Shawn Iganej

Radiation oncologist at Southern California Permanente group

[Shawn Iganej @RadoncMD]

Bummer! Unlike the I-SABR trial by MDACC, two phase III trials of SBRT +/- immunotherapy (Keynote 867 and SWOG/NRG 1914) closed early due to lack of benefit during interim analysis :(
https://t.co/EY2scI5iag
https://t.co/uJ5Dstcufq

[Shawn Iganej @RadoncMD]

Neo-AEGIS: CROSS vs perioperative chemo (85% MAGIC, 15% FLOT). Since MAGIC is inferior to FLOT, one might expect a FLOT-only comparison to show superiority over CROSS, the subject of the ongoing ESOPEC trial. For now, I am sending most patients for FLOT!
https://t.co/dnlo4wjrK3

[Shawn Iganej @RadoncMD]

https://t.co/4J9XzEJ1O4
In the no axillary surgery arm ~98% got RT, 81% of which was to the whole breast; 94% were ER+, 99% of whom got hormonal Rx.
13.7% SLNB+ rate, and .4% 5-y axillary recurrence in the no SLNB arm, likely go up at least a little, as patients DC hormonal RX

[Shawn Iganej @RadoncMD]

The UNFOLDER trial finally published in ..... HemaSphere???!!! Is this a positive trial for RT? HMMM I am not sure and neither seem the authors!
Radiation and Dose-densification of R-CHOP in Aggressive... : HemaSphere https://t.co/UKRk3epGZj

[Henning Willers, MD, FASTRO @HenningWillers]

It is with great sadness to let you know that Jay Loeffler, MD, former Chief of #radonc @MGHCancerCenter passed away 😢

He was a clinical innovator and leader, having pioneered the use of linacs for intracranial SRS

I am forever indebted to him for hiring me & starting up my lab, and for his unwavering support🙏🙏🙏

Image below shows what he loved the most, proudly supporting others 💪

My 💔 goes out to his wonderful wife Nancy & entire family

[Shawn Iganej @RadoncMD]

Weekly Adaptive Radiotherapy vs Standard Intensity-Modulated Radiotherapy for Head and Neck Cancer https://t.co/X5Hw0oWEBd

[NBA @NBA]

AUSTIN REAVES FROM HALFCOURT AT THE BUZZER 😱

WHAT A SHOT. LAKERS LEAD ON ESPN.

[Shawn Iganej @RadoncMD]

Congrats to our chief resident Dr. Jonathan Waxer for scoring 99 percentile in the Head and Neck part of his in-service exam for the 3rd time during his residency! I am going to take this as a validation that the grueling pimping sessions every Friday morning do pay off🙃

[NBA on ESPN @ESPNNBA]

The Lakers lock in the 7-seed after starting the season with a 2-10 record‼️

[Kaiser Radiation Oncology Residency @KaiserRadOncRes]

Apply now to do a visiting rotation with us at @KP_LAMC and meet our amazing #radonc family!!

#kaiserpermanente
#thrive
@KPResidencySCal
@RadoncRes
@ARRO_org

[Onita Bhattasali @bhattasaliMD]

Long-term efficacy outcomes following SRS/FSRS/FSRT for intracranial meningioma presented at #ACRO2023
Nice work, Adam! 🤓

[Shawn Iganej @RadoncMD]

Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis https://t.co/o6XJrZU0go Another possible explanation for why HN005 failed to show non-inferiority for the de-escalated arm.

[Shawn Iganej @RadoncMD]

Medial retropharyngeal nodal region sparing radiotherapy versus standard radiotherapy in patients with nasopharyngeal carcinoma: open label, non-inferiority, multicentre, randomised, phase 3 trial https://t.co/gbxyrZ6V7l

[Shawn Iganej @RadoncMD]

HN005 excluded low neck and matted lymphadenopathy but not RPLN or overt radiographic ENE. Our group and others have found these to be adverse risk factors for early-stage HPV-related OPSCC and cautioned against deintensification:
https://t.co/bqFef0kuBa
https://t.co/QP7REh58aP

[NRG Oncology @NRGonc]

NRG-HN005 results of scheduled interim futility analysis comparing experimental arm to control arm for randomized phase II portion of the study showed that the experimental arm didn't achieve non-inferiority threshold per statistical analysis plan. https://t.co/ngHzYQ06EI

[Jason Martinez @JasonFox29]

@TomBrady I did some translating, guys. I speak “Brady.”

[Shawn Iganej @RadoncMD]

CALGB 30610/RTOG 0538 finally published. Does anyone actually use 70 Gy in this setting today??Interestingly, the 61.2 Gy arm which is probably closest to the dose most radiation oncologist use (60 Gy) nowadays was discontinued!

[Shawn Iganej @RadoncMD]

High-Dose Once-Daily Thoracic Radiotherapy in Limited-Stage Small-Cell Lung Cancer: CALGB 30610 (Alliance)/RTOG 0538 https://t.co/dRzTYVVK7Y

[Shawn Iganej @RadoncMD]

RAISE: Adjuvant RT after resection of HCC with narrow margin (≤1 cm) https://t.co/fMhStGAWts

[Shawn Iganej @RadoncMD]

Pembrolizumab versus cetuximab, concurrent with radiotherapy in patien... https://t.co/xxrKD20qyj

[Ming Zhi @mzhiMD]

👀 What's this on ASTRO Career Center? iykyk @KP_LAMC @KaiserRadOncRes @KPSCALnews @ASTRO_org #radonc #kaiser #kaiserpermanente