Protocol Labs

We are an innovation network of 700+ teams and projects, driving breakthroughs in computing to push humanity forward.

[Protocol Labs @protocollabs]

Sonalis, one of the teams funded by @ARIA_research, is working toward read/write of electrical signals anywhere in the brain without opening the skull.

@JacquesCarolan, founding Program Director at @ARIA_research, on the @JuanBenet Podcast >>> https://t.co/WsRPe6zQyA

[Protocol Labs @protocollabs]

What does good operational security look like for web3 teams?

Join @audit_wizard CEO Joe Van Loon, former Security Engineer at Apple and Amazon, for a practical OpSec workshop.

📅 June 9
📍Oasis by Workville, NYC
https://t.co/NtlXPpowtz

[Protocol Labs @protocollabs]

Most neurotech approaches require opening the skull. @ARIA_research's £50m Massively Scalable Neurotechnologies program is asking the field whether high-performance neurotechnology can be delivered to the brain in a 30-minute outpatient procedure without transcranial surgery.

Full conversation with @JacquesCarolan on the @JuanBenet Podcast >>> https://t.co/v18BHbBqA6

[Protocol Labs @protocollabs]

The best model for the human brain is the human brain. Jacques Carolan argues that collecting large-scale human neural datasets (safely and at scale) is necessary for finding new therapeutic targets.

Full conversation with @JacquesCarolan on the @JuanBenet Podcast >>> https://t.co/v18BHbBqA6

[Protocol Labs @protocollabs]

Dubai built a new jurisdiction. Estonia digitized government services.

Can Argentina do both?

Join founders, investors, and policymakers on June 5 to discuss whether Mendoza's first Digital Zone can compete for global capital.

#NYTechWeek
https://t.co/PEEhxmqbZ1

[Jacques Carolan @JacquesCarolan]

super exciting work developing closed-loop gene therapies — led by @gabrilignani and his exceptional team Richard Rosch @JerzySzablowski @mikhailshapiro

[Protocol Labs @protocollabs]

Surges of neural activity can overwhelm the brain's inhibitory mechanisms, triggering a seizure. @ARIA_research is funding a team at UCL to develop a gene therapy that allows neurons to sense rising excitation as a seizure begins and strengthens their own potassium channels to quiet things back down.

Full conversation with @JacquesCarolan on the @JuanBenet Podcast >>> https://t.co/v18BHbBqA6

[Protocol Labs @protocollabs]

DBS has been FDA-approved for 25 years and is covered by most insurance. But only ~ 0.1% of Parkinson's patients receive it. Jacques Carolan at @ARIA_research is working to close that gap.

Full conversation with @JacquesCarolan on the @JuanBenet Podcast >>> https://t.co/v18BHbBYpE

[Arkhai @arkhai_io]

Today we're launching Simple Compute Market (SCM).

The market is simple: agents find compute, negotiate, settle, and get access without a human driving every step.

Open-source. Agent-driven. Public good. No token. No fees.

[Protocol Labs @protocollabs]

Join @protocollabs, @Techweek_, and @ethereumconf for a week of collaboration and networking.

📅 June 7–11
📍 Oasis by Workville, NYC

Register: https://t.co/X8BYTIgsb9
Updates: https://t.co/pxNvNkp1un

#NYTechWeek

[Protocol Labs @protocollabs]

2/ @PrecisionNeuro_ has partnered with UChicago Medicine's Sensorimotor Bionics Group to advance AI-driven neural cursor control and neuroprosthetics.

🔗 https://t.co/D8ujIPvWPC

[Protocol Labs @protocollabs]

What's on our Neurotech Network Radar?📡

See below. ⬇️

🧵

[Protocol Labs @protocollabs]

1/ The FDA has approved @motifneuro RESONATE study, evaluating the DOT, a blueberry-sized implant that stimulates depression-linked brain circuits without ever contacting the brain.

🔗 https://t.co/tRqTHiFBj2

[Web3Privacy Now @web3privacy]

We have a dream that multidisciplinary people from different fields will come together via the Neo-Cypherpunk Summit in Berlin 🇩🇪

1 day of incredible 70 thinkers from @torproject to @ethereumfndn 📢

1000 individuals curious about anti-Big Tech, democracy, open-source software, privacy, and freedom ✊

Diverse subjects from encrypted messengers to politics of Gen AI, across solidarity movements & decentralised socials.

We have a dream, and we are making it real: https://t.co/8BeXwwEctF

[bidhan ✈️ CVPR @bidhan]

We're releasing Paris 2.0, which, to our knowledge, is the world's first decentralized trained video generation model.

We benchmarked it against a monolithic model trained on the same data and compute budget, and Paris 2.0 outperformed the monolithic by ~2x on FVD benchmark.

[Protocol Labs @protocollabs]

Build. Ship. Compete. #NYTechWeek

Join the @spacetime_db Launchpad Hackathon to build and launch a multiplayer or collaborative app in one weekend.

June 5th 8:00 PM – June 7th 2:00 PM | The Yard: Herald Square
https://t.co/gdCax7H4fv

[Jacques Carolan @JacquesCarolan]

I had an absolute blast chatting with @juanbenet about the future of neurotech.

For neurotech to reach everyone who needs it, we need treatments that are both more effective and dramatically easier to deliver. That’s the ambition behind the programmes I’m leading at @ARIA_research.

Juan is a super thoughtful host, and this is the deepest conversation I've had about my journey, what it means to lead ambitious R&D, and the future we could unlock if next-generation brain therapies can genuinely scale.

[Juan Benet @juanbenet]

Episode 3 of my new podcast features Dr. Jacques Carolan (@JacquesCarolan), a founding Program Director at ARIA (@ARIA_research), the UK’s Advanced Research and Invention Agency. He directs two neurotech programs aimed at one of the most important opportunity spaces: developing tools and systems to interface, at scale, with the human brain.

One program is built on the idea that brain disorders are circuit problems, and funds tools to target those circuits with molecular precision across the whole brain. The other aims to deliver high-performance neurotech to the brain non-invasively or at most in a 30-minute outpatient procedure.

We dig into the engineering and biology behind both programs, potential scaling unlocks for the field, how ARIA programs drive breakthroughs, Jacques background, the role of media in shaping the future, and much more. I hope you enjoy the conversation!

Other links to this episode and references below.

Chapters
00:00:00 Introduction
00:01:22 Why 20 years of neurotech breakthroughs haven't reached patients
00:04:08 The two variables that determine whether any medical technology gets adopted
00:09:17 Brain disorders cost the UK £100B/year and we're barely treating them
00:16:15 Using stem cells and gene therapy to build better brain interfaces
00:21:40 Self-regulating gene therapy that helps the brain quiet its own seizures
00:24:03 The non-technical reasons transformative neurotech fail to reach patients
00:31:34 Watching a 30-second brain ablation stop severe tremors
00:38:11 The case for delivering brain implants and therapies without opening the skull
00:50:56 Why high technical uncertainty makes distributed teams better than vertical integration
01:02:55 Why the UK keeps producing world-class neuroscience but not world-class neurotech companies
01:11:04 What AI-driven hypothesis generation means for breakthroughs per pound
01:20:40 From quantum computing to improv comedy to running £119M government brain programs

[Science Corporation @ScienceCorp_]

Our team working on the next-generation PRIMA Glasses is focused on creating the best patient experience. How? By leveraging the “smartphone dividend.” Watch.

[Protocol Labs @protocollabs]

The next technological race may not be in space — it may be robotic, according to @lacey_wisdom and @Bholden of @PLCapital.
https://t.co/DWJcHoqpaF