Vvl51rw
If anyone wants to chat about it feel free to shoot me a message. I am always happy to talk about science.
Big thanks to @Basler_Lab@yunnhwen@christy_chc non-twitter Patricia, our reviewers and editor.
🔬 Our paper is live! 🎉Dive into the wild world of Burkholderia's secret tactics – plenty of #T6SS assemblies, actin acrobatics, and some galectin/dynamin inside host cells. We got plenty of images and some cool movies! https://t.co/DRDRUNv7LK
Snapshot of infection of host cells by Burkholderia thailandensis (white). The pathogen polymerizes actin (green) to move from one host cell to another and breaks the membranes (magenta) by its Type VI Secretion System #T6SS.
https://t.co/zpqk4ZOWVk
Congratulations to Miro (@PlumifyM), Christy (@christy_chc), Patricia and others on a beautiful paper showing #T6SS role in spreading of Burkholderia thailandensis between infected cells:
https://t.co/V8WbSv8W5B