#OnThisDay 1978: Tomorrow's World gave audiences a true world first as Dr Peter Mansfield of the University of Nottingham demonstrated the first full body prototype device for Magnetic Resonance Imaging (MRI), allowing us to see inside the human body without the use of X-rays.
The Davy Medal 2023 is awarded to Professor Dame Margaret Brimble FRS for outstanding contributions to organic chemistry with wide-ranging applications across the life sciences. #RSMedals https://t.co/sMJcDsnu19
📈 Read one of the most read open access articles published in July, "Silver(I)-Catalyzed Synthesis of Cuneanes from Cubanes and their Investigation as Isosteres". @DrGrahamNewton @ChemistryUoN@SpiroChemAG
🔗 https://t.co/5sZqouF0QL
📈 Check out one of the most read open access articles in July: "Oxetane Synthesis via Alcohol C–H Functionalization" @SilviResearch@AstraZeneca
Read it in full here ➡️ https://t.co/mZsXUyd3Mx
Happy to share our latest work in collaboration with @AstraZeneca online @J_A_C_S. Forging oxetanes from sp3 alcohols. https://t.co/afT8nHeTsn @ChemistryUoN
The University of Nottingham has a major initiative in Physical Chemistry, recruiting two positions at assistant/associate professor and one at chair level:
https://t.co/zo9jpqd0dE https://t.co/G6WjIMUZfw
Liam Ball and his team at the @UniofNottingham used a regiodiversion of electrophilic #aromatic substitution for the C–H arylation of phenols.
More about their research in this article 👉 https://t.co/xUxlIXXH6j
14 simplified natural product syntheses reported today in @ChemRxiv : https://t.co/fsK5Zx794f. These syntheses are enabled by a next generation doubly decarboxylative cross coupling (dDCC) that tolerates alpha-heteroatom substituents. In addition to the critical Ag-additive that turns on reactivity, the ligands play a key role in stereo controlled couplings.
Imagine a world where natural products like polypropionates can be made without recourse to aldol or epoxide chemistry but instead by just putting ubiquitous acid building blocks together like LEGOs.
Retrosynthetic analysis is often taught using the concept of "polar bond analysis" which has inadvertently led to an over-reliance on protecting groups, functional group manipulations, and redox-fluctuations. The advantages of radical retrosynthesis (https://t.co/fTSPpwrEJV), which is polarity agnostic, is on vivid display in this disclosure.
Thanks to our amazing collaborators at BMS (medchem and process), Pfizer, Biogen, and LEO Pharma.
We also still have studentships available via our @CDTSusChem @ChemistryUoN on the development of new biocatalysts to functionalise peptides and proteins!
https://t.co/WbKSZnI36s
We have a PhD studentship available @ChemistryUoN funded by @LeverhulmeTrust to develop the visible-light-mediated functionalisation of amino acids, peptides, and proteins! If you have an interest in synthetic chemistry/chemical biology, come work with us!
https://t.co/0Q3uQI26Bs
Huge congrats to Distinguished Professor Dame Margaret Brimble @BrimbleM who received the news she's been waiting for, with the FDA approving her drug Trofinetide today. She identified it in a lab @ScienceUoA. Remarkable. https://t.co/18pCpcuEzb #womeninscience#rettsyndrome
Congratulations to Professor Sir David MacMillan @dmac68, formally invested Knight Bachelor of the British Empire by King Charles III this morning #BuckinghamPalace (pictured here with family members)!