Precigenetics

autonomous biology is here.

[Precigenetics @Precigenetics]

Happy GPT 5.6 day! We dream of fighting disease with this kind of intelligence. In that spirit, here is a first preview of Cell Cinema, the future cell token for AI models.

And a first for humanity: we recorded ferroptosis label-free, in real-time.

A huge feat for biosciences.

[Precigenetics @Precigenetics]

@ItsElanaGold Precigenetics

[Precigenetics @Precigenetics]

We have decided to test our technology on a rare sample known as Jeremy stamper.

[Precigenetics @Precigenetics]

@romyroyz First in humanity.

[Precigenetics @Precigenetics]

At Precigenetics we take our scientific claims very seriously.

While label-free morphology linked to cell death have existed, achieving native chemistry - spatially resolved actual biochemical process in live cells without labels - is a hard technical challenge.

Receipts 🧵

[ROMY ROY @romyroyz]

@Precigenetics Label free real-time imaging /tracking of ferroptosis existed for years, so it's not first for humanity ,is it the spectral mapping that is proprietary?

[Precigenetics @Precigenetics]

I don’t know. Ours seems to be doing fine.

[Tanning Salon Don @TheSalonDon]

Female founders don’t even know they are scamming

They see no difference between making up projections and making up actuals

They believe the business is
- Wearing suits
- Holding meetings
- Glass offices
- Speaking at conferences

Basically what an 8 year old thinks a CEO does

Not
- Hitting your numbers
- Solving hard problems
- Honoring your commitments
- Creating value for customers

[Precigenetics @Precigenetics]

Not this one.

[Tanishq, Ph.D. at ICML @iScienceLuvr]

AI startups are actually wrappers to turn funding into lit socials/parties

[Precigenetics @Precigenetics]

@DVirilis Yes! Totally possible. Considering this.
@SasaanAShowghi

[Precigenetics @Precigenetics]

Happy GPT 5.6 day! We dream of fighting disease with this kind of intelligence. In that spirit, here is a first preview of Cell Cinema, the future cell token for AI models.

And a first for humanity: we recorded ferroptosis label-free, in real-time.

A huge feat for biosciences.

[Lysander Boomer @LysanderBoomer]

What you are seeing here is incredible. They've built a mechanism that allows them to observe cells reacting to drugs without disturbing the cells. This can unlock discoveries like understanding exactly how cancer cells become treatment resistant allowing better targeting.

[Precigenetics @Precigenetics]

We have a high density of talented people.

Thanks to those who voted for us. We are cross disciplinary.

We will keep growing and this year we will exceed expectations.

[Chris Barber (in SF) @chrisbarber]

I asked people which companies have the highest density of talented people they know:

1st. Cognition - 9 votes
Equal 1st. Anthropic - 9 votes
2nd. Modal - 5 votes
3rd. OpenAI - 4 votes
4th. Standard Intelligence - 3 votes
4th. Cursor - 3 votes

Two votes each:
- Ramp
- Flapping Airplanes
- DeepMind
- Long Lake
- Applied Compute

One vote each:
- SpaceXAI
- SpaceX (treated separately, one vote was for the AI lab subsidiary and one was for the rocket team)
- American Terawatt
- Mechanize
- Olix
- Fluidstack
- Chai Discovery
- Sail Research
- Etched
- Core Automation
- Specter
- Clay
- Applied Intuition
- Sierra
- Hivemind
- Bitrig
- Retro
- Thinking Machines
- Decagon
- Precigenetics
- Pangram
- Reflect
- Thrive Holdings
- Adaption

[Tom Wilson @monistowl]

I continue to be impressed by actually-existing bio/acc

[Parmita Mishra @parmita]

first time in history ANYONE recorded this label-free, alive, real time. this is HUGE and no one is talking about it.

Ferroptosis = cancer kill itself.

The final boss of “AI drugs” are the cells that fight them.

We just FILMED the FIGHT. here’s why it matters.

🧵

[Precigenetics @Precigenetics]

Deeptosis
Wang et al. (2026)

Uses brightfield + DL for label-free cell death classifier.

Notes difficulties in direct application to new conditions and need for standardized workflows. morphological features alone lack specificity.

[Precigenetics @Precigenetics]

https://t.co/CHPXx6J02p 2024 highlighted the problems with fixative solution selection as well as the following

[Precigenetics @Precigenetics]

In CellDeathPred from 2023, they highlight that previous staining methods were selective/specific to one death modality (e.g., TfR1 for ferroptosis), and their approach tries to move beyond that by using general cellular content profiling.

[Precigenetics @Precigenetics]

@vizience @geladaris_georg @parmita Hope you’re happy with your choices

[Precigenetics @Precigenetics]

We care.

[pratisabrat @functionofpoem]

@kmr_dilip I’ve hopes with whatever @parmita is doing w @Precigenetics, I hope people are saved from this form of suffering.