Pyr Brain Game

Pyr into the brain. A game by the creators of @eye_wire.

[Eyewire @eye_wire]

We are delighted to announce that thanks to generous support from Research to Prevent Blindness @RPB_org, Eyewire II is now officially underway!

[Sebastian Seung @SebastianSeung]

The Institute for Advanced Study (@the_IAS), the fabled home of Einstein and Gödel, announces a 2026-27 program on Modeling Fly Vision, intended to refound theor/comp neuro on the bedrock of 21st century brain maps. Apply for membership! https://t.co/v4ZHjbcbUZ

[Pyr Brain Game @PyrGame]

New preprint alert: hippocampus CA3!

∼1×1×0.1mm3 volume with 1,815 pyramidal neurons, 229 inhibitory cells, and 55,000 mossy fibers (like the ones shown below). Access the data at https://t.co/AQ8hSJvgjb and explore the preprint below

[Zhihao Zheng @zhihaozheng]

Excited to share a connectomics dataset of hippocampus CA3.
Explore the dataset: https://t.co/FpgI5YyUzG
Paper introducing the dataset and some of our discoveries: https://t.co/ORqWNuc2d3

[Pyr Brain Game @PyrGame]

A quick guide to 3D neuron navigation in neuroglancer: https://t.co/bx3C8qIYdI (try saying that 3 times fast)

Explore interactive neurons from the microns dataset: https://t.co/QXzxf3axgx

[Pyr Brain Game @PyrGame]

Venture into the hippocampus: https://t.co/C8JTizl33G

[Pyr Brain Game @PyrGame]

a little Picasso hidden in the dataset
#em found by citizen scientist Krzysztof Kruk https://t.co/AQ8hSJuItD

[Pyr Brain Game @PyrGame]

mossy fiber with several long filopodia

request early access to Pyr CA3 dataset to unlock interactive 3D: https://t.co/A6h4ESW2nE

https://t.co/yXf6rrmRZf

[Pyr Brain Game @PyrGame]

A spiraling dance of neural threads,
twisting, branching, in the head.
A tangle born of thought and time,
synapses spark and neurons climb.
In crimson rivers, pathways stream,
etching maps of hidden dreams.

Image from CA3 by Nseraf

[Pyr Brain Game @PyrGame]

>1,000 axons presynaptic to CA3 spiny pyramidal neurons have been proofread by citizen scientists. https://t.co/C8JTizlATe

[Pyr Brain Game @PyrGame]

A few presynaptic axons connecting to a CA3 pyramidal neuron. Request early dataset access here: https://t.co/AQ8hSJvgjb

[Pyr Brain Game @PyrGame]

Request early access to a new Hippocampal Formation CA3 dataset -> https://t.co/AQ8hSJvgjb

[Pyr Brain Game @PyrGame]

Coming soon: Hippocampal CA3 dataset

[Pyr Brain Game @PyrGame]

inhibitory axon of the hippocampus

[Pyr Brain Game @PyrGame]

🔥⚡ Action Potential: When neurons gossip ⚡🔥
"Hey, did you hear? Na+ rushed in, K+ stormed out, and BAM 💥 signal sent!"

Sparking thoughts, moves, and feels. https://t.co/4A740H2DOT

[Pyr Brain Game @PyrGame]

Wishing you a dazzling holiday season!

Explore an interactive 3D pyramidal neuron from deep in visual cortex: https://t.co/uHcVxhfPzg @AllenInstitute @IARPAnews @PrincetonNeuro

[Pyr Brain Game @PyrGame]

Connectomics brings the brain into focus.
Explore data from IARPA microns: https://t.co/cvpnvden9R

[Pyr Brain Game @PyrGame]

Vampyramidal neurons. Happy Halloween! #neuroscience

[FlyWire @FlyWireNews]

If you are good at programming / data analysis / algorithms and like challenges read on!

FlyWire is issuing its first Data Challenge. We'll fly the winner to Princeton to give a talk about their solution🧵

[Pyr Brain Game @PyrGame]

One huge neuron! Layer 5 excitatory pyramidal

[Tyler Sloan @quorumetrix]

My latest #neuro #visualization:
An intuition pump on connectivity in the #brain
~75K #neurons in the #MICrONS mm³.
I/O segregated by layers, function is columnar; the cortical column is the unit of cortical computation.
A typical #pyramidal cell has over >10K input #synapses.