Ryan Mayers

Postdoc studying ALS in the Kiskinis lab at Northwestern University. Interested in deurodegenerative disease, organellar dynamics, stem cells

[Ryan Mayers @RPM_in_STEM]

Congratulations to Francesco and all the others who worked on this study!

[Ryan Mayers @RPM_in_STEM]

https://t.co/a8w1TZLPpr more exciting work from my colleagues in the Kiskinis lab! They show that loss of TDP-43 function reduces UPF1 activation, in turn compromising nonsense-mediated mRNA decay that would typically degrade faulty mRNA transcripts, including in ALS patients.

[Ryan Mayers @RPM_in_STEM]

Congratulations to the Kiskinis lab and their collaborators on getting this story out, and I'm super excited to be joining you all for future work!

[Ryan Mayers @RPM_in_STEM]

I joined the Kiskinis lab at Northwestern for my postdoc starting this week - right as my new colleagues put out an exciting paper! Here, they show that TDP-43 dysfunction causes mis-splicing of KCNQ2 K+ channels in several ALS models https://t.co/78tGirj0X6

[Ryan Mayers @RPM_in_STEM]

This links TDP-43 and neuronal hyperexcitability in ALS/FTD into a single, targetable pathway! Exciting stuff with amazing translational relevance from the team, including co-first author Kelly Marshall.

[Ryan Mayers @RPM_in_STEM]

Thrilled to share that my teammates Urte, @karantarina, and I won @GlobalBRev's Voices of Tomorrow bioinnovation competition this year in the Life Sciences Consulting category! I had a great team, great mentors, and got to learn a lot - many thanks to all involved.

[Ryan Mayers @RPM_in_STEM]

Excited to present at my first ever Gordon Conference on Neurobiology of Brain Disorders! If you're curious about what happens to mitochondria when you knock out a lysosomal ion channel, stop by poster #1 today, Wednesday, or Thursday to hear about my work in the @polsterlab

[Ryan Mayers @RPM_in_STEM]

@bomba_ewa @UPennPhysiology @PennMedicine Congratulations!

[Ryan Mayers @RPM_in_STEM]

Well-deserved congratulations to lead authors Jacob Mann and Elizabeth McKenna and senior author Evangelos Kiskinis on leading this story to completion!

[Ryan Mayers @RPM_in_STEM]

Excited to see the work I did during my master's finally made it into a publication in Science Advances!

Beth, Evangelos, and the other members of this team are outstanding mentors, and I'm so glad I got to be a part of this project.

https://t.co/oqkphYQ2zW

[Ryan Mayers @RPM_in_STEM]

Having a great time at #SfN22 so far, and excited to present tomorrow morning! Stop by poster F41 if you want to hear how I'm modeling neurodegeneration-relevant inflammation/mitochondria interactions in human microglia with @polsterlab #SfN2022

[Ryan Mayers @RPM_in_STEM]

3) Just found out today I've been appointed to the NIH-funded T32 Training Program in Integrative Membrane Biology here at UMB! Much thanks to @polsterlab and @UMMedNeuro for their mentorship as I wrote my first research proposal!

[Ryan Mayers @RPM_in_STEM]

Super excited to share 3 recent accomplishments:

[Ryan Mayers @RPM_in_STEM]

2) Was named one of @GlobalBRev's Leaders of Tomorrow in global biotechnology for the year! Had a wonderful time connecting with other LoTs and competing (as a finalist team!) at #GapSummit 2022 in the UK - highly recommend others apply next year!

[MIT Science Policy Review @SciPolRev]

#Biogen's #Alzheimers drug sparked controversy due to reliance on biomarkers instead of primary data. Future policy needs to balance the risks of biomarkers with their potential benefit to patients with neurodegenerative diseases. @RPM_in_STEM #scipol
https://t.co/u4RPweXpdV